Recent Advances in iPSC Disease Modeling Volume 1

Written By ALEXANDER BIRBRAIR
Recent Advances in iPSC Disease Modeling  Volume 1
  • Publsiher : Academic Press
  • Release : 16 July 2020
  • ISBN : 0128232692
  • Pages : 320 pages
  • Rating : /5 from reviews
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Download or read book entitled Recent Advances in iPSC Disease Modeling Volume 1 by author: ALEXANDER BIRBRAIR which was release on 16 July 2020 and published by Academic Press with total page 320 pages . This book available in PDF, EPUB and Kindle Format. Recent Advances in iPSC Disease Modeling, Volume 1 addresses how induced pluripotent stem cells can be used to model various diseases. Somatic cells are reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. This volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to model several diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. Further insights into these mechanisms will have important implications for our understanding of disease appearance, development, and progression. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues, and organs using state-of-art techniques. These advantages facilitated identification of key targets and definition of the molecular basis of several disorders. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine, and therapeutics Covers the following diseases: severe congenital neutropenia, sickle cell and Diamond-Blackfan anemias, muscular dystrophies, Bernard-Soulier syndrome, familial hypercholesterolemia type II A, Werner syndrome, lysosomal storage diseases, and more Contains description of cutting-edge research on the development of disease-specific human pluripotent stem cells. These cells allow us to study cellular and molecular processes involved in several human diseases

Recent Advances in iPSC Disease Modeling Volume 1

Recent Advances in iPSC Disease Modeling  Volume 1
  • Author : ALEXANDER BIRBRAIR
  • Publisher : Academic Press
  • Release Date : 2020-07-16
  • Total pages : 320
  • ISBN : 0128232692
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Summary : Recent Advances in iPSC Disease Modeling, Volume 1 addresses how induced pluripotent stem cells can be used to model various diseases. Somatic cells are reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. This volume teaches readers ...

Recent Advances in iPSC Technology Volume 5

Recent Advances in iPSC Technology  Volume 5
  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2021-03-31
  • Total pages : 334
  • ISBN : 0128232692
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Summary : The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSC Technology, Volume 5 addresses the progress in induced pluripotent stem cells (iPSCs) technologies. Somatic cells can be reprogrammed into iPSCs by ...

Recent Advances in Parkinson s Disease

Recent Advances in Parkinson s Disease
  • Author : Angela Cenci-Nilsson
  • Publisher : Academic Press
  • Release Date : 2020-03
  • Total pages : 358
  • ISBN : 0128232692
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Summary : Recent Advances in Parkinson ́s Disease Research, Volume 252, represents a follow-up on two previous volumes presented in the Progress in Brain Research series, Volumes 193 and 193, both published in 2010. It contains a collection of overview articles written by leading researchers in Parkinson's, discussing the most important advances made in basic, translational ...

Recent Advances in iPSC Derived Cell Types Volume 4

Recent Advances in iPSC Derived Cell Types  Volume 4
  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2021-02-21
  • Total pages : 282
  • ISBN : 0128232692
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Summary : The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSC-derived Cell Types, Volume 4 addresses how different cell types can be derived from induced pluripotent stem cells. Somatic cells can be ...

Recent Advances in IPSC Technology Volume 5

Recent Advances in IPSC Technology  Volume 5
  • Author : Alexander Birbrair
  • Publisher : Elsevier
  • Release Date : 2021-04-27
  • Total pages : 334
  • ISBN : 0128232692
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Summary : The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSC Technology, Volume 5 addresses the progress in induced pluripotent stem cells (iPSCs) technologies. Somatic cells can be reprogrammed into iPSCs by ...

Cell Biology and Translational Medicine Volume 7

Cell Biology and Translational Medicine  Volume 7
  • Author : Kursad Turksen
  • Publisher : Springer Nature
  • Release Date : 2020-02-03
  • Total pages : 153
  • ISBN : 0128232692
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Summary : Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the ...

Lung Stem Cells in the Epithelium and Vasculature

Lung Stem Cells in the Epithelium and Vasculature
  • Author : Amy Firth,Jason X.-J. Yuan
  • Publisher : Springer
  • Release Date : 2015-05-23
  • Total pages : 345
  • ISBN : 0128232692
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Summary : This book covers the identification and role of endogenous lung stem cells in health and disease, particularly the most recent advances. In addition, it discusses the rapidly growing field of stem cells and cell therapy as it relates to lung biology and disease as well as ex vivo lung bioengineering. ...

Genome wide Approaches for Understanding Disease Mechanisms in Human IPS Derived Cells

Genome wide Approaches for Understanding Disease Mechanisms in Human IPS Derived Cells
  • Author : Valerie Sapp
  • Publisher : Unknown
  • Release Date : 2020
  • Total pages : 130
  • ISBN : 0128232692
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Summary : Human iPSCs derived cells provide the context to uncover novel mechanisms of development and disease in patient specific primary cells. The establishment of genome-scale functional genomics based approaches in iPSC derived cells complements recent advances in disease modeling in these cells and is well poised to highlight novel human specific, ...

Programmed Cells from Basic Neuroscience to Therapy

Programmed Cells from Basic Neuroscience to Therapy
  • Author : Fred H. Gage,Yves Christen
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-05-13
  • Total pages : 130
  • ISBN : 0128232692
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Summary : The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed our experimental landscape and opened new possibilities. The advances in PSC have provided an important tool for the study of human neuronal function as well as neurodegenerative and neurodevelopmental ...

Organs on chips

Organs on chips
  • Author : Yu-suke Torisawa,Yi-Chung Tung
  • Publisher : MDPI
  • Release Date : 2020-05-27
  • Total pages : 262
  • ISBN : 0128232692
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Summary : Recent advances in microsystems technology and cell culture techniques have led to the development of organ-on-chip microdevices that produce tissue-level functionality, not possible with conventional culture models, by recapitulating natural tissue architecture and microenvironmental cues within microfluidic devices. Since the physiological microenvironments in living systems are mostly microfluidic in nature, ...

Combining Induced Pluripotent Stem Cells and CRISPR Cas9 Gene Editing to Model and Characterize Rare Neurological Diseases

Combining Induced Pluripotent Stem Cells and CRISPR Cas9 Gene Editing to Model and Characterize Rare Neurological Diseases
  • Author : Scott Bell
  • Publisher : Unknown
  • Release Date : 2020
  • Total pages : 212
  • ISBN : 0128232692
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Summary : "The development of accurate and informative models is essential to the investigation of any disease. However, rare neurodevelopmental disorders have historically faced immense challenges developing effective models, as the scarcity of subjects and the invasive procedures required to obtain neural cells have limited the models available to researchers. However, recent ...

World Cancer Report 2008

World Cancer Report 2008
  • Author : International Agency for Research on Cancer
  • Publisher : International Agency for Research on Cancer
  • Release Date : 2008
  • Total pages : 510
  • ISBN : 0128232692
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Summary : "The World Cancer Report 2008" provides a comprehensive overview of cancer for all those working in the field of health-care and research, and the general reader as well. It presents information on cancer patterns, diagnosis, causes and prevention concisely, clearly outlining the growing public health crisis. Simultaneously, there is a clear ...

Pluripotent Stem Cells

Pluripotent Stem Cells
  • Author : Minoru Tomizawa
  • Publisher : BoD – Books on Demand
  • Release Date : 2016-07-20
  • Total pages : 532
  • ISBN : 0128232692
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Summary : Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this ...

Embryonic Stem Cells

Embryonic Stem Cells
  • Author : Michael S. Kallos
  • Publisher : BoD – Books on Demand
  • Release Date : 2011-10-12
  • Total pages : 520
  • ISBN : 0128232692
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Summary : The ultimate clinical implementation of embryonic stem cells will require methods and protocols to turn these unspecialized cells into the fully functioning cell types found in a wide variety of tissues and organs. In order to achieve this, it is necessary to clearly understand the signals and cues that direct ...

Connecting Sarcomere Protein Mutations to Pathogenesis in Myopathies

Connecting Sarcomere Protein Mutations to Pathogenesis in Myopathies
  • Author : Jose Renato Pinto,P. Bryant Chase
  • Publisher : Frontiers Media SA
  • Release Date : 2020-08-06
  • Total pages : 212
  • ISBN : 0128232692
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Summary : Read online Connecting Sarcomere Protein Mutations to Pathogenesis in Myopathies written by Jose Renato Pinto,P. Bryant Chase, published by Frontiers Media SA which was released on 2020-08-06. Download full Connecting Sarcomere Protein Mutations to Pathogenesis in Myopathies Books now! Available in PDF, ePub and Kindle....