Pharmacology in Drug Discovery and Development

Written By Terry Kenakin
Pharmacology in Drug Discovery and Development
  • Publsiher : Academic Press
  • Release : 21 October 2016
  • ISBN : 0128037539
  • Pages : 350 pages
  • Rating : /5 from reviews
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Download or read book entitled Pharmacology in Drug Discovery and Development by author: Terry Kenakin which was release on 21 October 2016 and published by Academic Press with total page 350 pages . This book available in PDF, EPUB and Kindle Format. Pharmacology in Drug Discovery and Development: Understanding Drug Response, Second Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book allow for the application of more predictive pharmacological procedures aimed at increasing therapeutic efficacy that will lead to more successful drug development. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization. This edition has been fully revised to address the latest advances and research related to real time kinetic assays, pluridimensional efficacy, signaling bias, irreversible and chemical antagonism, allosterically-induced bias, pharmacokinetics and safety, target and pathway validation, and much more. With numerous valuable chapter summaries, detailed references, practical examples and case studies throughout, Dr. Kenakin successfully navigates a highly complex subject, making it accessible for students, professors, and new researchers working in pharmacology and drug discovery. Includes example-based cases that illustrate how the pharmacological concepts discussed in this book lead to practical outcomes for further research Provides vignettes on those researchers and scientists who have contributed significantly to the fields of pharmacology and drug discovery throughout history Offers sample questions throughout the book and an appendix containing answers for self-testing and retention

Pharmacology in Drug Discovery and Development

Pharmacology in Drug Discovery and Development
  • Author : Terry Kenakin
  • Publisher : Academic Press
  • Release Date : 2016-10-21
  • Total pages : 350
  • ISBN : 0128037539
GET BOOK

Summary : Pharmacology in Drug Discovery and Development: Understanding Drug Response, Second Edition, is an introductory resource illustrating how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. The concepts discussed in this book ...

Drug Discovery and Development E Book

Drug Discovery and Development   E Book
  • Author : Raymond G Hill
  • Publisher : Elsevier Health Sciences
  • Release Date : 2012-07-20
  • Total pages : 368
  • ISBN : 0128037539
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Summary : The modern pharmacopeia has enormous power to alleviate disease, and owes its existence almost entirely to the work of the pharmaceutical industry. This book provides an introduction to the way the industry goes about the discovery and development of new drugs. The first part gives a brief historical account from ...

Drug Discovery and Development Third Edition

Drug Discovery and Development  Third Edition
  • Author : James J. O'Donnell,John Somberg,Vincent Idemyor,James T. O'Donnell
  • Publisher : CRC Press
  • Release Date : 2019-11-21
  • Total pages : 668
  • ISBN : 0128037539
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Summary : Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of ...

Quantitative Molecular Pharmacology and Informatics in Drug Discovery

Quantitative Molecular Pharmacology and Informatics in Drug Discovery
  • Author : Michael Lutz,Terry Kenakin
  • Publisher : John Wiley & Sons
  • Release Date : 2000-01-10
  • Total pages : 428
  • ISBN : 0128037539
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Summary : Quantitative Molecular Pharmacology and Informatics in Drug Discovery Michael Lutz, Section Head, Cheminformatics Group and Terry Kenakin, Principal Research Scientist, Glaxo Wellcome Research and Development, Research Triangle Park, NC, USA Quantitative Molecular Pharmacology and Informatics in Drug Discovery combines pharmacology, genetics and statistics to provide a complete guide to the ...

Drug Discovery and Development Third Edition

Drug Discovery and Development  Third Edition
  • Author : James J. O'Donnell,John Somberg,Vincent Idemyor,James T. O'Donnell
  • Publisher : CRC Press
  • Release Date : 2019-12-13
  • Total pages : 668
  • ISBN : 0128037539
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Summary : Drug Discovery and Development, Third Edition presents up-to-date scientific information for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It explores many scientific advances in new drug discovery and development for areas such as screening technologies, biotechnology approaches, and evaluation of ...

Basic Principles of Drug Discovery and Development

Basic Principles of Drug Discovery and Development
  • Author : Benjamin Blass
  • Publisher : Academic Press
  • Release Date : 2015-04-28
  • Total pages : 580
  • ISBN : 0128037539
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Summary : Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, providing comprehensive explanations of enabling technologies such as high throughput screening, structure based drug design, molecular modeling, pharmaceutical profiling, and translational medicine, all areas that have become critical steps in ...

Drug Discovery and Evaluation Methods in Clinical Pharmacology

Drug Discovery and Evaluation  Methods in Clinical Pharmacology
  • Author : H.Gerhard Vogel,Jochen Maas,Alexander Gebauer
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-12-15
  • Total pages : 564
  • ISBN : 0128037539
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Summary : Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the potency compared to existing drugs have to be determined. As these ...

Case Studies in Modern Drug Discovery and Development

Case Studies in Modern Drug Discovery and Development
  • Author : Xianhai Huang,Robert G. Aslanian
  • Publisher : John Wiley & Sons
  • Release Date : 2012-04-19
  • Total pages : 472
  • ISBN : 0128037539
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Summary : Learn why some drug discovery and development efforts succeed . . . and others fail Written by international experts in drug discovery and development, this book sets forth carefully researched and analyzed case studies of both successful and failed drug discovery and development efforts, enabling medicinal chemists and pharmaceutical scientists to learn from ...

The Future of Drug Discovery

The Future of Drug Discovery
  • Author : Tamas Bartfai,Graham V. Lees
  • Publisher : Academic Press
  • Release Date : 2013
  • Total pages : 346
  • ISBN : 0128037539
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Summary : The Future of Drug Discovery: Who decides which diseases to treat? provides a timely and detailed look at the efforts of the pharmaceutical industry and how they relate, or should relate, to societal needs. The authors posit that as a result of increasing risk aversion and accelerated savings in research ...

Successful Drug Discovery

Successful Drug Discovery
  • Author : János Fischer,Wayne E. Childers
  • Publisher : John Wiley & Sons
  • Release Date : 2016-11-04
  • Total pages : 292
  • ISBN : 0128037539
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Summary : Retaining the successful approach found in the previous volume in this series, the inventors and primary developers of drugs that successfully made it to market tell the story of the drug's discovery and development and relate the often twisted route from the first candidate molecule to the final marketed drug. 11 ...

Pharmacological Advances in Natural Product Drug Discovery

Pharmacological Advances in Natural Product Drug Discovery
  • Author : Guanhua Du
  • Publisher : Academic Press
  • Release Date : 2020-03
  • Total pages : 312
  • ISBN : 0128037539
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Summary : Pharmacological Advances in Natural Product Drug Discovery, Volume 87 in the Advances in Pharmacology series, presents the latest pharmacological research progresses of 8 medicinal compounds from natural products, including salvianolic acid, tanshinone, paeonol, chlorogenic acid, astragaloside, icariin, ganoderan, and febrifugine. Specific chapters to this new release include Potential Role of Paeonol on ...

Social Aspects of Drug Discovery Development and Commercialization

Social Aspects of Drug Discovery  Development and Commercialization
  • Author : Odilia Osakwe,Syed A.A. Rizvi
  • Publisher : Academic Press
  • Release Date : 2016-02-18
  • Total pages : 324
  • ISBN : 0128037539
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Summary : Social Aspects of Drug Discovery, Development and Commercialization provides an insightful analysis of the drug discovery and development landscape as it relates to society. This book examines the scientific, legal, philosophical, economic, political, ethical and cultural factors that contribute to drug development. The pharmaceutical industry is under scrutiny to develop ...

Drug Discovery and Development E Book

Drug Discovery and Development E Book
  • Author : Raymond G Hill,Duncan Richards
  • Publisher : Elsevier Health Sciences
  • Release Date : 2021-07-27
  • Total pages : 384
  • ISBN : 0128037539
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Summary : With unprecedented interest in the power that the modern therapeutic armamentarium has to combat disease, the new edition of Drug Discovery and Development is an essential resource for anyone interested in understanding how drugs and other therapeutic interventions are discovered and developed, through to clinical research, registration, and market access. ...

Pharmacology for Chemists

Pharmacology for Chemists
  • Author : Tom Blackburn,Terry Kenakin,Raymond Hill
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-10-25
  • Total pages : 524
  • ISBN : 0128037539
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Summary : Assuming little previous knowledge of biology, this book aids graduate chemists to close the gap in their knowledge of pharmacology and make the link between medicinal chemistry and the way in which drugs act on the body. The availability of receptor structures has revolutionized drug discovery and development necessitating an ...

Drug Discovery and Clinical Research

Drug Discovery and Clinical Research
  • Author : SK Gupta
  • Publisher : JP Medical Ltd
  • Release Date : 2011-06-01
  • Total pages : 668
  • ISBN : 0128037539
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Summary : The Drug Discovery and Clinical Research bandwagon has been joined by scientists and researchers from all fields including basic sciences, medical sciences, biophysicists, biotechnologists, statisticians, regulatory officials and many more. The joint effort and contribution from all is translating into the fast development of this multi-faceted field. At the same ...