Neurogenic Inflammation in Health and Disease
  • Release Date : 01 December 2021
  • Publisher : Elsevier
  • Genre : Medical
  • Pages : 346 pages
  • ISBN 13 : 9780444532299
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Download or read book entitled Neurogenic Inflammation in Health and Disease by author: Gábor Jancsó which was release on 01 December 2021 and published by Elsevier with total page 346 pages . This book available in PDF, EPUB and Kindle Format. Morphological and functional studies revealed a complex system of primary sensory neurons which parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel which transmits pain. * Neurogenic inflammation in historical perspective * Cardiac protection by nociceptive afferents * Molecular mechanisms of nociception * Sensory mechanisms in migraine pathophysiology * Vagal signalling of visceral inflammation * Neurogenic mechanisms in arthritis * Therapeutic implications of vanilloid-type compounds