The Orexin Hypocretin System

Written By Seiji Nishino
The Orexin Hypocretin System
  • Publsiher : Springer Science & Business Media
  • Release : 22 November 2007
  • ISBN : 1592599508
  • Pages : 416 pages
  • Rating : /5 from reviews
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Download or read book entitled The Orexin Hypocretin System by author: Seiji Nishino which was release on 22 November 2007 and published by Springer Science & Business Media with total page 416 pages . This book available in PDF, EPUB and Kindle Format. Impairment of orexin/hypocretin signaling causes narcolepsy-cataplexy in animals and humans. Most human narcolepsy-cataplexy cases are associated with orexin/hypocretin ligand deficiency, which can be detected clinically using cerebrospinal orexin/hypocretin measures and may lead to future treatments with orexin/hypocretin replacement therapy. In The Orexin/Hypocretin System: Physiology and Pathophysiology, leading researchers and clinicians review these exciting developments to set the stage for further research on the loss of orexin/hypocretin neurons in humans, regulation of sleep and wakefulness by the orexin/hypocretin system, and the role of the orexin/hypocretin system in many other physiological processes, including feeding, autonomic regulation, and neuroendocrine regulation. Topics of interest include an assessment of the functions and the physiology of orexin/hypocretin, its pathophysiology in human narcolepsy-cataplexy, and possible pharmacological treatments. The authors also introduce several experimental methods for orexin/hypocretin research, and, using multidisciplinary approaches, explain their uses and limitations. Authoritative and state-of-the-art, The Orexin/Hypocretin System: Physiology and Pathophysiology will aid scientists in the search for novel bioactive peptides and their receptors, as well as novel physiological insights and opportunities for the clinical treatment of not only narcolepsy, but also a broad range of diseases associated with endocrine, feeding, and body weight regulation.

The Orexin Hypocretin System

The Orexin Hypocretin System
  • Author : Seiji Nishino,Takeshi Sakurai
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-22
  • Total pages : 416
  • ISBN : 1592599508
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Summary : Impairment of orexin/hypocretin signaling causes narcolepsy-cataplexy in animals and humans. Most human narcolepsy-cataplexy cases are associated with orexin/hypocretin ligand deficiency, which can be detected clinically using cerebrospinal orexin/hypocretin measures and may lead to future treatments with orexin/hypocretin replacement therapy. In The Orexin/Hypocretin System: Physiology and ...

The Orexin Hypocretin System

The Orexin Hypocretin System
  • Author : Jim R. Fadel,Joshua A. Burk
  • Publisher : Academic Press
  • Release Date : 2019-01-03
  • Total pages : 188
  • ISBN : 1592599508
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Summary : The Orexins/Hypocretins System: Functional Roles and Therapeutic Potential summarizes research on both the physiological functioning of orexins, their impact on homeostatic processes, and related disorders. The book encompasses the effects on appetite, sleep, substance abuse, cognition, and anxiety. Additionally, it examines new therapeutic approaches utilizing orexins, including utilization of ...

The Orexin hypocretin System

The Orexin hypocretin System
  • Author : Anantha Shekhar
  • Publisher : Elsevier
  • Release Date : 2012
  • Total pages : 196
  • ISBN : 1592599508
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Summary : "In The Orexin/Hypocretin System: Physiology and Pathophysiology, leading researchers and clinicians set the stage for further research on the loss of orexin/hypocretin neurons in humans, regulation of sleep and wakefulness by the orexin/hypocretin system, and the role of the orexin/hypocretin system in many other physiological processes, ...

The Role of the Orexin hypocretin System in the Incubation of Alcohol Craving in Rats

The Role of the Orexin hypocretin System in the Incubation of Alcohol Craving in Rats
  • Author : Olivia Gilman Mallari
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 73
  • ISBN : 1592599508
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Summary : Read online The Role of the Orexin hypocretin System in the Incubation of Alcohol Craving in Rats written by Olivia Gilman Mallari, published by which was released on 2016. Download full The Role of the Orexin hypocretin System in the Incubation of Alcohol Craving in Rats Books now! Available in PDF, ...

Involvement of the Orexin hypocretin System in Ethanol conditioned Behavior

Involvement of the Orexin hypocretin System in Ethanol conditioned Behavior
  • Author : Charlene M. Voorhees
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 50
  • ISBN : 1592599508
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Summary : Read online Involvement of the Orexin hypocretin System in Ethanol conditioned Behavior written by Charlene M. Voorhees, published by which was released on 2009. Download full Involvement of the Orexin hypocretin System in Ethanol conditioned Behavior Books now! Available in PDF, ePub and Kindle....

Neural Circuit Modelling of the Orexin Hypocretin System with Implications for Clinical Depression

Neural Circuit Modelling of the Orexin Hypocretin System with Implications for Clinical Depression
  • Author : Alok Joshi
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 212
  • ISBN : 1592599508
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Summary : Read online Neural Circuit Modelling of the Orexin Hypocretin System with Implications for Clinical Depression written by Alok Joshi, published by which was released on 2014. Download full Neural Circuit Modelling of the Orexin Hypocretin System with Implications for Clinical Depression Books now! Available in PDF, ePub and Kindle....

Behavioral Neuroscience of Orexin Hypocretin

Behavioral Neuroscience of Orexin Hypocretin
  • Author : Andrew J Lawrence,Luis de Lecea
  • Publisher : Springer
  • Release Date : 2017-05-29
  • Total pages : 322
  • ISBN : 1592599508
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Summary : This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely ...

Role of REM Sleep Melanin Concentrating Hormone and Orexin hypocretin Systems in Ischemic Stroke

Role of REM Sleep  Melanin Concentrating Hormone and Orexin hypocretin Systems in Ischemic Stroke
  • Author : Marta Pace
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 212
  • ISBN : 1592599508
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Summary : Read online Role of REM Sleep Melanin Concentrating Hormone and Orexin hypocretin Systems in Ischemic Stroke written by Marta Pace, published by which was released on 2016. Download full Role of REM Sleep Melanin Concentrating Hormone and Orexin hypocretin Systems in Ischemic Stroke Books now! Available in PDF, ePub and Kindle....

G Protein Activation and Acetylcholine Release Stimulated by Hypocretin in the Rat Pons

G Protein Activation and Acetylcholine Release Stimulated by Hypocretin in the Rat Pons
  • Author : René Bernard
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 212
  • ISBN : 1592599508
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Summary : Read online G Protein Activation and Acetylcholine Release Stimulated by Hypocretin in the Rat Pons written by René Bernard, published by which was released on 2005. Download full G Protein Activation and Acetylcholine Release Stimulated by Hypocretin in the Rat Pons Books now! Available in PDF, ePub and Kindle....

Neurology in clinical practice

Neurology in clinical practice
  • Author : W. G. Bradley
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 1592599508
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Summary : Read online Neurology in clinical practice written by W. G. Bradley, published by which was released on 2008. Download full Neurology in clinical practice Books now! Available in PDF, ePub and Kindle....

Insomnia and beyond Exploring the therapeutic potential of orexin receptor antagonists

Insomnia and beyond   Exploring the therapeutic potential of orexin receptor antagonists
  • Author : Michel Alexander Steiner,Christopher J Winrow
  • Publisher : Frontiers E-books
  • Release Date : 2014-11-11
  • Total pages : 212
  • ISBN : 1592599508
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Summary : Orexin/hypocretin neuropeptides, produced by a few thousand neurons in the lateral hypothalamus, are of critical importance for the control of vigilance and arousal of vertebrates, from fish to amphibians, birds and mammals. Two orexin peptides, called orexin-A and orexin-B, exist in mammals. They bind with different affinities to two ...

The Orexin System

The Orexin System
  • Author : Michel Steiner,Masashi Yanagisawa,Martine Clozel
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2021
  • Total pages : 212
  • ISBN : 1592599508
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Summary : "Discovered in 1998, the orexin system lies at the core of the sleep and wake state regulation inside our brain. This book summarizes recent research, ideas and perspectives from some of the most influential researchers in the fields of hypocretin/orexin and sleep. For example, it explains the intricate role of ...

Orexin and Sleep

Orexin and Sleep
  • Author : Takeshi Sakurai,S.R. Pandi-Perumal,Jaime M. Monti
  • Publisher : Springer
  • Release Date : 2015-09-22
  • Total pages : 410
  • ISBN : 1592599508
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Summary : This volume is intended for neuropharmacologists, psychopharmacologists, pharmacologists, pharmacists, sleep researchers, translational neuroscience researchers, and other basic researchers and clinical scientists interested in an interdisciplinary approach to sleep medicine. The level of the book is aiming at CNS researchers, drug development scientists, basic and clinical sleep researchers, as well as ...

Principles of Drug Therapy in Neurology

Principles of Drug Therapy in Neurology
  • Author : Michael V. Johnston,Robert Gross
  • Publisher : Oxford University Press
  • Release Date : 2008-05
  • Total pages : 558
  • ISBN : 1592599508
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Summary : Since the first edition of this book was published in 1992, the number of pharmacological therapies available for treating neurological disorders has grown exponentialy. This new edition brings the book fully up-to-date, and features PET scans to illustrate brain action, and new chapters on practical therapeutics and clinical trials....

Functional Neuroanatomy Text and Atlas 2nd Edition

Functional Neuroanatomy  Text and Atlas  2nd Edition
  • Author : Adel K. Afifi,Ronald A. Bergman
  • Publisher : McGraw Hill Professional
  • Release Date : 2005-02-18
  • Total pages : 550
  • ISBN : 1592599508
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Summary : A Doody's Core Title Superbly illustrated, this core textbook reinforces an understanding of basic neuroanatomical structures by emphasizing their clinical significance in neurologic disease. Featuring a seamless integration of over 400 illustrations within the text, Functional Neuroanatomy includes cross-sectional atlas views of the brain and brain stem, MRI images in three ...