Translational Medicine in CNS Drug Development

Written By George G. Nomikos
Translational Medicine in CNS Drug Development
  • Publsiher : Academic Press
  • Release : 18 June 2019
  • ISBN : 0128031646
  • Pages : 458 pages
  • Rating : /5 from reviews
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Download or read book entitled Translational Medicine in CNS Drug Development by author: George G. Nomikos which was release on 18 June 2019 and published by Academic Press with total page 458 pages . This book available in PDF, EPUB and Kindle Format. Translational Medicine in CNS Drug Development, Volume 29, is the first book of its kind to offer a comprehensive overview of the latest developments in translational medicine and biomarker techniques. With extensive coverage on all aspects of biomarkers and personalized medicine, and numerous chapters devoted to the best strategies for developing drugs that target specific disorders, this book presents an essential reference for researchers in neuroscience and pharmacology who need the most up-to-date techniques for the successful development of drugs to treat central nervous system disorders. Despite increases in the number of individuals suffering from CNS-related disorders, the development and approval of drugs for their treatment have been hampered by inefficiencies in advancing compounds from preclinical discovery to the clinic. However, in the past decades, game-changing strides have been made in our understanding of the pathophysiology of CNS disorders and the relationship of drug exposure in plasma and CNS to pharmacodynamic measures in both animals and humans. Includes comprehensive coverage of biomarker tools and the role of personalized medicine in CNS drug development Discusses strategies for drug development for a full range of CNS indications, with particular attention to neuropsychiatric and neurocognitive disorders Includes chapters written by international experts from industry and academia

Translational Medicine in CNS Drug Development

Translational Medicine in CNS Drug Development
  • Author : George G. Nomikos,Douglas E. Feltner
  • Publisher : Academic Press
  • Release Date : 2019-06-18
  • Total pages : 458
  • ISBN : 0128031646
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Summary : Translational Medicine in CNS Drug Development, Volume 29, is the first book of its kind to offer a comprehensive overview of the latest developments in translational medicine and biomarker techniques. With extensive coverage on all aspects of biomarkers and personalized medicine, and numerous chapters devoted to the best strategies for developing ...

Translational Neuroimaging

Translational Neuroimaging
  • Author : Robert A. McArthur
  • Publisher : Academic Press
  • Release Date : 2012
  • Total pages : 421
  • ISBN : 0128031646
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Summary : With a unique collaborative approach of author teams from industry and academia, Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment provides an integrated perspective of small animal and human brain imaging in the development of translational models and biomarkers to understand human neuropsychiatric disorders and to accelerate the ...

Animal and Translational Models for CNS Drug Discovery Psychiatric Disorders

Animal and Translational Models for CNS Drug Discovery  Psychiatric Disorders
  • Author : Robert A. McArthur,Franco Borsini
  • Publisher : Academic Press
  • Release Date : 2008-10-20
  • Total pages : 528
  • ISBN : 0128031646
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Summary : Psychiatric Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders such as anxiety, obsessive-compulsive disorder, depression, schizophrenia, bipolar disorder, ADHD, and autistic spectrum disorder. Psychiatric Disorders has introductory chapters expressing the view of the ...

Neurotherapeutics in the Era of Translational Medicine

Neurotherapeutics in the Era of Translational Medicine
  • Author : Richard A. Smith,Brian K. Kaspar,Clive N. Svendsen
  • Publisher : Academic Press
  • Release Date : 2020-11-28
  • Total pages : 518
  • ISBN : 0128031646
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Summary : For the first time in history, there is now hope for treating neurological disorders that had previously been considered untreatable. The remarkable confluence of events that has heralded this is the focus of Neurotherapeutics in the Era of Translational Medicine. This anthology, written by many of the prominent scientists and ...

Animal and Translational Models for CNS Drug Discovery Psychiatric Disorders

Animal and Translational Models for CNS Drug Discovery  Psychiatric Disorders
  • Author : Robert A. McArthur,Franco Borsini
  • Publisher : Academic Press
  • Release Date : 2008-11-17
  • Total pages : 528
  • ISBN : 0128031646
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Summary : Psychiatric Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders such as anxiety, obsessive-compulsive disorder, depression, schizophrenia, bipolar disorder, ADHD, and autistic spectrum disorder. Psychiatric Disorders has introductory chapters expressing the view of the ...

Imaging in CNS Drug Discovery and Development

Imaging in CNS Drug Discovery and Development
  • Author : David Borsook,Lino R. Beccera,Edward Bullmore,Richard J. Hargreaves
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-03-10
  • Total pages : 396
  • ISBN : 0128031646
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Summary : Drug development today needs to balance agility, speed, and risk in defining probability of success for molecules, mechanisms, and therapeutic concepts. New techniques such as fMRI promise to be part of a sequence that could transform drug development. Although numerous review articles exist that discuss the use of imaging in ...

Translational Medicine and Drug Discovery

Translational Medicine and Drug Discovery
  • Author : Bruce H. Littman,Rajesh Krishna
  • Publisher : Cambridge University Press
  • Release Date : 2011-01-31
  • Total pages : 212
  • ISBN : 0128031646
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Summary : This book, edited by two innovative leaders in the field, focuses on the new discipline of translational medicine as it pertains to drug development within the pharmaceutical and biotechnology industry. Translational medicine seeks to translate biological and molecular knowledge of disease and how drugs work into innovative development strategies that ...

Animal and Translational Models for CNS Drug Discovery Neurological disorders

Animal and Translational Models for CNS Drug Discovery  Neurological disorders
  • Author : Robert A. McArthur,Franco Borsini
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 0128031646
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Summary : Read online Animal and Translational Models for CNS Drug Discovery Neurological disorders written by Robert A. McArthur,Franco Borsini, published by which was released on 2008. Download full Animal and Translational Models for CNS Drug Discovery Neurological disorders Books now! Available in PDF, ePub and Kindle....

Animal and Translational Models for CNS Drug Discovery Reward Deficit Disorders

Animal and Translational Models for CNS Drug Discovery  Reward Deficit Disorders
  • Author : Robert A. McArthur,Franco Borsini
  • Publisher : Academic Press
  • Release Date : 2009-02-24
  • Total pages : 432
  • ISBN : 0128031646
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Summary : Reward Deficit Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for reward deficit disorders such as alcohol dependence, nicotine dependence, heroin and cocaine addiction, obesity, and gambling and impulse control disorders. Reward Deficit Disorders has introductory ...

Drug Discovery Technology

Drug Discovery Technology
  • Author : Arjun Singh
  • Publisher : LAP Lambert Academic Publishing
  • Release Date : 2013
  • Total pages : 112
  • ISBN : 0128031646
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Summary : Drug Discovery Technology is versatile research area in the field of medicine, biotechnology, and pharmacology. Drug Discovery Technologies has been established to provide comprehensive overviews of all the major modern techniques, tools and technologies used in drug discovery and development technology. The major techniques and tools are used in drug ...

Animal and Translational Models for CNS Drug Discovery Reward deficit disorders

Animal and Translational Models for CNS Drug Discovery  Reward deficit disorders
  • Author : Robert A. McArthur,Franco Borsini
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 0128031646
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Summary : Read online Animal and Translational Models for CNS Drug Discovery Reward deficit disorders written by Robert A. McArthur,Franco Borsini, published by which was released on 2008. Download full Animal and Translational Models for CNS Drug Discovery Reward deficit disorders Books now! Available in PDF, ePub and Kindle....

Animal and Translational Models for CNS Drug Discovery 3 Vols Set

Animal and Translational Models for CNS Drug Discovery  3 Vols  Set
  • Author : Robert A. McArthur,Franco Borsini
  • Publisher : Unknown
  • Release Date : 2008-12
  • Total pages : 212
  • ISBN : 0128031646
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Summary : Read online Animal and Translational Models for CNS Drug Discovery 3 Vols Set written by Robert A. McArthur,Franco Borsini, published by which was released on 2008-12. Download full Animal and Translational Models for CNS Drug Discovery 3 Vols Set Books now! Available in PDF, ePub and Kindle....

Translational Medicine

Translational Medicine
  • Author : James Mittra,Christopher-Paul Milne
  • Publisher : CRC Press
  • Release Date : 2016-04-19
  • Total pages : 294
  • ISBN : 0128031646
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Summary : This book brings together a range of academic, industry and practitioner perspectives on translational medicine (TM). It enhances conceptual and practical understanding of the emergence and progress of the field and its potential impact on basic research, therapeutic development, and institutional infrastructure. In recognition of the various implications TM has ...

Animal and Translational Models for CNS Drug Discovery Neurological Disorders

Animal and Translational Models for CNS Drug Discovery  Neurological Disorders
  • Author : Robert A. McArthur,Franco Borsini
  • Publisher : Academic Press
  • Release Date : 2008-11-18
  • Total pages : 416
  • ISBN : 0128031646
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Summary : Neurological Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for neurological disorders such as neurofibromatosis, Alzheimer’s disease, Parkinson’s disease, Huntington disease, ALS, and the epilepsies. Neurological Disorders has introductory chapters expressing the view of ...

Translational Neuroimaging

Translational Neuroimaging
  • Author : Robert A. McArthur
  • Publisher : Academic Press
  • Release Date : 2012-10-05
  • Total pages : 464
  • ISBN : 0128031646
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Summary : Translational Neuroimaging: Tools for CNS Drug Discovery, Development and Treatment combines the experience of academic, clinical and industrial neuroimagers in a unique collaborative approach to provide an integrated perspective of the use of small animal and human brain imaging in developing and validating translational models and biomarkers for the study ...