Parkinson s Disease

Written By Richard Nass
Parkinson s Disease
  • Publsiher : Academic Press
  • Release : 20 June 2021
  • ISBN : 9780123740281
  • Pages : 652 pages
  • Rating : /5 from reviews
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Download or read book entitled Parkinson s Disease by author: Richard Nass which was release on 20 June 2021 and published by Academic Press with total page 652 pages . This book available in PDF, EPUB and Kindle Format. Parkinson's disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder has remained elusive. Confounding this issue is the lack of experimental models that completely recapitulate the disease state. The identification of a number of genes thought to play a role in the cell death, and development of both toxin and genetic models to explore the function of the genes both in unaffected and diseased cells are now providing new insights into the molecular basis of the neurodegeneration, as well as therapeutic approaches. In this reference, we will describe the advances and the advantages that various invertebrates, cell culture, rodents, and mammals provide in the identification of the molecular components and mechanisms involved in the cell death, and outline the opportunities that these systems provide in drug discovery. * Comprehensive and critical assessment of the utility of various model systems to identify the molecular components and pathways involved in Parkinson's disease * Describes the power of toxin and genetic models to identify novel therapeutic targets and compounds that can be used in PD * Current overviews of current status of PD research and discovery from bench-to-bedside * Provides novel insights and views on where the future of PD research may lead * Provides a powerful teaching tool and template to explore the utility of model systems to identify molecular pathways, molecular targets, and therapeutics that are applicable to a variety of neurological diseases

Parkinson s Disease

Parkinson s Disease
  • Author : Sarat Chandra Yenisetti
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-05-30
  • Total pages : 126
  • ISBN : 9780123740281
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Summary : Parkinson's disease (PD) is the second most common neurodegenerative disorder results due to loss of dopamine producing brain cells. Knowledge relating to PD condition has been known since 5000BC, however no effective therapeutic strategies are available till today. Therefore it is important for neurobiologists to work further by taking advantage ...

Parkinson s Disease

Parkinson s Disease
  • Author : Richard Nass,Serge Przedborski
  • Publisher : Academic Press
  • Release Date : 2008
  • Total pages : 652
  • ISBN : 9780123740281
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Summary : Parkinson's disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder has remained elusive. Confounding this issue is ...

Basic Clinical and Therapeutic Aspects of Alzheimer s and Parkinson s Diseases

Basic  Clinical  and Therapeutic Aspects of Alzheimer   s and Parkinson   s Diseases
  • Author : Toshiharu Nagatsu,Abraham Fisher,Mitsuo Yoshida
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 830
  • ISBN : 9780123740281
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Summary : This two-volume work contains the full text of the oral and poster presentations and the general discussion at the round table discussion of the Second International Conference on Alzheimer's and Parkinson's Diseases: Basic and Therapeutic Strategies, held at the Kyoto Park Hotel in Kyoto, Japan, on November 6-10, 1989. The First ...

Parkinson s Disease

Parkinson   s Disease
  • Author : F. Messiha
  • Publisher : Springer
  • Release Date : 2012-07-12
  • Total pages : 316
  • ISBN : 9780123740281
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Summary : These Proceedings are the outcome of the First Tarbox Parkinson's Disease Symposium held October 14-16, 1976, at the South Park Inn in Lubbock, Texas. The Symposium was sponsored by the Department of Pharmacology and Therapeutics and the Tarbox Parkinson's Disease In stitute of the Texas Tech University School of Medicine at ...

Improving Therapeutics for Parkinson s Disease

Improving Therapeutics for Parkinson s Disease
  • Author : Jennifer A. O'Malley
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 394
  • ISBN : 9780123740281
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Summary : The following results are from studies designed with the overall goal of elucidating means for improving therapeutics for Parkinson's disease. There is still much to be understood regarding the cellular and molecular mechanisms underlying the development of side effects to therapies for Parkinson's disease such as levodopa-induced dyskinesias. Additionally, therapeutic ...

Therapeutics of Parkinson s Disease and Other Movement Disorders

Therapeutics of Parkinson s Disease and Other Movement Disorders
  • Author : Mark Hallett,Werner Poewe
  • Publisher : John Wiley & Sons
  • Release Date : 2008-10-13
  • Total pages : 520
  • ISBN : 9780123740281
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Summary : Provides a comprehensive update on therapies for Parkinson’s disease and other movement disorders Describes the basic mechanisms of neurodegeneration, pharmacologic interventions for motor and non-motor symptoms, and surgical management Features summary tables and algorithms that serve as a quick reference guide for practical treatment decisions The expert guidance of ...

Parkinson s Disease Therapeutics

Parkinson   s Disease Therapeutics
  • Author : Magisetty Obulesu
  • Publisher : Academic Press
  • Release Date : 2020-01-30
  • Total pages : 146
  • ISBN : 9780123740281
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Summary : Parkinson’s Disease Therapeutics: Emphasis on Nanotechnological Advances presents the latest information on the second most common neurodegenerative disorder in the elderly. Despite remarkable progress in various PD therapeutics, such as microRNAs and brain drug delivery systems, a few limitations impede their success. This book sheds light on the pros ...

Handbook of Parkinson s Disease Fifth Edition

Handbook of Parkinson s Disease  Fifth Edition
  • Author : Rajesh Pahwa,Kelly E. Lyons Ph.D.
  • Publisher : CRC Press
  • Release Date : 2013-05-09
  • Total pages : 619
  • ISBN : 9780123740281
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Summary : Highly Commended, BMA Medical Book Awards 2014 This volume has long prevailed as one of the leading resources on Parkinson's disease (PD). Fully updated with practical and engaging chapters on pathology, neurochemistry, etiology, and breakthrough research, this source spans every essential topic related to the identification, assessment, and treatment of PD. ...

Towards New Therapies for Parkinson s Disease

Towards New Therapies for Parkinson s Disease
  • Author : David Finkelstein
  • Publisher : BoD – Books on Demand
  • Release Date : 2011-11-02
  • Total pages : 410
  • ISBN : 9780123740281
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Summary : Parkinson's disease (PD) is characterised clinically by various non-motor and progressive motor symptoms, pathologically by loss of dopamine producing cells and intraneuronal cytoplasmic inclusions composed primarily of ?-synuclein. By the time a patient first presents with symptoms of Parkinson's disease at the clinic, a significant proportion of the cells in ...

Parkinson s Disease Therapeutics

Parkinson s Disease Therapeutics
  • Author : Magisetty Obulesu
  • Publisher : Academic Press
  • Release Date : 2020-01-24
  • Total pages : 200
  • ISBN : 9780123740281
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Summary : Parkinson's Disease is the second most common neurodegenerative disorder in the elderly. Vital pathological events include a decline in nigrostriatal neurons and deterioration of the neurotransmitter dopamine. Since amyloid fibrils are the key end products of several proteins implicated in neurodegenerative diseases, multiple studies emphasize their diagnosis as the mainstay ...

The New Parkinson s Disease Treatment Book

The New Parkinson s Disease Treatment Book
  • Author : J. Eric Ahlskog (MD, PhD.),J. Eric Ahlskog
  • Publisher : Oxford University Press, USA
  • Release Date : 2015-08-06
  • Total pages : 544
  • ISBN : 9780123740281
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Summary : As many as one million Americans, including Michael J. Fox and Muhammad Ali, suffer from Parkinson's Disease. Now, a leader in the fight against Parkinson's, Dr. J. Eric Ahlskog of the Mayo Clinic, has revised and updated his definitive guide for patients and their families. Dr. Ahlskog offers a crystal-clear, ...

Encyclopedia of Parkinson s Disease

Encyclopedia of Parkinson s Disease
  • Author : Kate White
  • Publisher : Hayle Medical
  • Release Date : 2015-02-17
  • Total pages : 216
  • ISBN : 9780123740281
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Summary : Various therapeutic modalities and treatments of Parkinson's disease (PD) have been described in this book. This disease is caused mainly due to the death of dopaminergic neurons in the substantia nigra. Recent PD medications treat symptoms; though none decrease the rate of dopaminergic neuron degeneration. The primary problem in development ...

Parkinson s Disease Current and Future Therapeutics and Clinical Trials

Parkinson s Disease  Current and Future Therapeutics and Clinical Trials
  • Author : Nestor Galvez-Jimenez,Hubert H. Fernandez,Alberto J. Espay,Susan H. Fox
  • Publisher : Cambridge University Press
  • Release Date : 2016-03-31
  • Total pages : 384
  • ISBN : 9780123740281
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Summary : This book emphasizes treatment options for Parkinson's disease, providing the necessary clinical and scientific basis for the foundations of solid therapeutics....

Peripheral Immunity in Parkinson s Disease Emerging Role and Novel Target for Therapeutics

Peripheral Immunity in Parkinson s Disease  Emerging Role and Novel Target for Therapeutics
  • Author : Cristoforo Comi,Marco Cosentino,Rodrigo Pacheco
  • Publisher : Frontiers Media SA
  • Release Date : 2019-12-23
  • Total pages : 212
  • ISBN : 9780123740281
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Summary : Read online Peripheral Immunity in Parkinson s Disease Emerging Role and Novel Target for Therapeutics written by Cristoforo Comi,Marco Cosentino,Rodrigo Pacheco, published by Frontiers Media SA which was released on 2019-12-23. Download full Peripheral Immunity in Parkinson s Disease Emerging Role and Novel Target for Therapeutics Books ...

10 Breakthrough Therapies for Parkinson s Disease

10 Breakthrough Therapies for Parkinson s Disease
  • Author : Michael Okun
  • Publisher : Books4patients
  • Release Date : 2015-08-21
  • Total pages : 156
  • ISBN : 9780123740281
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Summary : Michael S. Okun, M.D. is internationally celebrated as both a neurologist and a leading researcher. He has often been referred to as, "the voice of the Parkinson's disease patient." He was honored at the White House in 2015 as a Champion of Change for Parkinson's disease. He has an international ...