The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

Written By Joerg Bluemel
The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
  • Publsiher : Academic Press
  • Release : 12 March 2015
  • ISBN : 9780124171442
  • Pages : 716 pages
  • Rating : /5 from reviews
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Download or read book entitled The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment by author: Joerg Bluemel which was release on 12 March 2015 and published by Academic Press with total page 716 pages . This book available in PDF, EPUB and Kindle Format. Annotation This reference compiles the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, it provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing.

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
  • Author : Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard F. Weinbauer
  • Publisher : Academic Press
  • Release Date : 2015-03-12
  • Total pages : 716
  • ISBN : 9780124171442
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Summary : Annotation This reference compiles the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, it ...

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment

The Nonhuman Primate in Nonclinical Drug Development and Safety Assessment
  • Author : Joerg Bluemel,Sven Korte,Emanuel Schenck,Gerhard Weinbauer
  • Publisher : Academic Press
  • Release Date : 2015-03-13
  • Total pages : 716
  • ISBN : 9780124171442
GET BOOK

Summary : The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, ...

Challenges in Nonhuman Primate Research in the 21st Century

Challenges in Nonhuman Primate Research in the 21st Century
  • Author : Gerhard F. Weinbauer,Friedhelm Vogel
  • Publisher : Waxmann Verlag
  • Release Date : 2013
  • Total pages : 180
  • ISBN : 9780124171442
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Summary : In continuation of the Covance Primate Symposium Series, the 19th Covance Primate Symposium took place in Münster on 23rd & 24th of May 2012. Altogether, 70 participants representing 43 organisations, gathered for this symposium. The 2012 Primate Symposium focussed on ?Challenges in Nonhuman Primate Research in the 21st Century?. The broad participation and the ...

Drug Discovery Toxicology

Drug Discovery Toxicology
  • Author : Yvonne Will,J. Eric McDuffie,Andrew J. Olaharski,Brandon D. Jeffy
  • Publisher : John Wiley & Sons
  • Release Date : 2016-03-22
  • Total pages : 584
  • ISBN : 9780124171442
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Summary : As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process. • Guides researchers as to what drug safety experiments are both practical and useful • Covers ...

Model Organisms for Microbial Pathogenesis Biofilm Formation and Antimicrobial Drug Discovery

Model Organisms for Microbial Pathogenesis  Biofilm Formation and Antimicrobial Drug Discovery
  • Author : Busi Siddhardha,Madhu Dyavaiah,Asad Syed
  • Publisher : Springer Nature
  • Release Date : 2020-03-28
  • Total pages : 684
  • ISBN : 9780124171442
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Summary : This book provides essential insights into microbial pathogenesis, host-pathogen interactions, and the anti-microbial drug resistance of various human pathogens on the basis of various model organisms. The initial sections of the book introduce readers to the mechanisms of microbial pathogenesis, host-pathogen interactions, anti-microbial drug resistance, and the dynamics of biofilm ...

The Laboratory Nonhuman Primate

The Laboratory Nonhuman Primate
  • Author : Jeffrey D. Fortman,Terry A. Hewett,Lisa C. Halliday
  • Publisher : CRC Press
  • Release Date : 2017-10-23
  • Total pages : 366
  • ISBN : 9780124171442
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Summary : Extensively updated to include current literature, The Laboratory Nonhuman Primate, Second Edition, continues to serve as a quick reference source for technicians, caretakers, veterinarians, researchers, and students working with primates in biomedical research. It provides details on basic husbandry and covers biologic characteristics, regulatory compliance, common diseases, and anesthetic management. ...

Drug Safety Evaluation

Drug Safety Evaluation
  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release Date : 2016-12-01
  • Total pages : 918
  • ISBN : 9780124171442
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Summary : This practical guide presents a road map for safety assessment as an integral part of the development of new drugs and therapeutics. Helps readers solve scientific, technical, and regulatory issues in preclinical safety assessment and early clinical drug development Explains scientific and philosophical bases for evaluation of specific concerns – including ...

Toxicologic Pathology for Non Pathologists

Toxicologic Pathology for Non Pathologists
  • Author : Thomas J. Steinbach,Daniel J. Patrick,Mary Ellen Cosenza
  • Publisher : Springer Nature
  • Release Date : 2019-10-31
  • Total pages : 919
  • ISBN : 9780124171442
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Summary : This extensive volume began as a short course primarily geared toward toxicologists who want to expand their understanding of toxicologic pathology in order to be better study directors while also proving to be of great interest to other drug development scientists and regulatory reviewers. The overall goal is to help ...

Immunotoxicology Strategies for Pharmaceutical Safety Assessment

Immunotoxicology Strategies for Pharmaceutical Safety Assessment
  • Author : Danuta J. Herzyk,Jeanine L. Bussiere
  • Publisher : John Wiley & Sons
  • Release Date : 2008-11-21
  • Total pages : 336
  • ISBN : 9780124171442
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Summary : An important reference which provides an overview of the current and recently introduced methodologies for testing the immunotoxic risks in drug candidates Helps readers understand the significance of the methods and approaches to immunotoxicology testing Aids drug scientists in industry and regulatory areas to consolidate approaches to immunotox testing Offers ...

Preclinical Safety Evaluation of Biopharmaceuticals

Preclinical Safety Evaluation of Biopharmaceuticals
  • Author : Joy A. Cavagnaro
  • Publisher : John Wiley & Sons
  • Release Date : 2013-03-07
  • Total pages : 1064
  • ISBN : 9780124171442
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Summary : "The goal is to provide a comprehensive reference book for thepreclinicaldiscovery and development scientist whoseresponsibilities span target identification, lead candidateselection, pharmacokinetics, pharmacology, and toxicology, and forregulatory scientists whose responsibilities include the evaluationof novel therapies." —From the Afterword by Anthony D. Dayan Proper preclinical safety evaluation can improve the predictivevalue, lessen ...

An Introduction to Interdisciplinary Toxicology

An Introduction to Interdisciplinary Toxicology
  • Author : Carey N. Pope,Jing Liu
  • Publisher : Academic Press
  • Release Date : 2020-02-18
  • Total pages : 644
  • ISBN : 9780124171442
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Summary : An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from “simple molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, ...

Essentials of Laboratory Animal Science Principles and Practices

Essentials of Laboratory Animal Science  Principles and Practices
  • Author : P. Nagarajan,Ramachandra Gudde,Ramesh Srinivasan
  • Publisher : Springer Nature
  • Release Date : 2021-08-24
  • Total pages : 806
  • ISBN : 9780124171442
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Summary : This book comprehensively reviews the anatomy, physiology, genetics and pathology of laboratory animals as well as the principles and practices of using laboratory animals for biomedical research.It covers the design of buildings used for laboratory animals, quality control of laboratory animals, and toxicology, and discusses various animal models used ...

Toxicology of the Gastrointestinal Tract Second Edition

Toxicology of the Gastrointestinal Tract  Second Edition
  • Author : Shayne Cox Gad
  • Publisher : CRC Press
  • Release Date : 2018-10-26
  • Total pages : 464
  • ISBN : 9780124171442
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Summary : The gastrointestinal tract is the most important of the three major routes of entry (and clearance) of xenobiotics and biologic entities into the bodies of mammals. As such, it is also the major route for administration of pharmaceuticals to humans. Gastrointestinal Toxicology, Second Edition describes the mechanism for entry and ...

Veterinary Ophthalmology

Veterinary Ophthalmology
  • Author : Kirk N. Gelatt,Gil Ben-Shlomo,Brian C. Gilger,Diane V. H. Hendrix,Thomas J. Kern,Caryn E. Plummer
  • Publisher : John Wiley & Sons
  • Release Date : 2021-02-09
  • Total pages : 2752
  • ISBN : 9780124171442
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Summary : Offering the very latest in diagnostics and therapeutics, this book presents a fully updated and revised edition of the definitive reference to veterinary ophthalmology. Covering both basic sciences and clinical treatment, it is a state-of-the-art text that encompasses ophthalmology in all species, including dogs, cats, horses, large animals, and exotic ...

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

A Comprehensive Guide to Toxicology in Nonclinical Drug Development
  • Author : Ali S. Faqi
  • Publisher : Academic Press
  • Release Date : 2016-11-03
  • Total pages : 986
  • ISBN : 9780124171442
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Summary : A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem ...