Mass Spectrometry for the Clinical Laboratory

Written By Hari Nair
Mass Spectrometry for the Clinical Laboratory
  • Publsiher : Academic Press
  • Release : 02 November 2016
  • ISBN : 0128009926
  • Pages : 304 pages
  • Rating : /5 from reviews
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Download or read book entitled Mass Spectrometry for the Clinical Laboratory by author: Hari Nair which was release on 02 November 2016 and published by Academic Press with total page 304 pages . This book available in PDF, EPUB and Kindle Format. Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, validation of ion suppression/matrix effects, and quality control. These tools offer guidance on what type of instrumentation is optimal for each assay, what options are available, and the pros and cons of each. Readers will find a full set of tools that are either directly related to the assay they want to adopt or for an analogous assay they could use as an example. Written by expert users of the most common assays found in a clinical laboratory (clinical chemists, toxicologists, and clinical pathologists practicing mass spectrometry), the book lays out how experts in the field have chosen their mass spectrometers, purchased, installed, validated, and brought them on line for routine testing. The early chapters of the book covers what the practitioners have learned from years of experience, the challenges they have faced, and their recommendations on how to build and validate assays to avoid problems. These chapters also include recommendations for maintaining continuity of quality in testing. The later parts of the book focuses on specific types of assays (therapeutic drugs, Vitamin D, hormones, etc.). Each chapter in this section has been written by an expert practitioner of an assay that is currently running in his or her clinical lab. Provides readers with the keys to choosing, installing, and validating a mass spectrometry platform Offers tools to evaluate, validate, and troubleshoot the most common assays seen in clinical pathology labs Explains validation, ion suppression, interference testing, and quality control design to the detail that is required for implementation in the lab

Mass Spectrometry for the Clinical Laboratory

Mass Spectrometry for the Clinical Laboratory
  • Author : Hari Nair,William Clarke
  • Publisher : Academic Press
  • Release Date : 2016-11-02
  • Total pages : 304
  • ISBN : 0128009926
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Summary : Mass Spectrometry for the Clinical Laboratory is an accessible guide to mass spectrometry and the development, validation, and implementation of the most common assays seen in clinical labs. It provides readers with practical examples for assay development, and experimental design for validation to meet CLIA requirements, appropriate interference testing, measuring, ...

Principles and Applications of Clinical Mass Spectrometry

Principles and Applications of Clinical Mass Spectrometry
  • Author : Nader Rifai,A. Rita Horvath,Carl T. Wittwer,Andy Hoofnagle
  • Publisher : Elsevier
  • Release Date : 2018-06-26
  • Total pages : 216
  • ISBN : 0128009926
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Summary : Principles and Applications of Clinical Mass Spectrometry: Small Molecules, Peptides, and Pathogens is a concise resource for quick implementation of mass spectrometry methods in clinical laboratory work. Focusing on the practical use of these techniques, the first half of the book covers principles of chromatographic separations, principles and types of ...

Mass spectrometry in the clinical laboratory general principles and guidance approved guideline

Mass spectrometry in the clinical laboratory   general principles and guidance   approved guideline
  • Author : Donald H. Chace
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 97
  • ISBN : 0128009926
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Summary : Read online Mass spectrometry in the clinical laboratory general principles and guidance approved guideline written by Donald H. Chace, published by which was released on 2007. Download full Mass spectrometry in the clinical laboratory general principles and guidance approved guideline Books now! Available in PDF, ePub and Kindle....

Clinical Applications of Mass Spectrometry

Clinical Applications of Mass Spectrometry
  • Author : Uttam Garg,Catherine A. Hammett-Stabler
  • Publisher : Humana
  • Release Date : 2016-08-23
  • Total pages : 538
  • ISBN : 0128009926
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Summary : As mass spectrometric methods now offer a level of specificity and sensitivity unrealized by spectrophotometric- and immunoassay-based methods, mass spectrometry has entered the clinical laboratory where it is being used for a wide range of applications. In Clinical Applications of Mass Spectrometry: Methods and Protocols, expert researchers provide detailed step-by-step ...

Mass Spectrometry An Issue of Clinics in Laboratory Medicine E Book

Mass Spectrometry  An Issue of Clinics in Laboratory Medicine   E Book
  • Author : Nigel Clarke,Andrew N. Hoofnagle
  • Publisher : Elsevier Health Sciences
  • Release Date : 2011-10-03
  • Total pages : 104
  • ISBN : 0128009926
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Summary : This issue of Clinics in Laboratory Medicine, Guest Edited by Nigel Clarke, MD, and Andrew Hoofnagle, MD, will focus on Mass Spectrometry, with topics including: Proteins; Peptides; Small Molecules: Toxicology; Small Molecules: Diagnostics; and Regulatory Considerations....

A Practical Guide to Implementing Clinical Mass Spectrometry Systems

A Practical Guide to Implementing Clinical Mass Spectrometry Systems
  • Author : Neil Leaver
  • Publisher : ILM Publications
  • Release Date : 2011
  • Total pages : 84
  • ISBN : 0128009926
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Summary : Mass spectrometry is becoming increasingly popular in the field of therapeutic drug monitoring. The aim of this publication is to provide practical guidance for laboratories on the implementation of mass spectrometry into a clinical service where there might be limited expertise in the technique. This guidance is the author's personal ...

Medical Applications of Mass Spectrometry

Medical Applications of Mass Spectrometry
  • Author : Karoly Vekey,Andreas Telekes,Akos Vertes
  • Publisher : Elsevier
  • Release Date : 2011-08-11
  • Total pages : 606
  • ISBN : 0128009926
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Summary : Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical ...

Clinical Pathology An Issue of the Clinics in Laboratory Medicine E Book

Clinical Pathology  An Issue of the Clinics in Laboratory Medicine E Book
  • Author : Geza S Bodor
  • Publisher : Elsevier Health Sciences
  • Release Date : 2018-08-19
  • Total pages : 212
  • ISBN : 0128009926
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Summary : This issue of Clinics in Laboratory Medicine will focus on Clinical Pathology and is edited by Geza S. Bodor. Topics include, but are not limited to, Steroid measurement / Salivary cortisol measurement, Protein testing by LCMSMS, LCMSMS in the Clinical Laboratory, Laboratory Standards for Clinical LCMSMS, The need to teach LCMSMS ...

Clinical Applications of Mass Spectrometry in Biomolecular Analysis

Clinical Applications of Mass Spectrometry in Biomolecular Analysis
  • Author : Uttam Garg
  • Publisher : Humana Press
  • Release Date : 2015-11-25
  • Total pages : 333
  • ISBN : 0128009926
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Summary : This volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and no need for specialized reagents. The techniques described are a must for the measurement of ...

Mass Spectrometry in Life Sciences and Clinical Laboratory

Mass Spectrometry in Life Sciences and Clinical Laboratory
  • Author : Goran Mitulović
  • Publisher : BoD – Books on Demand
  • Release Date : 2021-06-02
  • Total pages : 154
  • ISBN : 0128009926
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Summary : Mass spectrometry is a state-of-the-art tool for basic biological research and applied clinical diagnostics. This book covers sample preparation for mass spectrometric analysis for proteomics, clinical studies, and food analysis. In addition, it explores possible directions for further developing the technology and its potential applications....

Toxicology Cases for the Clinical and Forensic Laboratory

Toxicology Cases for the Clinical and Forensic Laboratory
  • Author : Hema Ketha,Uttam Garg
  • Publisher : Academic Press
  • Release Date : 2020-06-20
  • Total pages : 540
  • ISBN : 0128009926
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Summary : Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer ...

Clinical Pathology an Issue of the Clinics in Laboratory Medicine

Clinical Pathology  an Issue of the Clinics in Laboratory Medicine
  • Author : Geza S. Bodor
  • Publisher : Elsevier
  • Release Date : 2018-09-28
  • Total pages : 212
  • ISBN : 0128009926
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Summary : This issue of Clinics in Laboratory Medicine will focus on Clinical Pathology and is edited by Geza S. Bodor. Topics include, but are not limited to, Steroid measurement / Salivary cortisol measurement, Protein testing by LCMSMS, LCMSMS in the Clinical Laboratory, Laboratory Standards for Clinical LCMSMS, The need to teach LCMSMS ...

Beyond LC MS The Next Frontier in Clinical Mass Spectrometry An Issue of the Clinics in Laboratory Medicine E Book

Beyond LC MS  The Next Frontier in Clinical Mass Spectrometry  An Issue of the Clinics in Laboratory Medicine E Book
  • Author : Sankha (Bobby) Basu
  • Publisher : Elsevier Health Sciences
  • Release Date : 2021-05-31
  • Total pages : 240
  • ISBN : 0128009926
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Summary : Beyond LC MS: The Next Frontier in Clinical Mass Spectrometry, An Issue of the Clinics in Laboratory Medicine,E-Book...

Analytical Techniques for Clinical Chemistry

Analytical Techniques for Clinical Chemistry
  • Author : Sergio Caroli,Gyula Záray
  • Publisher : John Wiley & Sons
  • Release Date : 2012-06-26
  • Total pages : 830
  • ISBN : 0128009926
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Summary : Discover how analytical chemistry supports the latest clinical research This book details the role played by analytical chemistry in fostering clinical research. Readers will discover how a broad range of analytical techniques support all phases of clinical research, from early stages to the implementation of practical applications. Moreover, the contributing ...

The Use of Mass Spectrometry Technology MALDI TOF in Clinical Microbiology

The Use of Mass Spectrometry Technology  MALDI TOF  in Clinical Microbiology
  • Author : Fernando Cobo
  • Publisher : Academic Press
  • Release Date : 2018-08-03
  • Total pages : 298
  • ISBN : 0128009926
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Summary : The Use of Mass Spectrometry Technology (MALDI-TOF) in Clinical Microbiology presents the state-of the-art for MALDI-TOF mass spectrometry. It is a key reference defining how MALDI-TOF mass spectrometry is used in clinical settings as a diagnostic tool of microbial identification and characterization that is based on the detection of a ...