Interaction Between a Novel P21 Activated Kinase PAK6 and Androgen Receptor in Prostate Cancer

Written By Anonim
Interaction Between a Novel P21 Activated Kinase  PAK6  and Androgen Receptor in Prostate Cancer
  • Publsiher : Unknown
  • Release : 23 April 2021
  • ISBN :
  • Pages : 24 pages
  • Rating : /5 from reviews
GET THIS BOOKInteraction Between a Novel P21 Activated Kinase PAK6 and Androgen Receptor in Prostate Cancer


Download or read book entitled Interaction Between a Novel P21 Activated Kinase PAK6 and Androgen Receptor in Prostate Cancer by author: Anonim which was release on 23 April 2021 and published by Unknown with total page 24 pages . This book available in PDF, EPUB and Kindle Format. The androgen-signaling pathway is important for the growth and progression of prostate cancer. The cell cycle signaling regulated by the mitogen activated protein/extracellular-signal-regulated kinase (MAPK/ERK) have been linked to tumorigenesis and tumor progression. The p2l-activated kinases (PAKs) are members of a growing class of Rac/Cdc42-associated Ste20-like ser/thr protein kinases. Recent studies have shown that MAPK/ERK signaling can be mediated via Cdc42/Rac-stimulation of PAK activity. Recently, we demonstrated a specific interaction between a novel PAK protein, PAK6, and AR. This finding provided the first link between I PAK-mediated signaling to the steroid hormone receptor pathway. In this study, we propose to assess the biological roles of PAK6 in prostate cancer cells, and to examine the expression of PAK6 in prostate tissues. We anticipate that by completing the objectives proposed in this grant, we will obtain fresh insight into the regulatory processes of AR and PAK6 that may contribute to the development of new targets for the treatment of prostate cancer.

Interaction Between a Novel P21 Activated Kinase PAK6 and Androgen Receptor in Prostate Cancer

Interaction Between a Novel P21 Activated Kinase  PAK6  and Androgen Receptor in Prostate Cancer
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 24
  • ISBN :
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Summary : The androgen-signaling pathway is important for the growth and progression of prostate cancer. The cell cycle signaling regulated by the mitogen activated protein/extracellular-signal-regulated kinase (MAPK/ERK) have been linked to tumorigenesis and tumor progression. The p2l-activated kinases (PAKs) are members of a growing class of Rac/Cdc42-associated ...

Scientific Report

Scientific Report
  • Author : Scripps Research Institute
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 212
  • ISBN :
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Summary : Read online Scientific Report written by Scripps Research Institute, published by which was released on 2003. Download full Scientific Report Books now! Available in PDF, ePub and Kindle....

Endocrine Disruptors

Endocrine Disruptors
  • Author : Rajesh K. Naz
  • Publisher : CRC Press
  • Release Date : 2004-11-29
  • Total pages : 464
  • ISBN :
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Summary : There is great concern regarding the reproductive and health hazards of endocrine disruptors. Research indicates that men are experiencing declining fertility and an increased incidence of prostate cancer, while women are dealing with increased infertility, early menopause, and breast cancer. As new research reveals the previously unknown risks of these ...

Conquering RAS

Conquering RAS
  • Author : Asfar Azmi
  • Publisher : Academic Press
  • Release Date : 2016-08-11
  • Total pages : 294
  • ISBN :
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Summary : Conquering RAS: From Biology to Cancer Therapy provides introductory knowledge on how modern RAS biology is taking shape in light of newer technological development. Each chapter is written in a manner that emphasizes simplicity and readability for both new investigators and established researchers. While RAS biology has been intensively studied ...

Prostate Cancer

Prostate Cancer
  • Author : Leland W. K. Chung,William B. Isaacs,Jonathan W. Simons
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-10
  • Total pages : 508
  • ISBN :
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Summary : Prostate Cancer: Biology, Genetics, and the New Therapeutics, Second Edition, reviews new, valuable approaches to the treatment of prostate cancer in men. The latest edition contains new material on molecular imaging, new treatments for prostate cancer, molecular targets, cell signaling pathways, bioinformatics, and pathogenomics. The book details the latest innovations ...

Experimental Biology and Medicine

Experimental Biology and Medicine
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN :
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Summary : Read online Experimental Biology and Medicine written by , published by which was released on 2008. Download full Experimental Biology and Medicine Books now! Available in PDF, ePub and Kindle....

The Identities of Membrane Steroid Receptors

The Identities of Membrane Steroid Receptors
  • Author : Cheryl S. Watson
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 208
  • ISBN :
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Summary : Cheryl S. Watson University o/Texas Medical Branch Cellular steroid action has been thoroughly studied in the nuclear compartment. However, nuclear steroid receptor mechanisms have been unable to explain some of the rapid activities of steroids, partiCUlarly those which occur in a time frame of seconds to minutes [reviewed in (1;2)]. ...

Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America
  • Author : National Academy of Sciences (U.S.)
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 212
  • ISBN :
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Summary : Read online Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.), published by which was released on 2003. Download full Proceedings of the National Academy of Sciences of the United States of America Books now! Available in PDF, ePub ...

Chemical Abstracts

Chemical Abstracts
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 212
  • ISBN :
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Summary : Read online Chemical Abstracts written by , published by which was released on 2002. Download full Chemical Abstracts Books now! Available in PDF, ePub and Kindle....