Ligand Efficiency Indices for Drug Discovery

Written By Celerino Abad-Zapatero
Ligand Efficiency Indices for Drug Discovery
  • Publsiher : Academic Press
  • Release : 22 January 2013
  • ISBN : 0124046827
  • Pages : 178 pages
  • Rating : /5 from reviews
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Download or read book entitled Ligand Efficiency Indices for Drug Discovery by author: Celerino Abad-Zapatero which was release on 22 January 2013 and published by Academic Press with total page 178 pages . This book available in PDF, EPUB and Kindle Format. The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical methods to drive drug discovery in an encompassing way. These 'new variables' are based on Ligand Efficiency Indices (LEIs) formulated in a way that permits mapping Chemico-Biological Space (CBS) in an Atlas-like representation. It provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery. This book emphasizes the use of a graphical representation and objective numerical methods to drive drug discovery more effectively. It presents the definition of LEIs and the corresponding efficiency planes within an atlas-like environment to provide a robust graphical and numerical framework for medicinal chemists and drug-discoverers. Provides a practical and timely discussion of the concepts, ideas, applications and examples of efficiency-driven drug discovery Emphasizes the use of ‘new variables’ and more objective numerical methods to drive quicker and more effective drug discovery Presents the definition of Ligand Efficiency Indices (LEIs) and the corresponding efficiency planes as key concepts to provide a graphical and numerical framework

Ligand Efficiency Indices for Drug Discovery

Ligand Efficiency Indices for Drug Discovery
  • Author : Celerino Abad-Zapatero
  • Publisher : Academic Press
  • Release Date : 2013-01-22
  • Total pages : 178
  • ISBN : 0124046827
GET BOOK

Summary : The purpose of Ligand Efficiency Indices for Drug Discovery: Towards an Atlas-Guided Paradigm is to introduce in a concise and self-contained form the concepts, ideas, applications and examples of efficiency-driven drug discovery to the biomedical community at large. The book emphasizes the use of 'new variables' and more objective numerical ...

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  • Publisher : Academic Press
  • Release Date : 2018-10-31
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  • ISBN : 0124046827
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Summary : Modern Approaches in Drug Discovery, Volume 611, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Target Identification and Validation, Cell Painting/High Content Imaging, Target ID using chemical probes, Mining the microbiome for ...

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  • ISBN : 0124046827
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Summary : From its origins as a niche technique more than 15 years ago, fragment-based approaches have become a major tool for drug and ligand discovery, often yielding results where other methods have failed. Written by the pioneers in the field, this book provides a comprehensive overview of current methods and applications of ...

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Summary : Presents a different view of medicinal chemistry through personal accounts by eminent scientists describing their lifetime experiences in the field. Also illustrates 14 case studies of successful drug discovery and development. * valuable content available May 2009 as an individual volume * separate volumes will appeal to a wider chemistry, biochemistry and medicinal audience * ...

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Summary : This book guides medicinal chemists in how to implement early ADMET testing in their workflow in order to improve both the speed and efficiency of their efforts. Although many pharmaceutical companies have dedicated groups directly interfacing with drug discovery, the scientific principles and strategies are practiced in a variety of ...

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  • Author : Anonim
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Summary : Read online Australian Journal of Chemistry written by , published by which was released on 2003. Download full Australian Journal of Chemistry Books now! Available in PDF, ePub and Kindle....

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  • Author : Anonim
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Summary : Read online Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great Britain and Ireland and the Council for National Academic Awards written by , published by which was released on 2007. Download full Index to Theses with Abstracts Accepted for Higher Degrees by the Universities of Great ...