Protein Homeostasis Diseases

Written By Angel L. Pey
Protein Homeostasis Diseases
  • Publsiher : Academic Press
  • Release : 13 February 2020
  • ISBN : 0128191333
  • Pages : 450 pages
  • Rating : /5 from reviews
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Download or read book entitled Protein Homeostasis Diseases by author: Angel L. Pey which was release on 13 February 2020 and published by Academic Press with total page 450 pages . This book available in PDF, EPUB and Kindle Format. Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein homeostasis disease, including the use of natural and pharmacological small molecules to treat common and rare protein homeostasis disorders. Contributions from international experts discuss the biochemical and genetic components of protein homeostasis disorders, the mechanisms by which genetic variants may cause loss-of-function and gain-of-toxic-function, and how natural ligands can restore protein function and homeostasis in genetic diseases. Applied chapters provide guidance on employing high throughput sequencing and screening methodologies to develop pharmacological chaperones and repurpose approved drugs to treat protein homeostasis disorders. Provides an interdisciplinary examination of protein homeostasis disorders, with an emphasis on treatment strategies employing small natural and pharmacological ligands Offers applied approaches in employing high throughput sequencing and screening to develop pharmacological chaperones to treat protein homeostasis disease Gathers expertise from a range of international chapter authors who work across various biological methods and disease specific disciplines of relevance

Protein Homeostasis Diseases

Protein Homeostasis Diseases
  • Author : Angel L. Pey
  • Publisher : Academic Press
  • Release Date : 2020-02-13
  • Total pages : 450
  • ISBN : 0128191333
GET BOOK

Summary : Protein Homeostasis Diseases: Mechanisms and Novel Therapies offers an interdisciplinary examination of the fundamental aspects, biochemistry and molecular biology of protein homeostasis disease, including the use of natural and pharmacological small molecules to treat common and rare protein homeostasis disorders. Contributions from international experts discuss the biochemical and genetic components ...

Protein Homeostasis

Protein Homeostasis
  • Author : Richard I. Morimoto,Dennis J. Selkoe,Jeffery W. Kelly
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 349
  • ISBN : 0128191333
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Summary : Proper expression, folding, transport, and clearance of proteins is critical for cell function. Chaperones and enzymes that posttranslationally assist newly synthesized proteins help ensure that they fold correctly or are degraded. Translocation machineries, proteasomes, and autophagic activities help to localize and degrade proteins as necessary. Stress and aging can cause ...

Proteostasis and Disease

Proteostasis and Disease
  • Author : Rosa Barrio,James D. Sutherland,Manuel S. Rodriguez
  • Publisher : Springer Nature
  • Release Date : 2020-04-09
  • Total pages : 348
  • ISBN : 0128191333
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Summary : This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and disease. With new discoveries contributing to the increasing complexity of this topic, the book offers a detailed overview of the pathways regulating protein homeostasis, including autophagy and ...

Protein Quality Control in Neurodegenerative Diseases

Protein Quality Control in Neurodegenerative Diseases
  • Author : Richard I. Morimoto,Yves Christen
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-13
  • Total pages : 136
  • ISBN : 0128191333
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Summary : The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of ...

Research Grants Index

Research Grants Index
  • Author : National Institutes of Health (U.S.). Division of Research Grants
  • Publisher : Unknown
  • Release Date : 1966
  • Total pages : 212
  • ISBN : 0128191333
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Summary : Read online Research Grants Index written by National Institutes of Health (U.S.). Division of Research Grants, published by which was released on 1966. Download full Research Grants Index Books now! Available in PDF, ePub and Kindle....

Biomedical Index to PHS supported Research

Biomedical Index to PHS supported Research
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1991
  • Total pages : 212
  • ISBN : 0128191333
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Summary : Read online Biomedical Index to PHS supported Research written by , published by which was released on 1991. Download full Biomedical Index to PHS supported Research Books now! Available in PDF, ePub and Kindle....

Research Awards Index

Research Awards Index
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1984
  • Total pages : 212
  • ISBN : 0128191333
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Summary : Read online Research Awards Index written by , published by which was released on 1984. Download full Research Awards Index Books now! Available in PDF, ePub and Kindle....

The Journals of Gerontology

The Journals of Gerontology
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 212
  • ISBN : 0128191333
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Summary : Read online The Journals of Gerontology written by , published by which was released on 2009. Download full The Journals of Gerontology Books now! Available in PDF, ePub and Kindle....

Annual Review of Genomics and Human Genetics

Annual Review of Genomics and Human Genetics
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 212
  • ISBN : 0128191333
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Summary : Read online Annual Review of Genomics and Human Genetics written by , published by which was released on 2009. Download full Annual Review of Genomics and Human Genetics Books now! Available in PDF, ePub and Kindle....

Protein Folding Disorders Of The Central Nervous System

Protein Folding Disorders Of The Central Nervous System
  • Author : Ghiso Jorge A,Rostagno Agueda A
  • Publisher : World Scientific
  • Release Date : 2017-09-15
  • Total pages : 336
  • ISBN : 0128191333
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Summary : This exciting new book explores the dark side of the molecular protein assembly bringing an updated view of how failures in the homeostatic mechanisms that efficiently regulate protein folding leads to the accumulation of structurally abnormal pathogenic assemblies, encompassing an emerging group of diseases collectively known as "Protein Folding Disorders." ...

Wiley Encyclopedia of Molecular Medicine Volume 3

Wiley Encyclopedia of Molecular Medicine  Volume 3
  • Author : Wiley
  • Publisher : Wiley-Interscience
  • Release Date : 2001-11-01
  • Total pages : 3699
  • ISBN : 0128191333
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Summary : Read online Wiley Encyclopedia of Molecular Medicine Volume 3 written by Wiley, published by Wiley-Interscience which was released on 2001-11-01. Download full Wiley Encyclopedia of Molecular Medicine Volume 3 Books now! Available in PDF, ePub and Kindle....

Proteinuria

Proteinuria
  • Author : Amadeo J. Pesce,Martin Roy First
  • Publisher : Marcel Dekker Incorporated
  • Release Date : 1979
  • Total pages : 294
  • ISBN : 0128191333
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Summary : Read online Proteinuria written by Amadeo J. Pesce,Martin Roy First, published by Marcel Dekker Incorporated which was released on 1979. Download full Proteinuria Books now! Available in PDF, ePub and Kindle....

Soft Nanotechnology

Soft Nanotechnology
  • Author : Anonim
  • Publisher : Faraday Discussions
  • Release Date : 2009
  • Total pages : 394
  • ISBN : 0128191333
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Summary : This book will incorporate aspects of structuring soft-materials at the nanoscale and the incorporation of such materials into actual devices. Soft nanotechnology aims to build on our knowledge of biological systems, by implementing self-assembly and 'wet chemistry' into electronic devices, actuators, fluidics, etc. Understanding, predicting and utilising the rules of ...

Nurse s Manual of Laboratory and Diagnostic Tests

Nurse s Manual of Laboratory and Diagnostic Tests
  • Author : Bonita Morrow Cavanaugh
  • Publisher : F. A. Davis Company
  • Release Date : 1999
  • Total pages : 1033
  • ISBN : 0128191333
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Summary : This manual contains comprehensive information on laboratory and diagnostic tests in a quick-retrieval format with a strong focus on nursing care before, during, and after each test....

Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2006
  • Total pages : 212
  • ISBN : 0128191333
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Summary : Read online Proceedings of the National Academy of Sciences of the United States of America written by , published by which was released on 2006. Download full Proceedings of the National Academy of Sciences of the United States of America Books now! Available in PDF, ePub and Kindle....