Phytochemicals as Lead Compounds for New Drug Discovery

Written By Chukwuebuka Egbuna
Phytochemicals as Lead Compounds for New Drug Discovery
  • Publsiher : Elsevier
  • Release : 07 September 2019
  • ISBN : 0128178914
  • Pages : 378 pages
  • Rating : /5 from reviews
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Download or read book entitled Phytochemicals as Lead Compounds for New Drug Discovery by author: Chukwuebuka Egbuna which was release on 07 September 2019 and published by Elsevier with total page 378 pages . This book available in PDF, EPUB and Kindle Format. Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs and have played a major role in the treatment of diseases around the world. These compounds possess enormous structural and chemical diversity and have led to many important discoveries. This book presents fundament concepts and factors affecting the choice for plant-based products, as well as recent advances in computer-aided drug discovery and FDA drug candidacy acceptance criteria. It also details the various bioactive lead compounds and molecular targets for a range of life-threatening diseases including cancer, diabetes, and neurodegenerative diseases. Written by a global team of experts, Phytochemicals as Lead Compounds for New Drug Discovery is an ideal resource for drug developers, phytochemists, plant biochemists, food and medicinal chemists, nutritionists and toxicologists, chemical ecologists, taxonomists, analytical chemists, and other researchers in those fields. It will also be very valuable to professors, students, and researchers in this domain. Presents fundamental concepts and factors affecting choice for plant-based products Details the FDA drug candidacy acceptance criteria, including bottlenecks and way forward Highlights recent advances in computational-based drug discovery Focuses on the discovery of new drugs and potential druggable targets for the treatment of chronic diseases of world importance

Phytochemicals as Lead Compounds for New Drug Discovery

Phytochemicals as Lead Compounds for New Drug Discovery
  • Author : Chukwuebuka Egbuna,Shashank Kumar,Jonathan C. Ifemeje,Shahira M. Ezzat,Saravanan Kaliyaperumal
  • Publisher : Elsevier
  • Release Date : 2019-09-07
  • Total pages : 378
  • ISBN : 0128178914
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Summary : Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage of the recent advances in the discovery of phytochemicals from medicinal plants as models to the development of new drugs and chemical entities. Functional bioactive compounds of plant origin have been an invaluable source for many human therapeutic drugs ...

Botanical Leads for Drug Discovery

Botanical Leads for Drug Discovery
  • Author : Bikarma Singh
  • Publisher : Springer Nature
  • Release Date : 2020-10-05
  • Total pages : 468
  • ISBN : 0128178914
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Summary : Active botanical ingredients are a prime requirement for herbal formulations and discovering a drug is all about integration of science disciplines. In recent decades there has been a growing interest in treating wounds and diseases using traditional remedies based on local herbs, combined with chemical advances. Although this has led ...

Bioactive Phytochemicals Drug Discovery to Product Development

Bioactive Phytochemicals  Drug Discovery to Product Development
  • Author : Javed Ahmad,Javed Ahamad
  • Publisher : Bentham Science Publishers
  • Release Date : 2020-10-28
  • Total pages : 238
  • ISBN : 0128178914
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Summary : Natural bioactive compounds from medicinal plants are inexplicably diverse in chemical structure and biological properties. The unmet therapeutic requirements for various diseases serve as a guide for researchers to study natural compounds. These studies are intended to isolate, identify the structural characterization and eventually discover the pharmacological activity of natural ...

Poisonous Plants and Phytochemicals in Drug Discovery

Poisonous Plants and Phytochemicals in Drug Discovery
  • Author : Andrew G. Mtewa,Chukwuebuka Egbuna,G. M. Narasimha Rao
  • Publisher : John Wiley & Sons
  • Release Date : 2020-12-04
  • Total pages : 432
  • ISBN : 0128178914
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Summary : Focusing on phytochemicals and their potential for drug discovery, this book offers a comprehensive resource on poisonous plants and their applications in chemistry and in pharmacology. Provides a comprehensive resource on phytotoxins, covering historical perspectives, modern applications, and their potential in drug discovery - Covers the mechanisms, benefits, risks and ...

Phytochemicals for Pest Control

Phytochemicals for Pest Control
  • Author : American Chemical Society,Paul Arthur Hedin,American Chemical Society. Division of Agrochemicals,International Chemical Congress of Pacific Basin Studies,American Chemical Society Staff
  • Publisher : Amer Chemical Society
  • Release Date : 1997
  • Total pages : 372
  • ISBN : 0128178914
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Summary : This volume identifies and describes biologically active natural products which can be used to manage a wide variety of pests, including insects, weeds, and fungi. The book presents structure-activity studies of the pest control agents and evaluates active proteins and peptides affecting insects. It also covers the identification of new ...

Phytochemicals and Phytopharmaceuticals

Phytochemicals and Phytopharmaceuticals
  • Author : Fereidoon Shahidi,Chi-Tang Ho
  • Publisher : The American Oil Chemists Society
  • Release Date : 2000
  • Total pages : 431
  • ISBN : 0128178914
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Summary : Shahidi (biochemistry, Memorial U. of Newfoundland) and Ho (food science, Rutgers U.) present a monograph from an international group of scientists that contains 37 papers discussing plant bioactives in a varied range of research areas. Specific topics include variables affecting the phytochemical contents of garlic and their health benefits, the role ...

Phytochemical analysis and cholesterol lowering efficiency of Averrhoa carambola Linn star fruit

Phytochemical analysis and cholesterol lowering efficiency of Averrhoa carambola Linn  star fruit
  • Author : Prem Jose Vazhacharickal,Jiby John Mathew,Sajeshkumar N. K.,Ratheesh Mohanan,Ellamplackill Surya Santhosh
  • Publisher : GRIN Verlag
  • Release Date : 2017-07-10
  • Total pages : 27
  • ISBN : 0128178914
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Summary : Scientific Study from the year 2017 in the subject Agrarian Studies, grade: 1.5, Mar Augusthinose College, course: Biochemistry, language: English, abstract: Aqueous extract of the fruit pulp of Averrhoa carambola (star fruit) were evaluated for cholesterol lowering effect, in vitro, against various fatty food materials. Peoples are consuming food items made out ...

Science Culture

Science   Culture
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1998
  • Total pages : 212
  • ISBN : 0128178914
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Summary : Read online Science Culture written by , published by which was released on 1998. Download full Science Culture Books now! Available in PDF, ePub and Kindle....

Phytochemical and pharmacological evaluation of different fractions of Lannea grandis Engl Family Anacardiaceae

Phytochemical and pharmacological evaluation of different fractions of Lannea grandis Engl  Family  Anacardiaceae
  • Author : Sharmin Akhter
  • Publisher : GRIN Verlag
  • Release Date : 2014-07-14
  • Total pages : 129
  • ISBN : 0128178914
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Summary : Master's Thesis from the year 2012 in the subject Pharmicology, , course: Pharmacy, language: English, abstract: The present research work was conducted to investigate the phytochemical and pharmacological activities of the different fractions of Lannea grandis Engl. (Family-Anacardiaceae). In phytochemical screenings with the crude extractives demonstrated the presence of alkaloids, steroids, tannins, ...

Sustainable Utilisation of Non timber Forest Products

Sustainable Utilisation of Non timber Forest Products
  • Author : Mohd. Yaakub Hj. Johari,Maryati Mohamed,Mary Sintoh
  • Publisher : Unknown
  • Release Date : 1998
  • Total pages : 148
  • ISBN : 0128178914
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Summary : Read online Sustainable Utilisation of Non timber Forest Products written by Mohd. Yaakub Hj. Johari,Maryati Mohamed,Mary Sintoh, published by which was released on 1998. Download full Sustainable Utilisation of Non timber Forest Products Books now! Available in PDF, ePub and Kindle....

Intellectual Property Rights Naturally Derived Bioactive Compounds and Resource Conservation

Intellectual Property Rights  Naturally Derived Bioactive Compounds and Resource Conservation
  • Author : C. Gyllenhaal,N.R. Farnsworth,American Society of Pharmacognosy. Interim Meeting
  • Publisher : Elsevier Science Limited
  • Release Date : 1997-07-02
  • Total pages : 336
  • ISBN : 0128178914
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Summary : The tropical rain forests have become an important focus in the search for new drugs from natural sources, especially from plants. This volume aims to promote a better understanding between scientists and institutions located in the developed and developing countries, in their efforts to search for new medicinal agents from ...

Phytochemical Diversity

Phytochemical Diversity
  • Author : E. Chrystal
  • Publisher : Unknown
  • Release Date : 1997
  • Total pages : 254
  • ISBN : 0128178914
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Summary : While the study of the chemicals produced by plants is arguably one of the oldest of the natural product sciences, current global concerns regarding the disappearance of biodiversity, along with the availability of methodology for systematic genetic manipulation and plant tissue culture, have rekindled industrial interest in phytochemical screening. Phytochemical ...

Bioassay Methods in Natural Product Research and Drug Development

Bioassay Methods in Natural Product Research and Drug Development
  • Author : Lars Bohlin,Jan G. Bruhn
  • Publisher : Springer Science & Business Media
  • Release Date : 1999-01-31
  • Total pages : 201
  • ISBN : 0128178914
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Summary : Bioassay Methods in Natural Product Research and Drug Development contains the proceedings from the Phytochemical Society of Europe's very successful symposium on this topic, held August 24-27, 1997 in Uppsala, Sweden. In this volume, leading academic and industrial scientists discuss novel methods for assaying natural products to find new structure-activity relationships. ...

Current Organic Chemistry

Current Organic Chemistry
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 212
  • ISBN : 0128178914
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Summary : Provides in depth reviews on current progress in the fields of asymmetric synthesis, organometallic chemistry, bioorganic chemistry, heterocyclic chemistry, natural product chemistry, and analytical methods in organic chemistry. Each issue is edited by an appointed Executive Guest Editor...

Trease and Evans Pharmacognosy

Trease and Evans  Pharmacognosy
  • Author : William Charles Evans,George Edward Trease
  • Publisher : W B Saunders Company
  • Release Date : 1996
  • Total pages : 612
  • ISBN : 0128178914
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Summary : This reference covers the medicinal properties of plant and animal products. It seeks to maintain a balance between topical and classic aspects of the subject, and this edition includes an expanded section on complementary and traditional systems of medicine, taking in aromatherapy and Chinese and African medicine. This edition also ...