Overcoming Cancers Resistant to Her-2 Antibodies
  • Release Date : 15 December 2019
  • Publisher : Sensitizing Agents for Cancer
  • Genre : Medical
  • Pages : 250 pages
  • ISBN 13 : 0128164085
Ratings: 4
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Download or read book entitled Overcoming Cancers Resistant to Her-2 Antibodies by author: Benjamin Bonavida which was release on 15 December 2019 and published by Sensitizing Agents for Cancer with total page 250 pages . This book available in PDF, EPUB and Kindle Format. Overcoming Cancers Resistant to HER-2 Antibodies provides general updated information on the resistance of various human cancers to anti-HER2 therapeutic antibodies. It also discusses the description of various sensitizing agents that can reverse resistance when used in combination with anti-HER2 antibodies.There have been a lot of reports in which the treatment with anti-HER2 antibodies for various cancers has resulted in clinical responses; however, there have been also subsets of cancer patients who did not respond initially, and several responding patients developed resistance following treatments. Therefore, the use of various immunosensitizing agents to reverse resistance has been considered and this book discusses each of them in depth, such as Lapatinib, Ganetespib, Paclitaxel, Celecoxib, Emantasine, Liposomal Doxorubicin, and Kinase Inhibitors. This book is a valuable source for cancer researchers, oncologists, pharmacologists and different members of biomedical field interested in fighting cancer resistance to HER-2 antibodies. Provides a general summary of various sensitizing agents that can work effectively when used in combination with anti-HER2 antibodies to reverse resistance Offers potential underlying mechanisms by which the cancer cells are either inherently resistant or become unresponsive to antibody treatment Discusses how to develop new targeted agents to underlie resistance in order to expand research on this field