Description : What do you do when you find a stranger in your closet and she can disappear and reappear at whim? What if she then tells you that her body is actually in a coma on the other side of town? What starts off as a dilemma that Arthur is faced with when he discovers Lauren in his apartment, becomes a heartwarming love story.
Description : During World War II at least 13.5 million people were employed as forced labourers in Germany and across the territories occupied by the German Reich. Most came from Russia, Ukraine, Belarus, Moldavia, the Baltic countries, France, Poland and Italy. Among them were 8.4 million civilians working for private companies and public agencies in industry, administration and agriculture. In addition, there were 4.6 million prisoners of war and 1.7 million concentration camp prisoners who were either subjected to forced labour in concentration or similar camps or were 'rented out' or sold by the SS. While there are numerous publications on forced labour in National Socialist Germany during World War II, this publication combines a historical account of events with the biographies and memories of former forced labourers from twenty-seven countries, offering a comparative international perspective.
Description : Macrophages were initially identified as a key element in the innate host response to infection and injury due to their phagocytic clearance and elimination of pathogenic and non-pathogenic entities. However, as macrophage research advanced it became clear that not only are these cells amenable to the acquisition of multiple plastic phenotypes during inflammatory responses to different pathogens, they also play a paramount role in the termination of inflammation and acquired immune responses. In addition, macrophages profoundly affect host physiology when they migrate to distant sites and differentiate to specialized cells, like foam cells, osteoclasts, adipose tissue- and tumor -associated macrophages and other macrophage-derived cell types. These processes are affected by the inflammation-resolution axis and can result in health threats, such as atherosclerosis, bone loss, obesity, fibrosis and cancer. This Research Topic issue will cover a wide range of topics in macrophage biology: 1. Macrophages in immune responses to pathogens 2. Macrophages in the termination of acute and acquired immunity. 3. The role of macrophages and their descendents in inflammation-associated pathologies. 4. Macrophage polarization and differentiation. Particular focus will be given to the modulation of macrophage phenotype and function following their encounter with apoptotic cells and the signaling cascades that govern these changes.