Stem Cell Manufacturing

Written By Joaquim M. S. Cabral
Stem Cell Manufacturing
  • Publsiher : Elsevier
  • Release : 24 July 2016
  • ISBN : 0444632662
  • Pages : 340 pages
  • Rating : /5 from reviews
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Download or read book entitled Stem Cell Manufacturing by author: Joaquim M. S. Cabral which was release on 24 July 2016 and published by Elsevier with total page 340 pages . This book available in PDF, EPUB and Kindle Format. Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the therapeutic potential of stem cells and their derivatives and increased the awareness of the public and scientific community for the topic. The successful manufacturing of stem cells and their derivatives is expected to have a positive impact in the society since it will contribute to widen the offer of therapeutic solutions to the patients. Fully defined cellular products can be used to restore the structure and function of damaged tissues and organs and to develop stem cell-based cellular therapies for the treatment of cancer and hematological disorders, autoimmune and other inflammatory diseases and genetic disorders. Presents the first ‘Flowchart‘ of stem cell manufacturing enabling easy understanding of the various processes in a sequential and coherent manner Covers all bioprocess technologies required for the transfer of the bench findings to the clinic including the process components: cell signals, bioreactors, modeling, automation, safety, etc. Presents comprehensive coverage of a true multidisciplinary topic by bringing together specialists in their particular area Provides the basics of the processes and identifies the issues to be resolved for large scale cell culture by the bioengineer Addresses the critical need in bioprocessing for the successful delivery of stem cell technology to the market place by involving professional engineers in sections of the book

Stem Cell Manufacturing

Stem Cell Manufacturing
  • Author : Joaquim M. S. Cabral,Claudia Lobato da Silva,Lucas G. Chase,Maria Margarida Diogo
  • Publisher : Elsevier
  • Release Date : 2016-07-24
  • Total pages : 340
  • ISBN : 0444632662
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Summary : Stem Cell Manufacturing discusses the required technologies that enable the transfer of the current laboratory-based practice of stem cell tissue culture to the clinic environment as therapeutics, while concurrently achieving control, reproducibility, automation, validation, and safety of the process and the product. The advent of stem cell research unveiled the ...

Novel Perspectives of Stem Cell Manufacturing and Therapies

Novel Perspectives of Stem Cell Manufacturing and Therapies
  • Author : Diana Kitala,Ana Colette Maurício
  • Publisher : BoD – Books on Demand
  • Release Date : 2021-04-14
  • Total pages : 178
  • ISBN : 0444632662
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Summary : In the 1950s, Nobel Prize winner Dr. E. Donnall Thomas was the first to successfully transplant hematopoietic stem cells. Since then, studies on stem cells have evolved and expanded worldwide. There are more than 650,000 scientific publications on stem cells and more than 8000 stem cell clinical trials. This book summarizes types ...

Stem Cells and Good Manufacturing Practices

Stem Cells and Good Manufacturing Practices
  • Author : Kursad Turksen
  • Publisher : Humana
  • Release Date : 2021-04-01
  • Total pages : 288
  • ISBN : 0444632662
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Summary : This detailed book explores the utilization and delivery of stem cells for therapeutic purposes in patients in the clinic and the tightly controlled Good Manufacturing Practices (GMP) that make these powerful techniques possible. Fully updated and expanded from the first edition, this collection features a new set of protocols to ...

Stem Cells and Cell Therapy

Stem Cells and Cell Therapy
  • Author : Mohamed Al-Rubeai,Mariam Naciri
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-10-01
  • Total pages : 189
  • ISBN : 0444632662
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Summary : With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies ...

Stem Cell Bioprocessing and Manufacturing

Stem Cell Bioprocessing and Manufacturing
  • Author : Joaquim M. S. Cabral,Cláudia Lobato da Silva,Maria Margarida Diogo
  • Publisher : MDPI
  • Release Date : 2021-01-20
  • Total pages : 170
  • ISBN : 0444632662
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Summary : The next healthcare revolution will apply regenerative medicines using human cells and tissues. The aim of the regenerative medicine approach is to create biological therapies or substitutes in vitro for the replacement or restoration of tissue function in vivo lost through failure or disease. However, whilst science has revealed the ...

Mesenchymal Stem Cell Manufacturing for Clinical Use

Mesenchymal Stem Cell Manufacturing for Clinical Use
  • Author : Franca Fagioli
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 212
  • ISBN : 0444632662
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Summary : Mesenchymal stromal/stem cells (MSCs) are adult, self-renewable, multipotent cells that can be isolated in various tissues, most commonly bone marrow (BM) and adipose tissue. Because of their capacity for self-renewal and differentiation into tissues of mesodermal origin and due to their immunomodulatory ability, MSCs are used in many preclinical ...

Perinatal Stem Cells

Perinatal Stem Cells
  • Author : Zhong Chao Han,Tsuneo A. Takahashi,Zhibo Han,Zongjin Li
  • Publisher : Springer
  • Release Date : 2019-04-06
  • Total pages : 173
  • ISBN : 0444632662
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Summary : This book provides a comprehensive introduction to various types of perinatal stem cells. Given their unique regenerative abilities, stem cells offer a promising avenue in the treatment of degenerative diseases or injury. Currently, the limitations of postnatal cell sources and expanding efficiency may limit autologous stem cell therapies. Although embryonic ...

Mesenchymal Stromal Cells

Mesenchymal Stromal Cells
  • Author : Hematti Peiman,Sowmya Viswanathan
  • Publisher : Academic Press
  • Release Date : 2016-08-11
  • Total pages : 362
  • ISBN : 0444632662
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Summary : Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique ...

Perinatal Tissue Derived Stem Cells

Perinatal Tissue Derived Stem Cells
  • Author : Babak Arjmand
  • Publisher : Springer
  • Release Date : 2016-12-01
  • Total pages : 239
  • ISBN : 0444632662
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Summary : This book covers several aspects of perinatal tissue-derived stem cells, from theoretical concepts to clinical applications. Topics include functions and different sources, immunomodulatory properties, translational point of view, GMP facility design and manufacturing for clinical translation, therapeutic potentials, and finally ethical considerations. The text provides a brief review of each ...

Stem Cells and Cell Therapy

Stem Cells and Cell Therapy
  • Author : Mohamed Al-Rubeai,Mariam Naciri
  • Publisher : Springer
  • Release Date : 2013-10-15
  • Total pages : 189
  • ISBN : 0444632662
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Summary : With the discovery of stem cells capable of multiplying indefinitely in culture and differentiating into many other cell types in appropriate conditions, new hopes were born in repair and replacement of damaged cells and tissues. The features of stem cells may provide treatment for some incurable diseases with some therapies ...

Bioreactors for Stem Cell Expansion and Differentiation

Bioreactors for Stem Cell Expansion and Differentiation
  • Author : Joaquim M.S. Cabral,Claudia Lobato da Silva
  • Publisher : CRC Press
  • Release Date : 2018-09-03
  • Total pages : 334
  • ISBN : 0444632662
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Summary : An international team of investigators presents thought-provoking reviews of bioreactors for stem cell expansion and differentiation and provides cutting-edge information on different bioreactor systems. The authors offer novel insights into bioreactor-based culture systems specific for tissue engineering, including sophisticated and cost-effective manufacturing strategies geared to overcome technological shortcomings that currently ...

Perinatal Stem Cells

Perinatal Stem Cells
  • Author : Anthony Atala,Sean V. Murphy
  • Publisher : Springer
  • Release Date : 2014-08-28
  • Total pages : 373
  • ISBN : 0444632662
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Summary : This comprehensive volume is one of the first books to offer the reader detailed insight into sources of perinatal stem cells, their biology, and their potential for disease treatment. It examines the research and therapeutic applications of perinatal stem cells including the treatment of renal disease, hematopoietic regeneration, cardiac disease, ...

Advances In Pharmaceutical Cell Therapy Principles Of Cell based Biopharmaceuticals

Advances In Pharmaceutical Cell Therapy  Principles Of Cell based Biopharmaceuticals
  • Author : Huss Ralf,Guenther Christine,Hauser Andrea Josefine
  • Publisher : World Scientific
  • Release Date : 2015-09-23
  • Total pages : 564
  • ISBN : 0444632662
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Summary : This textbook is a comprehensive overview of the development of cell-based biopharmaceuticals. Beginning with the underlying biology of stem cell and cell-based products, it traces the long and complex journey from preclinical concept to initiation of a pivotal clinical trial and the potential business model behind it.The book also ...

Stem Cells in Regenerative Medicine

Stem Cells in Regenerative Medicine
  • Author : Alain A. Vertes,Nasib Qureshi,Arnold I. Caplan,Lee E. Babiss
  • Publisher : John Wiley & Sons
  • Release Date : 2015-12-02
  • Total pages : 776
  • ISBN : 0444632662
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Summary : This book is a unique guide to emerging stem cell technologies and the opportunities for their commercialisation. It provides in-depth analyses of the science, business, legal, and financing fundamentals of stem cell technologies, offering a holistic assessment of this emerging and dynamic segment of the field of regenerative medicine. • Reviews ...

Cell Therapy

Cell Therapy
  • Author : Adrian Gee
  • Publisher : Springer
  • Release Date : 2021-07-25
  • Total pages : 212
  • ISBN : 0444632662
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Summary : This new edition presents a fully-updated and expanded look at current Good Manufacturing Practice (cGMP) for cell therapy products. It provides a complete discussion of facility design and operation including details specific to cord blood banking, cell processing, vector production and qualification of a new facility. Several chapters cover facility ...