Novel Designs of Early Phase Trials for Cancer Therapeutics

Written By Shivaani Kummar
Novel Designs of Early Phase Trials for Cancer Therapeutics
  • Publsiher : Academic Press
  • Release : 22 May 2018
  • ISBN : 0128125705
  • Pages : 234 pages
  • Rating : /5 from reviews
GET THIS BOOKNovel Designs of Early Phase Trials for Cancer Therapeutics


Download or read book entitled Novel Designs of Early Phase Trials for Cancer Therapeutics by author: Shivaani Kummar which was release on 22 May 2018 and published by Academic Press with total page 234 pages . This book available in PDF, EPUB and Kindle Format. Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses topics such as statistical perspectives on cohort expansions, the role and application of molecular profiling and how to integrate biomarkers in early phase trials. Additionally, it discusses how to incorporate patient reported outcomes in phase one trials. This book is a valuable resource for medical oncologists, basic and translational biomedical scientists, and trainees in oncology and pharmacology who are interested in learning how to improve their research by using early phase trials. Brings a comprehensive review and recommendations for new clinical trial designs for modern cancer therapeutics Provides the reader with a better understanding on how to design and implement early phase oncology trials Presents a better and updated understanding of the process of developing new treatments for cancer, the exciting scientific advances and how they are informing drug development

Novel Designs of Early Phase Trials for Cancer Therapeutics

Novel Designs of Early Phase Trials for Cancer Therapeutics
  • Author : Shivaani Kummar,Chris Takimoto
  • Publisher : Academic Press
  • Release Date : 2018-05-22
  • Total pages : 234
  • ISBN : 0128125705
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Summary : Novel Designs of Early Phase Trials for Cancer Therapeutics provides a comprehensive review by leaders in the field of the process of drug development, the integration of molecular profiling, the changes in early phase trial designs, and endpoints to optimally develop a new generation of cancer therapeutics. The book discusses ...

Oncology Clinical Trials

Oncology Clinical Trials
  • Author : Susan Halabi, PhD,Wm. Kevin Kelly, DO
  • Publisher : Demos Medical Publishing
  • Release Date : 2009-12-22
  • Total pages : 168
  • ISBN : 0128125705
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Summary : Clinical trials are the engine of progress in the development of new drugs and devices for the detection, monitoring, prevention and treatment of cancer. A well conceived, carefully designed and efficiently conducted clinical trial can produce results that change clinical practice overnight, deliver new oncology drugs and diagnostics to the ...

Phase I Oncology Drug Development

Phase I Oncology Drug Development
  • Author : Timothy A. Yap,Jordi Rodon,David S. Hong
  • Publisher : Springer Nature
  • Release Date : 2020-10-18
  • Total pages : 352
  • ISBN : 0128125705
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Summary : This book provides a detailed review of how oncology drug development has changed over the past decade, and serves as a comprehensive guide for the practicalities in setting up phase I trials. The book covers strategies to accelerate the development of novel antitumor compounds from the laboratory to clinical trials ...

Cancer Clinical Trials

Cancer Clinical Trials
  • Author : Stephen L. George,Xiaofei Wang,Herbert Pang
  • Publisher : CRC Press
  • Release Date : 2016-08-19
  • Total pages : 474
  • ISBN : 0128125705
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Summary : Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis provides statisticians with an understanding of the critical challenges currently encountered in oncology trials. Well-known statisticians from academic institutions, regulatory and government agencies (such as the U.S. FDA and National Cancer Institute), and the pharmaceutical industry share their ...

Dose Finding Designs for Early Phase Cancer Clinical Trials

Dose Finding Designs for Early Phase Cancer Clinical Trials
  • Author : Takashi Daimon,Akihiro Hirakawa,Shigeyuki Matsui
  • Publisher : Springer
  • Release Date : 2019-05-21
  • Total pages : 133
  • ISBN : 0128125705
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Summary : This book provides a comprehensive introduction to statistical methods for designing early phase dose-finding clinical trials. It will serve as a textbook or handbook for graduate students and practitioners in biostatistics and clinical investigators who are involved in designing, conducting, monitoring, and analyzing dose-finding trials. The book will also provide ...

Oncology Clinical Trials

Oncology Clinical Trials
  • Author : William Kevin Kelly, DO,Susan Halabi, PhD
  • Publisher : Springer Publishing Company
  • Release Date : 2018-03-28
  • Total pages : 600
  • ISBN : 0128125705
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Summary : The second edition of Oncology Clinical Trials has been thoroughly revised and updated and now contains the latest designs and methods of conducting and analyzing cancer clinical trials in the era of precision medicine with biologic agents—including trials investigating the safety and efficacy of targeted therapies, immunotherapies, and combination ...

Handbook of Statistics in Clinical Oncology

Handbook of Statistics in Clinical Oncology
  • Author : John Crowley,Antje Hoering
  • Publisher : CRC Press
  • Release Date : 2012-03-26
  • Total pages : 658
  • ISBN : 0128125705
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Summary : Many new challenges have arisen in the area of oncology clinical trials. New cancer therapies are often based on cytostatic or targeted agents, which pose new challenges in the design and analysis of all phases of trials. The literature on adaptive trial designs and early stopping has been exploding. Inclusion ...

Statistical Approaches in Oncology Clinical Development

Statistical Approaches in Oncology Clinical Development
  • Author : Satrajit Roychoudhury,Soumi Lahiri
  • Publisher : CRC Press
  • Release Date : 2018-03
  • Total pages : 316
  • ISBN : 0128125705
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Summary : Statistical Challenges in Oncology Clinical Development presents an overview of statistical considerations in oncology clinical trials, including both early and late phase of development. It illustrates how the novel statistical methods can enrich the design and analysis of modern oncology trials. The book covers wide spectrum of statistical methodology with ...

Clinical Trial Design

Clinical Trial Design
  • Author : Guosheng Yin
  • Publisher : John Wiley & Sons
  • Release Date : 2013-06-07
  • Total pages : 364
  • ISBN : 0128125705
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Summary : A balanced treatment of the theories, methodologies, and designissues involved in clinical trials using statisticalmethods There has been enormous interest and development in Bayesianadaptive designs, especially for early phases of clinical trials.However, for phase III trials, frequentist methods still play adominant role through controlling type I and type II ...

The Journal of Alternative and Complementary Medicine

The Journal of Alternative and Complementary Medicine
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 212
  • ISBN : 0128125705
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Summary : Read online The Journal of Alternative and Complementary Medicine written by , published by which was released on 2007. Download full The Journal of Alternative and Complementary Medicine Books now! Available in PDF, ePub and Kindle....

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
  • Author : Michelle A. Rudek,Cindy H. Chau,William D. Figg,Howard L. McLeod
  • Publisher : Springer Science & Business Media
  • Release Date : 2014-01-10
  • Total pages : 836
  • ISBN : 0128125705
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Summary : There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and ...

Cancer New Insights for the Healthcare Professional 2011 Edition

Cancer  New Insights for the Healthcare Professional  2011 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-01-09
  • Total pages : 3937
  • ISBN : 0128125705
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Summary : Cancer: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer. The editors have built Cancer: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer in this eBook ...

Research Report

Research Report
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1999
  • Total pages : 212
  • ISBN : 0128125705
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Summary : Read online Research Report written by , published by which was released on 1999. Download full Research Report Books now! Available in PDF, ePub and Kindle....

Oncology

Oncology
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 212
  • ISBN : 0128125705
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Summary : Read online Oncology written by , published by which was released on 2000. Download full Oncology Books now! Available in PDF, ePub and Kindle....

Clinical Trials

Clinical Trials
  • Author : Steven Piantadosi
  • Publisher : John Wiley & Sons
  • Release Date : 2017-08-28
  • Total pages : 920
  • ISBN : 0128125705
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Summary : Presents elements of clinical trial methods that are essential in planning, designing, conducting, analyzing, and interpreting clinical trials with the goal of improving the evidence derived from these important studies This Third Edition builds on the text’s reputation as a straightforward, detailed, and authoritative presentation of quantitative methods for ...