Non-Enzymatic Protein Modifications in Health, Disease and Ageing
  • Release Date : 15 November 2018
  • Publisher : Academic Press
  • Genre : Uncategorized
  • Pages : 252 pages
  • ISBN 13 : 0128143053
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Download or read book entitled Non-Enzymatic Protein Modifications in Health, Disease and Ageing by author: Izabela Sadowska-Bartosz which was release on 15 November 2018 and published by Academic Press with total page 252 pages . This book available in PDF, EPUB and Kindle Format. There is increased understanding of the fate of intracellular and extracellular proteins, including the many types of posttranslational modifications that proteins undergo. Among these modifications, non-enzymatic protein modifications play a special role. These are unavoidable products of side reactions of reactive metabolites, and often damage proteins and induce loss of function. Non-Enzymatic Protein Modifications in Health, Diseases and Ageing discusses each type of non-enzymatic protein, both introducing non-enzymatic protein modifications, and reviewing the state of the art, presenting updates and current trends. The book covers various aspects of the subject, including formation and removal of modified proteins, their roles in disease, preventative methods, and possible roles in cellular signalling. Finally, the book not only provides well-established facts, but also discusses current hypotheses and controversies. Provides the basic chemical knowledge necessary to understand non-enzymatic protein modifications, of particular use to researchers looking for an introduction to and overview of the field Combines a systematic chemical introduction to non-enzymatic protein modifications with a review of the state of the art Presents together, types of non-enzymatic protein usually reported and reviewed separately Considers current hypotheses and controversies alongside the facts

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