Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases

Written By Anil Gupta
Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases
  • Publsiher : Academic Press
  • Release : 15 December 2021
  • ISBN : 9780128201220
  • Pages : 200 pages
  • Rating : /5 from reviews
GET THIS BOOKHuman Caspases and Neuronal Apoptosis in Neurodegenerative Diseases


Download or read book entitled Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases by author: Anil Gupta which was release on 15 December 2021 and published by Academic Press with total page 200 pages . This book available in PDF, EPUB and Kindle Format. Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases discusses neurodegenerative diseases and their epidemiology and clinical presentation, describes the structural organization of human caspases, their classification, role with mitochondria, and mechanisms of activation, including extensive discussions of neuronal apoptosis and its pathways and underlying mechanisms. Finally, the book discusses the intricate mechanisms and interplay between human caspases and neuronal apoptosis in neurodegenerative diseases. All of this is undercut with extensive coverage of molecular events in the pathogenesis of neurodegenerative disorders. Biomedical researchers, graduate students and scientists, along with neuroscientist and student trainees will greatly benefit from this comprehensive information. Neurodegenerative diseases are characterized by progressive structural and/or functional deterioration and eventual death of affected neurons. The progression of these disorders shares similarities at the molecular level. The programmed cell death manifests as blebbing of the plasma membrane, protein degradation, DNA damage and clearance of dead cells by scavengers. Describes the various intricate mechanisms and interplay between human caspases and neuronal apoptosis in neurodegenerative diseases Provides a detailed description of the structural organization and mechanisms of action of various caspases in regulating the process of apoptosis in neurodegenerative diseases Explores the role of various caspases in cell death

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases

Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases
  • Author : Anil Gupta
  • Publisher : Academic Press
  • Release Date : 2021-12-15
  • Total pages : 200
  • ISBN : 9780128201220
GET BOOK

Summary : Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases discusses neurodegenerative diseases and their epidemiology and clinical presentation, describes the structural organization of human caspases, their classification, role with mitochondria, and mechanisms of activation, including extensive discussions of neuronal apoptosis and its pathways and underlying mechanisms. Finally, the book discusses the ...

Targeting the Signalling Cascades Responsible for Human Neuronal Apoptosis Elicited by the Lipid Neuromodulator Platelet Activating Factor

Targeting the Signalling Cascades Responsible for Human Neuronal Apoptosis Elicited by the Lipid Neuromodulator Platelet Activating Factor
  • Author : Tia Corinne Moffat
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 292
  • ISBN : 9780128201220
GET BOOK

Summary : Apoptosis is known to underlie neuronal loss in many human neurodegenerative disorders, such as Alzheimer disease (AD), HIV-dementia and ischemic stroke. Phospholipid signalling is involved in each of these conditions; changes in phospholipid membrane composition and phospholipid synthesis enzyme activity occurs in AD, while in HIV-dementia and ischemia there is ...

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Uday Kishore
  • Publisher : BoD – Books on Demand
  • Release Date : 2013-05-15
  • Total pages : 640
  • ISBN : 9780128201220
GET BOOK

Summary : This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases ...

Role of Proteases in the Pathophysiology of Neurodegenerative Diseases

Role of Proteases in the Pathophysiology of Neurodegenerative Diseases
  • Author : Abel Lajtha,Naren L. Banik
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-05-08
  • Total pages : 302
  • ISBN : 9780128201220
GET BOOK

Summary : Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects for which experimental results are difficult to interpret. The breakdown part of protein turnover in vivo, particularly in nervous tissue, was such a subject in the past – it ...

Neuronal Death by Accident or by Design

Neuronal Death by Accident or by Design
  • Author : C.E. Henderson,D. Green,J. Mariani,Y. Christen
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-14
  • Total pages : 154
  • ISBN : 9780128201220
GET BOOK

Summary : Four chapters represent the intense current effort to understand the way in which the mitochondrion controls the activation of the final stages of cell death. Another four articles attack the problem from the other side. How do specific insults in particular human or mouse neuro-degenerative diseases translate into mechanisms that ...

Pathogenesis of Neurodegenerative Disorders

Pathogenesis of Neurodegenerative Disorders
  • Author : Mark P. Mattson
  • Publisher : Springer Science & Business Media
  • Release Date : 2001-06-01
  • Total pages : 294
  • ISBN : 9780128201220
GET BOOK

Summary : As the average life expectancy of many populations throughout the world increases, so to does the incidence of such age-related neurodegenerative disorders as Alzheimer's, Parkinson's, and Huntington's diseases. Rapid advances in our understanding of the molecular genetics and environmental factors that either cause or increase risk for age-related neurodegenerative disor ...

Neuroinflammation

Neuroinflammation
  • Author : Paul L. Wood
  • Publisher : Springer Science & Business Media
  • Release Date : 2002-12-18
  • Total pages : 420
  • ISBN : 9780128201220
GET BOOK

Summary : In this thoroughly updated and revised edition of his much praised book, Paul L. Wood and a panel of leading researchers capture these new developments in a masterful synthesis of what is known today about the inflammatory mediators and cells involved in neurodegenerative diseases. This second edition contains extensive updates ...

Adenoviral Vector mediated Gene Delivery of Dominant negative Caspase 9 Casp9DN Prevents 6 hydroxydopamine 6 OHDA induced Death of Dopaminergic Neurons in Cell Culture But Not in an Adult Rat Model of Parkinson s Disease

Adenoviral Vector mediated Gene Delivery of Dominant negative Caspase 9  Casp9DN  Prevents 6 hydroxydopamine  6 OHDA  induced Death of Dopaminergic Neurons in Cell Culture  But Not in an Adult Rat Model of Parkinson s Disease
  • Author : Allison Denise Ebert
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 212
  • ISBN : 9780128201220
GET BOOK

Summary : Parkinson's disease (PD) is a neurodegenerative disorder induced by the selective loss of neurons in the brain stem producing the neurotransmitter dopamine (DA). One role for DA is to modulate motor capabilities, and PD is clinically diagnosed by the appearance of various motor disturbances. To date, the cause of sporadic ...

Advances in Research on Neurodegeneration

Advances in Research on Neurodegeneration
  • Author : Y. Mizuno,D.B. Calne,R. Horowski,W. Poewe,P. Riederer,M.B.H. Youdim
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 216
  • ISBN : 9780128201220
GET BOOK

Summary : We organized the Seventh International Winter Conference on Neurodegeneration and Neuroinflammation in a small town of Karuizawa in Nagano Prefecture in Japan on January 20 to 22, 1999. Karuizawa is a nice summer as well as winter resort close to the place for winter Olympic game in the year of 1998. Over 40 scientists gathered ...

Proteases in the Brain

Proteases in the Brain
  • Author : Uwe Lendeckel,Nigel M Hooper
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-01-20
  • Total pages : 384
  • ISBN : 9780128201220
GET BOOK

Summary : In all organs of the body, proteases have critical roles to play both in normal development and functioning and in disease states. The brain is no exception to this, with proteases having emerging roles in synaptic plasticity, memory, neurodegenerative disorders such as Alzheimer’s, Parkinson’s and prion diseases, ischemia ...

Annual Reports in Medicinal Chemistry

Annual Reports in Medicinal Chemistry
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1998
  • Total pages : 212
  • ISBN : 9780128201220
GET BOOK

Summary : Read online Annual Reports in Medicinal Chemistry written by , published by which was released on 1998. Download full Annual Reports in Medicinal Chemistry Books now! Available in PDF, ePub and Kindle....

Use of a Neurotrophic Factor Mimetic to Block Amyloid Toxicity in Alzheimer s Disease Models

Use of a Neurotrophic Factor Mimetic to Block Amyloid Toxicity in Alzheimer s Disease Models
  • Author : Devika Rawal
  • Publisher : Unknown
  • Release Date : 2010
  • Total pages : 58
  • ISBN : 9780128201220
GET BOOK

Summary : Abstract: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the world. The most accepted hypothesis for the cause of this disease is the amyloid cascade hypothesis, which postulates that the formation of extracellular neurotoxic amyloid-beta binds specific receptors on the surface of neuronal and glial cells to increase ...

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Raymond Chuen-Chung Chang
  • Publisher : BoD – Books on Demand
  • Release Date : 2011-12-09
  • Total pages : 572
  • ISBN : 9780128201220
GET BOOK

Summary : Neurodegenerative Diseases - Processes, Prevention, Protection and Monitoring focuses on biological mechanisms, prevention, neuroprotection and even monitoring of disease progression. This book emphasizes the general biological processes of neurodegeneration in different neurodegenerative diseases. Although the primary etiology for different neurodegenerative diseases is different, there is a high level of similarity ...

Proceedings of the Indian National Science Academy

Proceedings of the Indian National Science Academy
  • Author : Indian National Science Academy
  • Publisher : Unknown
  • Release Date : 2004
  • Total pages : 212
  • ISBN : 9780128201220
GET BOOK

Summary : Read online Proceedings of the Indian National Science Academy written by Indian National Science Academy, published by which was released on 2004. Download full Proceedings of the Indian National Science Academy Books now! Available in PDF, ePub and Kindle....

Oxidative Stress and Neurodegenerative Disorders

Oxidative Stress and Neurodegenerative Disorders
  • Author : G. Ali Qureshi,S. Hasan Parvez
  • Publisher : Elsevier
  • Release Date : 2007-03-22
  • Total pages : 794
  • ISBN : 9780128201220
GET BOOK

Summary : Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or ...