Personalized Immunosuppression in Transplantation

Written By Michael Oellerich
Personalized Immunosuppression in Transplantation
  • Publsiher : Elsevier
  • Release : 08 August 2015
  • ISBN : 0128011335
  • Pages : 316 pages
  • Rating : /5 from reviews
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Download or read book entitled Personalized Immunosuppression in Transplantation by author: Michael Oellerich which was release on 08 August 2015 and published by Elsevier with total page 316 pages . This book available in PDF, EPUB and Kindle Format. Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring. The book is written for pathologists, toxicologists, and transplant surgeons who are involved in the management of transplant patients, offering them in-depth coverage of the management of immunosuppressant therapy in transplant patients with the goal of maximum benefit from drug therapy and minimal risk of drug toxicity. This book also provides practical guidelines for managing immunosuppressant therapy, including the therapeutic ranges of various immunosuppressants, the pitfalls of methodologies used for determination of these immunosuppressants in whole blood or plasma, appropriate pharmacogenomics testing for organ transplant recipients, and when biomarker monitoring could be helpful. Focuses on the personalized management of immunosuppression therapy in individual transplant patients Presents information that applies to many areas, including gmass spectrometry, assay design, assay validation, clinical chemistry, and clinical pathology Provides practical guidelines for the initial selection and subsequent modifications of immunosuppression therapy in individual transplant patients Reviews the latest research in biomarker monitoring in personalizing immunosuppressant therapy, including potential new markers not currently used, but with great potential for future use Explains how monitoring graft-derived, circulating, cell free DNA has shown promise in the early detection of transplant injury in liquid biopsy

Personalized Immunosuppression in Transplantation

Personalized Immunosuppression in Transplantation
  • Author : Michael Oellerich,Amitava Dasgupta
  • Publisher : Elsevier
  • Release Date : 2015-08-08
  • Total pages : 316
  • ISBN : 0128011335
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Summary : Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring. The book is written for pathologists, toxicologists, and transplant surgeons who ...

Textbook of Personalized Medicine

Textbook of Personalized Medicine
  • Author : Kewal K. Jain
  • Publisher : Springer Nature
  • Release Date : 2020-12-05
  • Total pages : 744
  • ISBN : 0128011335
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Summary : This book is for personalized medicine as a prescription of specific treatments and therapeutics best suited for an individual and considers genetic as well as environmental factors that influence responses to therapy. Best approaches are described for integration of all available technologies for optimizing the therapy of individual patients. This ...

Essentials of Genomic and Personalized Medicine

Essentials of Genomic and Personalized Medicine
  • Author : Geoffrey S. Ginsburg,Huntington F Willard
  • Publisher : Academic Press
  • Release Date : 2009-10-02
  • Total pages : 850
  • ISBN : 0128011335
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Summary : Derived from the comprehensive two-volume set, Genomic and Personalized Medicine also edited by Drs. Willard and Ginsburg, this work serves the needs of the evolving population of scientists, researchers, practitioners and students that are embracing one of the most promising avenues for advances in diagnosis, prevention and treatment of human ...

Gastrointestinal Transplantation An Issue of Gastroenterology Clinics of North America E Book

Gastrointestinal Transplantation  An Issue of Gastroenterology Clinics of North America  E Book
  • Author : Enrico Benedetti,Ivo G. Tzvetanov
  • Publisher : Elsevier Health Sciences
  • Release Date : 2018-05-16
  • Total pages : 212
  • ISBN : 0128011335
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Summary : The Guest Editors have put together a concise monograph on the latest advances in transplantation of the liver, intestine, and pancreas. Expert authors have written comprehensive reviews on the following topics: Living donor liver transplantation: Technical innovations; Liver transplantation for cholangiocarcinoma; Immunological monitoring to personalize immunosuppression after liver transplantation; Status ...

Disease Recurrence After Liver Transplantation

Disease Recurrence After Liver Transplantation
  • Author : Paul J. Thuluvath
  • Publisher : Springer
  • Release Date : 2015-11-11
  • Total pages : 269
  • ISBN : 0128011335
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Summary : As there is a high incidence of disease recurrence after liver transplantation, this volume is designed around the need for a reference text dealing exclusively with this problem. The book places special emphasis on pre- and post-transplant predictors of recurrence, severity assessment, prophylaxis, and treatment. Pathobiology of disease recurrence is ...

Gene Polymorphisms of Immunosuppressants in Solid Organ Transplantation

Gene Polymorphisms of Immunosuppressants in Solid Organ Transplantation
  • Author : Yingzi Ming
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 0128011335
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Summary : The rapid development of immunosuppressants (IS) has already improved the prognosis of recipients post solid organ transplantation (SOT) in the past decades. However, the individual difference in IS metabolism may lead to either rejection or drug toxicity, thus suggesting the importance of personalized therapy. Gene polymorphisms (GP) regarding metabolic enzymes ...

Drug Benefits and Risks

Drug Benefits and Risks
  • Author : Christoffel Jos van Boxtel,Budiono Santoso,I. Ralph Edwards
  • Publisher : IOS Press
  • Release Date : 2008-01-01
  • Total pages : 821
  • ISBN : 0128011335
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Summary : Explores the scientific basis and practice of drug therapy. This book examines the practice of clinical pharmacology and pharmacotherapy in the developing as well as the developed world. It covers general clinical pharmacology, pharmacology of various drug groups and the treatments specific to various diseases....

Transplantation An Issue of Anesthesiology Clinics

Transplantation  An Issue of Anesthesiology Clinics
  • Author : Aman Mahajan,Christopher Wray
  • Publisher : Elsevier Health Sciences
  • Release Date : 2017-08-31
  • Total pages : 212
  • ISBN : 0128011335
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Summary : This issue of Anesthesiology Clinics focuses on Transplantation. Editors Aman Mahajan and Christopher Wray have assembled an expert team of authors on topics such as: Immunology and Pharmacology of Transplantation; Infectious Diseases and Malignancies in Transplantation; Anesthesia Management of the Organ Donor; Transfusion Medicine and Coagulation Management in Organ Transplantation; ...

Metabolic Drug Interactions with Immunosuppressants

Metabolic Drug Interactions with Immunosuppressants
  • Author : Katalin Monostory
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 0128011335
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Summary : Organ transplantation has become a routine clinical practice for patients with end-stage disease of liver, kidney, heart, or lung. Although improved immunosuppressant therapy substantially contributes to the success of transplantation, clinicians continue to face challenges because of wide interindividual variations in blood concentrations resulting in subtherapeutic or supratherapeutic levels. Many ...

Pediatric Liver Transplantation E Book

Pediatric Liver Transplantation E Book
  • Author : Nedim Hadzic,Ulrich Baumann,Valérie MCLIN
  • Publisher : Elsevier Health Sciences
  • Release Date : 2020-11-13
  • Total pages : 512
  • ISBN : 0128011335
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Summary : Written and edited by global leaders in the field, Pediatric Liver Transplantation: A Clinical Guide covers all aspects of treatment and management regarding this multifaceted procedure and unique patient population. This practical reference offers detailed, focused guidance in a highly templated, easy-to-consult format, covering everything from pre-transplantation preparation to surgical ...

Biomarkers of Renal Diseases

Biomarkers of Renal Diseases
  • Author : Joaquín García-Estañ,Felix Vargas
  • Publisher : MDPI
  • Release Date : 2021-01-19
  • Total pages : 276
  • ISBN : 0128011335
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Summary : This book provides important and updated information on current research devoted to urinary biomarkers. Urinary biomarkers are characteristics that can be objectively measured and evaluated as indicators of normal biological or pathogenic processes of pharmacological responses to therapeutic intervention....

Genomic and Personalized Medicine

Genomic and Personalized Medicine
  • Author : Geoffrey S. Ginsburg,Huntington F. Willard
  • Publisher : Academic Press
  • Release Date : 2012-11-15
  • Total pages : 1350
  • ISBN : 0128011335
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Summary : This two-volume set provides an in-depth look at one of the most promising avenues for advances in the diagnosis, prevention and treatment of human disease. The inclusion of the latest information on diagnostic testing, population screening, predicting disease susceptibility, pharmacogenomics and more presents this book as an essential tool for ...

Clinical Guide to Heart Transplantation

Clinical Guide to Heart Transplantation
  • Author : Jon Kobashigawa
  • Publisher : Springer
  • Release Date : 2017-03-29
  • Total pages : 258
  • ISBN : 0128011335
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Summary : This is a concise review of up-to-date concepts and techniques in the discipline of heart transplantation. It is a review and reference for practitioners managing patients with advanced heart disease, including patients with end-stage heart failure, mechanical circulatory support or transplant recipients. Heart failure is a major public health issue, ...

Metabolic Phenotyping in Personalized and Public Healthcare

Metabolic Phenotyping in Personalized and Public Healthcare
  • Author : Jeremy Nicholson,Ara Darzi,Elaine Holmes,John C. Lindon
  • Publisher : Academic Press
  • Release Date : 2016-02-11
  • Total pages : 428
  • ISBN : 0128011335
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Summary : Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches. In order to achieve that objective, a deep personal description is required at the level of ...

Principles of Immunopharmacology

Principles of Immunopharmacology
  • Author : Frans P. Nijkamp,Michael J. Parnham
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-09-01
  • Total pages : 728
  • ISBN : 0128011335
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Summary : This textbook provides a unique support in gaining essential knowledge on the immune response, its diagnosis and its modification by drugs and chemicals. The first section of the book, covering a basic introduction to immunology and its relevance for human disease, has been updated to accommodate new immunological concepts. The ...