Translational Glycobiology in Human Health and Disease

Written By Michelle Kilcoyne
Translational Glycobiology in Human Health and Disease
  • Publsiher : Academic Press
  • Release : 15 November 2020
  • ISBN : 9780128196557
  • Pages : 480 pages
  • Rating : /5 from reviews
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Download or read book entitled Translational Glycobiology in Human Health and Disease by author: Michelle Kilcoyne which was release on 15 November 2020 and published by Academic Press with total page 480 pages . This book available in PDF, EPUB and Kindle Format. Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role across a variety of disease types. As the biomedical sciences continue to adopt multi-omic and precision medicine approaches, a greater understanding of glycobiology is essential for maintaining healthy physiology and advancing disease treatment. Translational Glycobiology in Human Health and Disease offers a deep examination of glycobiology for experts and non-experts alike in areas ranging from the role of glycobiology in chronic and infectious diseases to advances in technologies for higher throughput analysis and diagnosis. While keeping human health in the forefront, this book integrates a thorough discussion of glycobiology fundamentals with its growing areas of application and societal impact. With emphasis throughout on the interdisciplinary nature of glycosciences, this book also features perspectives from the health, computational (glycoanalytics), materials, biopharmaceutical, and diagnostic sciences. Disease and speciality areas addressed include gycoimmunology, neuroglycobiology, commensal glycobiology, gut health, regenerative medicine and glycobiology, glycobiology and cancer, congenital disorders of glycosylation, infectious disease glycobiology, and parasite glycobiology. Computational approaches discussed, supporting the advance of new research, include advanced glycoanalytics, glycomics microarrays, glycoengineering, and glycol systems biology. Additionally, authors consider impact areas for society and public health, such as glycobiology and entrepreneurship, policy and regulatory requirements for glycosylation, future research, and translation to new diagnostics and drug discovery. Provides a deep, foundational overview of glycoscience and its translational potential, highlighting glycobiology's growing role in human health and disease study Examines a broad range of relevant disease areas and applications of glycobiology in policy and public health Features chapter contributions from leading, international experts in the field, fully integrating perspectives from the health, computational, materials, biopharmaceutical, and diagnostic sciencess

Translational Glycobiology in Human Health and Disease

Translational Glycobiology in Human Health and Disease
  • Author : Michelle Kilcoyne,Lokesh Joshi
  • Publisher : Academic Press
  • Release Date : 2020-11-15
  • Total pages : 480
  • ISBN : 9780128196557
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Summary : Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have ...

Progress in Molecular Biology and Translational Science

Progress in Molecular Biology and Translational Science
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-03-22
  • Total pages : 418
  • ISBN : 9780128196557
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Summary : Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A, Volume 162 in the Progress in Molecular Biology and Translational Science series provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include Glycan-based Biomarkers for Diagnosis ...

Post Translational Modifications in Health and Disease

Post Translational Modifications in Health and Disease
  • Author : Cecilio J. Vidal
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-10-13
  • Total pages : 490
  • ISBN : 9780128196557
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Summary : Post-translational modifications serve many different purposes in several cellular processes such as gene expression, protein folding and transport to appropriate cell compartment, protein-lipid and protein-protein interactions, enzyme regulation, signal transduction, cell proliferation and differentiation, protein stability, recycling and degradation. Although several-hundred different modifications are known, the significance of many of ...

Gangliosides in Health and Disease

Gangliosides in Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2018-04-25
  • Total pages : 480
  • ISBN : 9780128196557
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Summary : Gangliosides in Health and Disease, Volume 156, presents the latest information on Gangliosides, a class of glycolipids that are found on all vertebrate cell surfaces, and are particularly abundant in the brain. Individual chapters in this new volume cover Gangliosides as Toxin Receptors, Gangliosides in Cancer Cell Signaling, Gangliosides in inflammation ...

Genome Plasticity in Health and Disease

Genome Plasticity in Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-04-08
  • Total pages : 288
  • ISBN : 9780128196557
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Summary : Genome Plasticity in Health and Disease provides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific ...

Sialic Acids and Sialoglycoconjugates in the Biology of Life Health and Disease

Sialic Acids and Sialoglycoconjugates in the Biology of Life  Health and Disease
  • Author : Shyamasree Ghosh
  • Publisher : Academic Press
  • Release Date : 2020-01-08
  • Total pages : 362
  • ISBN : 9780128196557
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Summary : Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles ...

Gangliosides in Health and Disease

Gangliosides in Health and Disease
  • Author : Pablo H. H. Lopez
  • Publisher : Academic Press
  • Release Date : 2018-05
  • Total pages : 300
  • ISBN : 9780128196557
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Summary : Gangliosides in Health and Disease, Volume 154, presents the latest information on Gangliosides, a class of glycolipids that are found on all vertebrate cell surfaces, and are particularly abundant in the brain. Individual chapters in this new volume cover Gangliosides as Toxin Receptors, Gangliosides in Cancer Cell Signaling, Gangliosides in inflammation ...

Probing Glycosylation Using Azidosugars and the Staudinger Ligation in Vivo

Probing Glycosylation Using Azidosugars and the Staudinger Ligation in Vivo
  • Author : Danielle Hilda Dube
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 320
  • ISBN : 9780128196557
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Summary : Read online Probing Glycosylation Using Azidosugars and the Staudinger Ligation in Vivo written by Danielle Hilda Dube, published by which was released on 2005. Download full Probing Glycosylation Using Azidosugars and the Staudinger Ligation in Vivo Books now! Available in PDF, ePub and Kindle....

Microbiota in health and disease from pregnancy to childhood

Microbiota in health and disease  from pregnancy to childhood
  • Author : Pamela D. Browne,Eric Claassen,Michael D. Cabana
  • Publisher : Wageningen Academic Publishers
  • Release Date : 2017-07-20
  • Total pages : 344
  • ISBN : 9780128196557
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Summary : This book offers a state-of-the-art overview of the vital relationship between human microbiota and infant and child health. Renowned clinical-experimental experts in this field discuss the development of microbiota during early life and review the environmental inputs that affect the developing infant’s gut microbiota, such as early diet and (...

Lung Inflammation in Health and Disease Volume I

Lung Inflammation in Health and Disease  Volume I
  • Author : Yong-Xiao Wang
  • Publisher : Springer Nature
  • Release Date : 2021-05-02
  • Total pages : 409
  • ISBN : 9780128196557
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Summary : Respiratory diseases are leading causes of death and disability globally, with about 65 million people suffering from COPD, and 334 million from asthma, the most common chronic disease. Each year, tens of millions of people develop and can die from from respiratory infections such as pneumonia and TB. Systemic inflammation may induce ...

Glycosaminoglycans in Development Health and Disease

Glycosaminoglycans in Development  Health and Disease
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2010-10-28
  • Total pages : 408
  • ISBN : 9780128196557
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Summary : Glycosaminoglycans (GAGs) are a family of linear polysaccharides that are found in all animal tissues. Several are used as biomaterials, including heparin, heparin sulfate, keratan sulfate, dermatan sulfate, and chondroitin sulfate. This volume discusses the role of GAGs in development, health and disease. This series provides a forum for discussion ...

Proceedings of 3rd Glycobiology World Congress 2017

Proceedings of 3rd Glycobiology World Congress 2017
  • Author : ConferenceSeries
  • Publisher : ConferenceSeries
  • Release Date : 2021-07-25
  • Total pages : 79
  • ISBN : 9780128196557
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Summary : June 26-28, 2017 London, UK Key Topics : Glycoprotein Technologies, Glyco Bioinformatics, Glycans in Drug Design, Glyco Immunology, Glyco Biomarkers, Glycobiology and Biotechnology, Glycans in Diseases and Therapeutics, Glycobiology in Personalized Medicine, Glycans in Genetic Disorders, Glycobiology and Structural Biology, Glyco Proteomics, Glycomics and Metabolomics, Mass Spectrometry in Proteome Research, Glycobiology, Genomics ...

Myofilament Function in Health and Disease

Myofilament Function in Health and Disease
  • Author : Julien Ochala
  • Publisher : Frontiers Media SA
  • Release Date : 2017-05-22
  • Total pages : 212
  • ISBN : 9780128196557
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Summary : The present E-book, consisting of a compilation of original articles and reviews, presents how myofilaments are regulated in cardiac and skeletal muscles and trigger contraction. Additionally, this E-book gives insights into their dysregulation in a number of muscle disorders....

ATP gated P2X receptors in health and disease

ATP gated P2X receptors in health and disease
  • Author : Andrea Nistri,Geoffrey Burnstock,Baljit S Khakh,Rashid Giniatullin
  • Publisher : Frontiers Media SA
  • Release Date : 2015-01-05
  • Total pages : 212
  • ISBN : 9780128196557
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Summary : Extracellular ATP is currently recognized as one of the most widely distributed neurotransmitters and neuromodulators in the peripheral and central nervous system. ATP-gated P2X receptors are expressed by neurons, glial and many other non-neuronal cells and represent an attractive target for therapeutic interventions. Diverse molecular and cellular mechanisms have ...

Sialobiology Structure Biosynthesis and Function Sialic Acid Glycoconjugates in Health and Disease

Sialobiology  Structure  Biosynthesis and Function  Sialic Acid Glycoconjugates in Health and Disease
  • Author : Joe Tiralongo,Ivan Martinez-Duncker
  • Publisher : Bentham Science Publishers
  • Release Date : 2013-02-13
  • Total pages : 531
  • ISBN : 9780128196557
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Summary : This ebook presents a summary of central aspects of sialobiology (i.e., the study of sialic acid and its relevance to biology). The importance of substitution by the sugar sialic acid and the role played by sialylated structures (eg. glycoproteins, glycolipids, glycoconjugates) in immune recognition, neural cell growth, embryogenesis and ...