Nonsense Mutation Correction in Human Diseases

Written By Fabrice Lejeune
Nonsense Mutation Correction in Human Diseases
  • Publsiher : Academic Press
  • Release : 26 February 2016
  • ISBN : 0128044691
  • Pages : 190 pages
  • Rating : /5 from reviews
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Download or read book entitled Nonsense Mutation Correction in Human Diseases by author: Fabrice Lejeune which was release on 26 February 2016 and published by Academic Press with total page 190 pages . This book available in PDF, EPUB and Kindle Format. Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD). It presents the mechanism of action and rationale associated with each strategy to correct nonsense mutations with the results of clinical trials to further support this basis. In addition, the book shows how it may be possible to combine several of these strategies to ultimately improve the efficiency of correction, also suggesting the future goals and objectives to improve treatment modalities in this evolving sphere of personalized medicine. Features basic biological and clinical constructs that inform the application of genomic data to clinical decision-making Includes theories and methods that can be used to link bio-molecular and clinical phenotypes so as to enable integrative hypothesis discovery, testing, and downstream evidence-based practice Provides design patterns and use cases that contextualize the clinical decision-making and evidence-based practice relative to real world requirements and stakeholders

Nonsense Mutation Correction in Human Diseases

Nonsense Mutation Correction in Human Diseases
  • Author : Fabrice Lejeune,Hana Benhabiles,Jieshuang Jia
  • Publisher : Academic Press
  • Release Date : 2016-02-26
  • Total pages : 190
  • ISBN : 0128044691
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Summary : Nonsense Mutation Correction in Human Diseases: An Approach for Targeted Medicine provides an introduction on genetic diseases, discusses the prevalence of nonsense mutations, the consequences of a nonsense mutation for the expression of the mutant gene, and the presentation of the nonsense-mediated mRNA decay (NMD). It presents the mechanism of ...

Nature Encyclopedia of the Human Genome

Nature Encyclopedia of the Human Genome
  • Author : David N. Cooper
  • Publisher : Natures Pub Limited
  • Release Date : 2003
  • Total pages : 1135
  • ISBN : 0128044691
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Summary : Nature Encyclopedia of the Human Genome is the only reference resource devoted entirely to the scientific basis and genetics and genomics research and the complex commercial, philosophical, and ethical questions that arise from it. It presents a comprehensive and rigorously detailed overview of current genome science and its groundbreaking applications, ...

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  • Publisher : Unknown
  • Release Date : 2000
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  • ISBN : 0128044691
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Summary : Read online Genetics Abstracts written by , published by which was released on 2000. Download full Genetics Abstracts Books now! Available in PDF, ePub and Kindle....

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  • Release Date : 2012-01-31
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  • ISBN : 0128044691
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Summary : The main objective of this book is to provide a comprehensive review on stem cells and their role in tissue regeneration, homeostasis and therapy. In addition, the role of cancer stem cells in cancer initiation, progression and drug resistance are discussed. The cell signaling pathways and microRNA regulating stem cell ...

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Summary : Read online Chemical Abstracts written by , published by which was released on 2002. Download full Chemical Abstracts Books now! Available in PDF, ePub and Kindle....

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  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1995
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  • ISBN : 0128044691
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Summary : Read online Thrombosis and Haemostasis written by , published by which was released on 1995. Download full Thrombosis and Haemostasis Books now! Available in PDF, ePub and Kindle....

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  • Author : National Academy of Sciences (U.S.)
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 212
  • ISBN : 0128044691
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Summary : Read online Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.), published by which was released on 2007. Download full Proceedings of the National Academy of Sciences of the United States of America Books now! Available in PDF, ePub ...

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  • Publisher : Unknown
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  • ISBN : 0128044691
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Summary : Be cool in Italian! Perfect for kids eight- to fourteen-years old, Way-Cool Italian covers the latest in kid language as it is spoken in the Italian-speaking world. Inside you will find out how kids in another country talk about their computers, how they text each other, and how they speak ...

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  • Publisher : John Wiley & Sons Incorporated
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Summary : Rapid progress has been made in the understanding of the basic concepts of the immune response at biochemical and molecular levels. This text reviews the development of innovative techniques for diagnosing disorders at a very early stage and for detecting their carrier states and discusses novel therapeutic approaches such as ...

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Summary : Read online Liver and Biliary Diseases written by Neil Kaplowitz, published by which was released on 1996. Download full Liver and Biliary Diseases Books now! Available in PDF, ePub and Kindle....

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  • ISBN : 0128044691
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Summary : Updated and expanded for its Second Edition, this volume offers practical guidance in the diagnosis and treatment of motor disorders. The book brings together, in one convenient source, the entire spectrum of motor disorders caused by various etiologies. Seventeen new chapters cover vertigo and vestibular disorders; laryngeal motor disorders; facioscapulohumeral ...

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The Metabolic   Molecular Bases of Inherited Disease
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  • Publisher : New York ; Montreal : McGraw-Hill
  • Release Date : 2001
  • Total pages : 6338
  • ISBN : 0128044691
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Summary : Presents clinical, biochemical, and genetic information concerning those metabolic anomalies grouped under inborn errors of metabolism....

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Principles of Child Neurology
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  • Publisher : McGraw-Hill
  • Release Date : 1996
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Summary : Principles of Child Neurology is a comprehensive textbook on the diagnosis and management of neurologic disorders affecting neonates, infants, children, and adolescents. Patterned after Adams and Victor's Principles of Neurology, this text begins with ``Approach to the Patient,'' then details the cardinal manifestations and the major disease categories for ...

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  • Release Date : 1986
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  • ISBN : 0128044691
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Summary : Read online Molecular Biology of Homo Sapiens written by Marcello Siniscalco,James D. Watson, published by which was released on 1986. Download full Molecular Biology of Homo Sapiens Books now! Available in PDF, ePub and Kindle....

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  • Total pages : 212
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Summary : Read online Annual Review of Genetics written by Herschel L. Roman, published by which was released on 2002. Download full Annual Review of Genetics Books now! Available in PDF, ePub and Kindle....