Quantitative Systems Pharmacology

Written By Davide Manca
Quantitative Systems Pharmacology
  • Publsiher : Elsevier
  • Release : 18 July 2018
  • ISBN : 0444639675
  • Pages : 418 pages
  • Rating : /5 from reviews
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Download or read book entitled Quantitative Systems Pharmacology by author: Davide Manca which was release on 18 July 2018 and published by Elsevier with total page 418 pages . This book available in PDF, EPUB and Kindle Format. Quantitative Systems Pharmacology: Models and Model-Based Systems with Applications, Volume 42, provides a quantitative approach to problem-solving that is targeted to engineers. The book gathers the contributions of doctors, pharmacists, biologists, and chemists who give key information on the elements needed to model a complex machine like the human body. It presents information on diagnoses, administration and release of therapeutics, distribution metabolism and excretion of drugs, compartmental pharmacokinetics, physiologically-based pharmacokinetics, pharmacodynamics, identifiability of models, numerical methods for models identification, design of experiments, in vitro and in vivo models, and more. As the pharma community is progressively acknowledging that a quantitative and systematic approach to drug administration, release, pharmacokinetics and pharmacodynamics is highly recommended to understand the mechanisms and effects of drugs, this book is a timely resource. Outlines a model-based approach (based on Process Systems Engineering-OSE and Computer Aided Process Engineering-CAPE) in quantitative pharmacology Explains how therapeutics work in the human body and how anatomy and physiology influences drug efficacy Discusses how drugs are driven to specific targets using nanoparticles Offers insight into how in vitro and in vivo experiments help understand the drug mechanism of action and optimize their performance Includes case studies showing the positive outcome of these methods in personalized therapies, therapeutic drug monitoring, clinical trials analysis and drug formulation

Quantitative Systems Pharmacology

Quantitative Systems Pharmacology
  • Author : Davide Manca
  • Publisher : Elsevier
  • Release Date : 2018-07-18
  • Total pages : 418
  • ISBN : 0444639675
GET BOOK

Summary : Quantitative Systems Pharmacology: Models and Model-Based Systems with Applications, Volume 42, provides a quantitative approach to problem-solving that is targeted to engineers. The book gathers the contributions of doctors, pharmacists, biologists, and chemists who give key information on the elements needed to model a complex machine like the human body. It ...

The Emerging Discipline of Quantitative Systems Pharmacology

The Emerging Discipline of Quantitative Systems Pharmacology
  • Author : Tarek A. Leil,Sergey Ermakov
  • Publisher : Unknown
  • Release Date : 2015-09-07
  • Total pages : 212
  • ISBN : 0444639675
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Summary : In 2011, the National Institutes of Health (NIH), in collaboration with leaders from the pharmaceutical industry and the academic community, published a white paper describing the emerging discipline of Quantitative Systems Pharmacology (QSP), and recommended the establishment of NIH-supported interdisciplinary research and training programs for QSP. QSP is still in its ...

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune Mediated Inflammatory Diseases

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune Mediated Inflammatory Diseases
  • Author : Honghui Zhou,Diane R. Mould
  • Publisher : Wiley
  • Release Date : 2019-03-19
  • Total pages : 496
  • ISBN : 0444639675
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Summary : Thorough Overview Identifies and Addresses Critical Gaps in the Treatment of Several Chronic Diseases With increasing numbers of patients suffering from Immune-Mediated Inflammatory Diseases (IMIDs), and with the increasing reliance on biopharmaceuticals to treat them, it is imperative that researchers and medical practitioners have a thorough understanding of the absorption, ...

Systems Pharmacology and Pharmacodynamics

Systems Pharmacology and Pharmacodynamics
  • Author : Donald E. Mager,Holly H.C. Kimko
  • Publisher : Springer
  • Release Date : 2016-11-29
  • Total pages : 511
  • ISBN : 0444639675
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Summary : While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface between these two methods. This book is the first to cover the expertise from ...

Animal Biotechnology

Animal Biotechnology
  • Author : Ashish S. Verma,Anchal Singh
  • Publisher : Academic Press
  • Release Date : 2020-07-03
  • Total pages : 798
  • ISBN : 0444639675
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Summary : Animal Biotechnology: Models in Discovery and Translation, Second Edition, provides a helpful guide to anyone seeking a thorough review of animal biotechnology and its application to human disease and welfare. This updated edition covers vital fundamentals, including animal cell cultures, genome sequencing analysis, epigenetics and animal models, gene expression, and ...

Computational Systems Pharmacology and Toxicology

Computational Systems Pharmacology and Toxicology
  • Author : Rudy J Richardson,Dale E Johnson
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-03-01
  • Total pages : 332
  • ISBN : 0444639675
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Summary : The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental design, enable more rapid drug efficacy and safety testing and also reduce ...

Approaching Complex Diseases

Approaching Complex Diseases
  • Author : Mariano Bizzarri
  • Publisher : Springer Nature
  • Release Date : 2020-04-17
  • Total pages : 483
  • ISBN : 0444639675
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Summary : This volume – for pharmacologists, systems biologists, philosophers and historians of medicine – points to investigate new avenues in pharmacology research, by providing a full assessment of the premises underlying a radical shift in the pharmacology paradigm. The pharmaceutical industry is currently facing unparalleled challenges in developing innovative drugs. While drug-developing scientists ...

Preclinical QSP Modeling in the Pharmaceutical Industry An IQ Consortium Survey Examining the Current Landscape

Preclinical QSP Modeling in the Pharmaceutical Industry  An IQ Consortium Survey Examining the Current Landscape
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 0444639675
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Summary : Abstract : A cross‐industry survey was conducted to assess the landscape of preclinical quantitative systems pharmacology (QSP) modeling within pharmaceutical companies. This article presents the survey results, which provide insights on the current state of preclinical QSP modeling in addition to future opportunities. Our results call attention to the need ...

Applied Pharmacometrics

Applied Pharmacometrics
  • Author : Stephan Schmidt,Hartmut Derendorf
  • Publisher : Springer
  • Release Date : 2014-12-01
  • Total pages : 565
  • ISBN : 0444639675
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Summary : This comprehensive volume provides an update on the current state of pharmacometrics in drug development. It consists of nineteen chapters all written by leading scientists from the pharmaceutical industry, regulatory agencies and academia. After an introduction of the basic pharmacokinetic and pharmacodynamic concepts of pharmacometrics in drug development, the book ...

Proceedings of the First International Pharmacological Meeting Abstracts

Proceedings of the First International Pharmacological Meeting  Abstracts
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1962
  • Total pages : 212
  • ISBN : 0444639675
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Summary : Read online Proceedings of the First International Pharmacological Meeting Abstracts written by , published by which was released on 1962. Download full Proceedings of the First International Pharmacological Meeting Abstracts Books now! Available in PDF, ePub and Kindle....

Artificial Intelligence for Translational Pharmacology

Artificial Intelligence for Translational Pharmacology
  • Author : Zhi-Liang Ji,Lixia Yao,Kartick Chandra Pramanik,Zhaohui John Cai
  • Publisher : Frontiers Media SA
  • Release Date : 2020-07-28
  • Total pages : 212
  • ISBN : 0444639675
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Summary : Read online Artificial Intelligence for Translational Pharmacology written by Zhi-Liang Ji,Lixia Yao,Kartick Chandra Pramanik,Zhaohui John Cai, published by Frontiers Media SA which was released on 2020-07-28. Download full Artificial Intelligence for Translational Pharmacology Books now! Available in PDF, ePub and Kindle....

Quantitative Methods in Human Pharmacology and Therapeutics

Quantitative Methods in Human Pharmacology and Therapeutics
  • Author : Desmond Roger Laurence
  • Publisher : Unknown
  • Release Date : 1959
  • Total pages : 253
  • ISBN : 0444639675
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Summary : Read online Quantitative Methods in Human Pharmacology and Therapeutics written by Desmond Roger Laurence, published by which was released on 1959. Download full Quantitative Methods in Human Pharmacology and Therapeutics Books now! Available in PDF, ePub and Kindle....

Bibliographia Primatologica Anatomy embryology quantitative morphology physiology pharmacology psychobiology primate phylogeny miscellanea

Bibliographia Primatologica  Anatomy  embryology   quantitative morphology  physiology  pharmacology   psychobiology  primate phylogeny   miscellanea
  • Author : Theodore Cedric Ruch
  • Publisher : Unknown
  • Release Date : 1941
  • Total pages : 212
  • ISBN : 0444639675
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Summary : Read online Bibliographia Primatologica Anatomy embryology quantitative morphology physiology pharmacology psychobiology primate phylogeny miscellanea written by Theodore Cedric Ruch, published by which was released on 1941. Download full Bibliographia Primatologica Anatomy embryology quantitative morphology physiology pharmacology psychobiology primate phylogeny miscellanea Books now! Available in PDF, ePub and Kindle....

Portonovo Conferences I on Endocrine Pharmacology Compartmental Models and Control Systems September 2 7 1974 II on Biomathematics September 27 28 1978

Portonovo Conferences  I  on Endocrine Pharmacology  Compartmental Models and Control Systems  September 2 7  1974  II  on Biomathematics  September 27 28  1978
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1979
  • Total pages : 319
  • ISBN : 0444639675
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Summary : Read online Portonovo Conferences I on Endocrine Pharmacology Compartmental Models and Control Systems September 2 7 1974 II on Biomathematics September 27 28 1978 written by , published by which was released on 1979. Download full Portonovo Conferences I on Endocrine Pharmacology Compartmental Models and Control Systems September 2 7 1974 II on Biomathematics September 27 28 1978 Books now! Available in PDF, ePub ...

Pharmacology of the Endocrine System and Related Drugs

Pharmacology of the Endocrine System and Related Drugs
  • Author : Lars Philip Bengtsson,M. Tausk,Daniele Bovet
  • Publisher : Pergamon
  • Release Date : 1971
  • Total pages : 519
  • ISBN : 0444639675
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Summary : Read online Pharmacology of the Endocrine System and Related Drugs written by Lars Philip Bengtsson,M. Tausk,Daniele Bovet, published by Pergamon which was released on 1971. Download full Pharmacology of the Endocrine System and Related Drugs Books now! Available in PDF, ePub and Kindle....