Piperidine Based Drug Discovery

Written By Ruben Vardanyan
Piperidine Based Drug Discovery
  • Publsiher : Elsevier
  • Release : 12 June 2017
  • ISBN : 0128134283
  • Pages : 358 pages
  • Rating : /5 from reviews
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Download or read book entitled Piperidine Based Drug Discovery by author: Ruben Vardanyan which was release on 12 June 2017 and published by Elsevier with total page 358 pages . This book available in PDF, EPUB and Kindle Format. Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related areas, it is hoped that this volume will encourage and inspire the continued design and development of novel pharmaceuticals based on Piperidine and its derivatives. Heterocyclic compounds are of central importance to medicinal chemistry, as demonstrated by the high percentage of marketable drugs that feature heterocyclic fragments in their structures. As starting points for drug discovery they offer a broad range of attractive properties, and a detailed understanding of the particular characteristics of each is of great benefit to researchers. The most commonly used heterocycle among US FDA approved pharmaceuticals, Piperidine is an extremely important building block in the synthesis of medicinal agents. This heterocycle and its derivatives exhibit a number of important functionalities and have been employed variously as CNS modulators, antiaggregants, anticoagulants, antihistamines, anti-cancer drugs and analgesics. Explores this extremely important heterocycle to a high level of detail Describes synthesis methods for 70 current drugs based on Piperidine scaffolds Gives drug designers all the key knowledge required to develop new drugs utilizing Piperidine Provides pharmacologists a solid overview of the chemical background of existing Piperidine-based drugs

Piperidine Based Drug Discovery

Piperidine Based Drug Discovery
  • Author : Ruben Vardanyan
  • Publisher : Elsevier
  • Release Date : 2017-06-12
  • Total pages : 358
  • ISBN : 0128134283
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Summary : Piperidine-Based Drug Discovery outlines the complexities of Piperidine scaffold use in drug discovery, including derivative chemistry, structural properties, methods of synthesis and practical implementations. Piperidine scaffolds are the cornerstones of over 70 commercialized drugs (including multiple blockbusters). Designed as a guide for both experts and students working in this and related ...

Fragment based Drug Discovery

Fragment based Drug Discovery
  • Author : Daniel A. Erlanson,Wolfgang Jahnke,Raimund Mannhold,Hugo Kubinyi,Gerd Folkers
  • Publisher : John Wiley & Sons
  • Release Date : 2016-02-23
  • Total pages : 528
  • ISBN : 0128134283
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Summary : From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often yielding results where other methods have failed. Written by the pioneers in the field, this book provides a comprehensive overview of current methods and applications of ...

Green Sustainable Process for Chemical and Environmental Engineering and Science

Green Sustainable Process for Chemical and Environmental Engineering and Science
  • Author : Dr. Inamuddin,Rajender Boddula,Mohd Imran Ahamed,Abdullah M. Asiri
  • Publisher : Elsevier
  • Release Date : 2020-12-01
  • Total pages : 374
  • ISBN : 0128134283
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Summary : Green Sustainable Process for Chemical and Environmental Engineering and Science: Solvents for the Pharmaceutical Industry aims at providing a detailed overview of applications of green solvents in pharmaceutical industries. It also focuses on providing a detailed literature survey on the green solvents for pharmaceutical analysis, drug design, synthesis, and production, ...

Carbohydrate based Drug Discovery 2 Volume Set

Carbohydrate based Drug Discovery  2 Volume Set
  • Author : Chi-Huey Wong
  • Publisher : Wiley-VCH
  • Release Date : 2003-10-17
  • Total pages : 947
  • ISBN : 0128134283
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Summary : To exploit the full potential of this diverse compound class for the development of novel active substances, this handbook presents the latest knowledge on carbohydrate chemistry and biochemistry. While it is unique in covering the entire field, particular emphasis is placed on carbohydrates with pharmaceutical potential. Topics include the following: > ...

Medicinal Chemistry and Drug Discovery Nervous system agents

Medicinal Chemistry and Drug Discovery  Nervous system agents
  • Author : Alfred Burger
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 212
  • ISBN : 0128134283
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Summary : Read online Medicinal Chemistry and Drug Discovery Nervous system agents written by Alfred Burger, published by which was released on 2003. Download full Medicinal Chemistry and Drug Discovery Nervous system agents Books now! Available in PDF, ePub and Kindle....

Burger s Medicinal Chemistry and Drug Discovery Therapeutic Agents

Burger s Medicinal Chemistry and Drug Discovery  Therapeutic Agents
  • Author : Manfred E. Wolff
  • Publisher : Wiley-Interscience
  • Release Date : 1996-04-26
  • Total pages : 680
  • ISBN : 0128134283
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Summary : The most comprehensive source of the latest information in drug discovery and medicinal chemistry BURGER'S MEDICINAL CHEMISTRY AND DRUG DISCOVERY, FIFTH EDITION, Volume 2: Therapeutic Agents Renowned for its incisive, systematic examination of the new classes of drugs, Burger's Medicinal Chemistry and Drug Discovery provides professionals with thorough, yet selective access ...

Directory of Graduate Research

Directory of Graduate Research
  • Author : American Chemical Society. Committee on Professional Training
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 212
  • ISBN : 0128134283
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Summary : Faculties, publications and doctoral theses in departments or divisions of chemistry, chemical engineering, biochemistry and pharmaceutical and/or medicinal chemistry at universities in the United States and Canada....

Methods and Techniques in Drug Discovery

Methods and Techniques in Drug Discovery
  • Author : John Sterling,Ellyn J. T. D. Kerr,Shannon Simons
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 266
  • ISBN : 0128134283
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Summary : Read online Methods and Techniques in Drug Discovery written by John Sterling,Ellyn J. T. D. Kerr,Shannon Simons, published by which was released on 2005. Download full Methods and Techniques in Drug Discovery Books now! Available in PDF, ePub and Kindle....

Structure Function Analysis of G Protein Coupled Receptors

Structure Function Analysis of G Protein Coupled Receptors
  • Author : J├╝rgen Wess
  • Publisher : Wiley-Liss
  • Release Date : 1999-06-15
  • Total pages : 432
  • ISBN : 0128134283
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Summary : G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions. GPCRs or GPCR-dependent signalling pathways are the targets of a very large number of therapeutically useful drugs. Detailed knowledge about the molecular structure ...

Applications of Combinatorial Synthesis to Drug Discovery and Catalysis Development

Applications of Combinatorial Synthesis to Drug Discovery and Catalysis Development
  • Author : Barry A. Bunin
  • Publisher : Unknown
  • Release Date : 1996
  • Total pages : 342
  • ISBN : 0128134283
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Summary : Read online Applications of Combinatorial Synthesis to Drug Discovery and Catalysis Development written by Barry A. Bunin, published by which was released on 1996. Download full Applications of Combinatorial Synthesis to Drug Discovery and Catalysis Development Books now! Available in PDF, ePub and Kindle....

Privileged Structures in Drug Discovery

Privileged Structures in Drug Discovery
  • Author : Larry Yet
  • Publisher : John Wiley & Sons
  • Release Date : 2018-03-27
  • Total pages : 560
  • ISBN : 0128134283
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Summary : A comprehensive guide to privileged structures and their application in the discovery of new drugs The use of privileged structures is a viable strategy in the discovery of new medicines at the lead optimization stages of the drug discovery process. Privileged Structures in Drug Discovery offers a comprehensive text that ...

Burger s Medicinal Chemistry and Drug Discovery Drug Discovery

Burger s Medicinal Chemistry and Drug Discovery  Drug Discovery
  • Author : Donald J. Abraham
  • Publisher : Wiley-Interscience
  • Release Date : 2003
  • Total pages : 968
  • ISBN : 0128134283
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Summary : This is Volume 1: Drug Discovery, of Burger's Medicinal Chemistry and Drug Discovery, 6th Edition. This new volume contains critical new chapters on Virtual Screening, Bioinformatics and Chemical Information Computing Systems in Drug Discovery. To purchase the entire 6 volume set, please refer to ISBN 0-471-37032-0. For a complete list ...

Small molecule scaffold synthesis one bead one compound library synthesis and method development in drug discovery

Small molecule scaffold synthesis  one bead one compound library synthesis  and method development in drug discovery
  • Author : Seth M. Dixon
  • Publisher : Unknown
  • Release Date : 2006
  • Total pages : 630
  • ISBN : 0128134283
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Summary : Read online Small molecule scaffold synthesis one bead one compound library synthesis and method development in drug discovery written by Seth M. Dixon, published by which was released on 2006. Download full Small molecule scaffold synthesis one bead one compound library synthesis and method development in drug discovery Books now! Available ...

Medicinal Chemistry and Drug Discovery Autocoids diagnostics and drugs from new biology

Medicinal Chemistry and Drug Discovery  Autocoids  diagnostics  and drugs from new biology
  • Author : Alfred Burger
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 212
  • ISBN : 0128134283
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Summary : Read online Medicinal Chemistry and Drug Discovery Autocoids diagnostics and drugs from new biology written by Alfred Burger, published by which was released on 2003. Download full Medicinal Chemistry and Drug Discovery Autocoids diagnostics and drugs from new biology Books now! Available in PDF, ePub and Kindle....

Decision Making in Drug Research

Decision Making in Drug Research
  • Author : Franz Gross
  • Publisher : Unknown
  • Release Date : 1983
  • Total pages : 244
  • ISBN : 0128134283
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Summary : Read online Decision Making in Drug Research written by Franz Gross, published by which was released on 1983. Download full Decision Making in Drug Research Books now! Available in PDF, ePub and Kindle....