Quantitative Systems Pharmacology

Written By Davide Manca
Quantitative Systems Pharmacology
  • Publsiher : Elsevier
  • Release : 18 July 2018
  • ISBN : 0444639675
  • Pages : 418 pages
  • Rating : /5 from reviews
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Download or read book entitled Quantitative Systems Pharmacology by author: Davide Manca which was release on 18 July 2018 and published by Elsevier with total page 418 pages . This book available in PDF, EPUB and Kindle Format. Quantitative Systems Pharmacology: Models and Model-Based Systems with Applications, Volume 42, provides a quantitative approach to problem-solving that is targeted to engineers. The book gathers the contributions of doctors, pharmacists, biologists, and chemists who give key information on the elements needed to model a complex machine like the human body. It presents information on diagnoses, administration and release of therapeutics, distribution metabolism and excretion of drugs, compartmental pharmacokinetics, physiologically-based pharmacokinetics, pharmacodynamics, identifiability of models, numerical methods for models identification, design of experiments, in vitro and in vivo models, and more. As the pharma community is progressively acknowledging that a quantitative and systematic approach to drug administration, release, pharmacokinetics and pharmacodynamics is highly recommended to understand the mechanisms and effects of drugs, this book is a timely resource. Outlines a model-based approach (based on Process Systems Engineering-OSE and Computer Aided Process Engineering-CAPE) in quantitative pharmacology Explains how therapeutics work in the human body and how anatomy and physiology influences drug efficacy Discusses how drugs are driven to specific targets using nanoparticles Offers insight into how in vitro and in vivo experiments help understand the drug mechanism of action and optimize their performance Includes case studies showing the positive outcome of these methods in personalized therapies, therapeutic drug monitoring, clinical trials analysis and drug formulation

Quantitative Systems Pharmacology

Quantitative Systems Pharmacology
  • Author : Davide Manca
  • Publisher : Elsevier
  • Release Date : 2018-07-18
  • Total pages : 418
  • ISBN : 0444639675
GET BOOK

Summary : Quantitative Systems Pharmacology: Models and Model-Based Systems with Applications, Volume 42, provides a quantitative approach to problem-solving that is targeted to engineers. The book gathers the contributions of doctors, pharmacists, biologists, and chemists who give key information on the elements needed to model a complex machine like the human body. It ...

The Emerging Discipline of Quantitative Systems Pharmacology

The Emerging Discipline of Quantitative Systems Pharmacology
  • Author : Tarek A. Leil,Sergey Ermakov
  • Publisher : Unknown
  • Release Date : 2015-09-07
  • Total pages : 212
  • ISBN : 0444639675
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Summary : In 2011, the National Institutes of Health (NIH), in collaboration with leaders from the pharmaceutical industry and the academic community, published a white paper describing the emerging discipline of Quantitative Systems Pharmacology (QSP), and recommended the establishment of NIH-supported interdisciplinary research and training programs for QSP. QSP is still in its ...

Quantitative Systems Pharmacology Modeling of Biotherapeutics in Oncology

Quantitative Systems Pharmacology Modeling of Biotherapeutics in Oncology
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2021
  • Total pages : 218
  • ISBN : 0444639675
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Summary : Read online Quantitative Systems Pharmacology Modeling of Biotherapeutics in Oncology written by , published by which was released on 2021. Download full Quantitative Systems Pharmacology Modeling of Biotherapeutics in Oncology Books now! Available in PDF, ePub and Kindle....

The Emerging Discipline of Quantitative Systems Pharmacology

The Emerging Discipline of Quantitative Systems Pharmacology
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2021-07-26
  • Total pages : 212
  • ISBN : 0444639675
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Summary : Read online The Emerging Discipline of Quantitative Systems Pharmacology written by , published by which was released on . Download full The Emerging Discipline of Quantitative Systems Pharmacology Books now! Available in PDF, ePub and Kindle....

Biochemical Thermodynamic Modelling of Cellular Bioenergetics

Biochemical Thermodynamic Modelling of Cellular Bioenergetics
  • Author : R. A. Kelly
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 0444639675
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Summary : Read online Biochemical Thermodynamic Modelling of Cellular Bioenergetics written by R. A. Kelly, published by which was released on 2018. Download full Biochemical Thermodynamic Modelling of Cellular Bioenergetics Books now! Available in PDF, ePub and Kindle....

Abstracts ASCPT 2015 Annual Meeting Quantitative Systems Pharmacology Multiscale Model Based Drug Development Through Integrating Systems Biology and Pharmacometrics Pre Conference

Abstracts ASCPT 2015 Annual Meeting   Quantitative Systems Pharmacology  Multiscale Model Based Drug Development Through Integrating Systems Biology and Pharmacometrics Pre Conference
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2015
  • Total pages : 116
  • ISBN : 0444639675
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Summary : Read online Abstracts ASCPT 2015 Annual Meeting Quantitative Systems Pharmacology Multiscale Model Based Drug Development Through Integrating Systems Biology and Pharmacometrics Pre Conference written by , published by which was released on 2015. Download full Abstracts ASCPT 2015 Annual Meeting Quantitative Systems Pharmacology Multiscale Model Based Drug Development Through Integrating Systems Biology and Pharmacometrics ...

Abstracts ASCPT 2013 Annual Meeting Quantitative Systems Pharmacology an Integrating Framework for Translational Medicine

Abstracts ASCPT 2013 Annual Meeting   Quantitative Systems Pharmacology  an Integrating Framework for Translational Medicine
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2013
  • Total pages : 137
  • ISBN : 0444639675
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Summary : Read online Abstracts ASCPT 2013 Annual Meeting Quantitative Systems Pharmacology an Integrating Framework for Translational Medicine written by , published by which was released on 2013. Download full Abstracts ASCPT 2013 Annual Meeting Quantitative Systems Pharmacology an Integrating Framework for Translational Medicine Books now! Available in PDF, ePub and Kindle....

Systems Pharmacology and Pharmacodynamics

Systems Pharmacology and Pharmacodynamics
  • Author : Donald E. Mager,Holly H.C. Kimko
  • Publisher : Springer
  • Release Date : 2016-11-29
  • Total pages : 511
  • ISBN : 0444639675
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Summary : While systems biology and pharmacodynamics have evolved in parallel, there are significant interrelationships that can enhance drug discovery and enable optimized therapy for each patient. Systems pharmacology is the relatively new discipline that is the interface between these two methods. This book is the first to cover the expertise from ...

Computational Systems Pharmacology and Toxicology

Computational Systems Pharmacology and Toxicology
  • Author : Rudy J Richardson,Dale E Johnson
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-03-01
  • Total pages : 332
  • ISBN : 0444639675
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Summary : The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental design, enable more rapid drug efficacy and safety testing and also reduce ...

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune Mediated Inflammatory Diseases

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune Mediated Inflammatory Diseases
  • Author : Honghui Zhou,Diane R. Mould
  • Publisher : Wiley
  • Release Date : 2019-03-19
  • Total pages : 496
  • ISBN : 0444639675
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Summary : Thorough Overview Identifies and Addresses Critical Gaps in the Treatment of Several Chronic Diseases With increasing numbers of patients suffering from Immune-Mediated Inflammatory Diseases (IMIDs), and with the increasing reliance on biopharmaceuticals to treat them, it is imperative that researchers and medical practitioners have a thorough understanding of the absorption, ...

Computational Systems Pharmacology and Toxicology

Computational Systems Pharmacology and Toxicology
  • Author : Rudy J Richardson,Dale E Johnson
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-03-01
  • Total pages : 332
  • ISBN : 0444639675
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Summary : The network approaches of systems pharmacology and toxicology serve as early predictors of the most relevant screening approach to pursue both in drug discovery and development and ecotoxicological assessments. Computational approaches have the potential to improve toxicological experimental design, enable more rapid drug efficacy and safety testing and also reduce ...

Translational Systems Medicine and Oral Disease

Translational Systems Medicine and Oral Disease
  • Author : Stephen Sonis,Alessandro Villa
  • Publisher : Academic Press
  • Release Date : 2019-09-14
  • Total pages : 458
  • ISBN : 0444639675
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Summary : Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral ...

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune Mediated Inflammatory Diseases

Quantitative Pharmacology and Individualized Therapy Strategies in Development of Therapeutic Proteins for Immune Mediated Inflammatory Diseases
  • Author : Honghui Zhou,Diane R. Mould
  • Publisher : John Wiley & Sons
  • Release Date : 2019-02-18
  • Total pages : 496
  • ISBN : 0444639675
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Summary : Thorough Overview Identifies and Addresses Critical Gaps in the Treatment of Several Chronic Diseases With increasing numbers of patients suffering from Immune-Mediated Inflammatory Diseases (IMIDs), and with the increasing reliance on biopharmaceuticals to treat them, it is imperative that researchers and medical practitioners have a thorough understanding of the absorption, ...

Medical Empathy Pharmacological Systems and Treatment Strategies in Integrative Cardiovascular Chinese Medicine

Medical Empathy  Pharmacological Systems  and Treatment Strategies in Integrative Cardiovascular Chinese Medicine
  • Author : Anika Niambi Al-Shura
  • Publisher : Academic Press
  • Release Date : 2019-10-18
  • Total pages : 196
  • ISBN : 0444639675
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Summary : Medical Empathy, Pharmacological Systems, and Treatment Strategies in Integrative Cardiovascular Chinese Medicine, volume two in the Integrative Cardiovascular Chinese Medicine series, presents sections on holism and humanity in medicine, considering the patient, medical empathy in prescribing, modifying and weaning, an overview of pharmacologic systems, an overview of pharmacology sciences and ...

An Introduction to Computational Systems Biology

An Introduction to Computational Systems Biology
  • Author : Karthik Raman
  • Publisher : CRC Press
  • Release Date : 2021-05-30
  • Total pages : 358
  • ISBN : 0444639675
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Summary : This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks—a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less ...