TDP 43 and Neurodegeneration

Written By Vijay Kumar
TDP 43 and Neurodegeneration
  • Publsiher : Academic Press
  • Release : 01 June 2021
  • ISBN : 0128204400
  • Pages : 300 pages
  • Rating : /5 from reviews
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Download or read book entitled TDP 43 and Neurodegeneration by author: Vijay Kumar which was release on 01 June 2021 and published by Academic Press with total page 300 pages . This book available in PDF, EPUB and Kindle Format. Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders. Reviews TDP-43 structure, folding, function, and pathology Identifies TDP-43 role in ALS, FTP, and other neurodegenerative diseases Presents a systems and precision biology perspective of TDP-43 Discusses therapeutics of TDP-43 proteinopathies Translates bench research to application bedside

TDP 43 and Neurodegeneration

TDP 43 and Neurodegeneration
  • Author : Vijay Kumar,Manoj Kumar Jaiswal
  • Publisher : Academic Press
  • Release Date : 2021-06-01
  • Total pages : 300
  • ISBN : 0128204400
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Summary : Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s ...

Advanced Understanding of Neurodegenerative Diseases

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  • Publisher : BoD – Books on Demand
  • Release Date : 2011-12-16
  • Total pages : 456
  • ISBN : 0128204400
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Summary : Advanced Understanding of Neurodegenerative Diseases focuses on different types of diseases, including Alzheimer's disease, frontotemporal dementia, different tauopathies, Parkinson's disease, prion disease, motor neuron diseases such as multiple sclerosis and spinal muscular atrophy. This book provides a clear explanation of different neurodegenerative diseases with new concepts of understand the etiology, ...

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Stem Cell Therapy for Organ Failure
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  • Publisher : Springer
  • Release Date : 2015-01-02
  • Total pages : 278
  • ISBN : 0128204400
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Summary : The book “STEM CELL THERAPY FOR ORGAN FAILURES” edited by Dr. S. Indumathi demonstrates the In Vitro and In vivo therapeutic strategies and applications of pre- and post-natal stem cells for treating the failures of various organ systems of our body in a wide perspective. It explores the past, present ...

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  • Author : Uddin, Md. Sahab,Amran, Md. Shah
  • Publisher : IGI Global
  • Release Date : 2018-07-31
  • Total pages : 597
  • ISBN : 0128204400
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Summary : Neurodegeneration is a key feature of several diseases that are referred to as neurodegenerative diseases. The process of neurodegeneration is not well-understood so the diseases that stem from it have, as yet, no cures. As such, studying the effects of these disorders can provide insight into the treatment, prevention, and ...

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Geriatric Neurology
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2019-12-18
  • Total pages : 616
  • ISBN : 0128204400
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Summary : Geriatric Neurology, Volume 167, serves as an update on the basic biological and behavioral mechanisms underlying the aging process, with an emphasis on neurological aging and state-of-the-art reviews on our understanding of vascular, cognitive, neurodegenerative and neuropsychiatric diseases in the elderly. Developed with an eye to providing both the basic underpinnings ...

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  • Publisher : Springer Nature
  • Release Date : 2020
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  • ISBN : 0128204400
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Summary : This translational, clinically oriented book describes in detail novel approaches to cancer immunotherapy, current strategies to target tumor immunosuppression, and prognostic biomarkers for personalized cancer treatments. Since the first, very successful edition of the book was published in 2015, the original chapters have been significantly updated and entirely new chapters are ...