Handbook of Pharmacogenomics and Stratified Medicines

Written By Sandosh Padmanabhan
Handbook of Pharmacogenomics and Stratified Medicines
  • Publsiher : Academic Press
  • Release : 06 May 2014
  • ISBN : 9780123868824
  • Pages : 1118 pages
  • Rating : /5 from reviews
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Download or read book entitled Handbook of Pharmacogenomics and Stratified Medicines by author: Sandosh Padmanabhan which was release on 06 May 2014 and published by Academic Press with total page 1118 pages . This book available in PDF, EPUB and Kindle Format. Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be accessible to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by pharmacogenomics and stratified medicine details. Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development. Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics, pharmacokinetics and pharmacodynamics Covers newer technologies- next generation sequencing, proteomics, metabolomics Provides information on animal models, lymphoblastoid cell lines, stem cells Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues Includes chapters on the global implications of pharmacogenomics

Handbook of Pharmacogenomics and Stratified Medicines

Handbook of Pharmacogenomics and Stratified Medicines
  • Author : Sandosh Padmanabhan
  • Publisher : Academic Press
  • Release Date : 2014-05-06
  • Total pages : 1118
  • ISBN : 9780123868824
GET BOOK

Summary : Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic ...

Mastering Pharmacogenomics A Nurse s Handbook for Success

Mastering Pharmacogenomics  A Nurse s Handbook for Success
  • Author : Dale Halsey Lea,Dennis J. Cheek,Daniel Brazeau,Gayle Brazeau
  • Publisher : Sigma Theta Tau
  • Release Date : 2015-01-14
  • Total pages : 264
  • ISBN : 9780123868824
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Summary : Pharmacogenomics, the study of the role of genetics in drug response, has developed into a critical new area in battling disease and improving outcomes. As our knowledge of the human genome grows, and with the advent of next-generation sequencing technologies, the role of genetic research is evolving to guide therapy ...

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Handbook of Personalized Medicine
  • Author : Ioannis S. Vizirianakis
  • Publisher : CRC Press
  • Release Date : 2014-02-12
  • Total pages : 1560
  • ISBN : 9780123868824
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Summary : This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational ...

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  • Author : Kewal K. Jain
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-08-29
  • Total pages : 430
  • ISBN : 9780123868824
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Summary : Personalized medicine, which simply means selection of treatment best suited for an individual, involves integration and translation of several new technologies in clinical care of patients. The scope is much broader than indicated by the term genomic medicine because many non-genomic factors are taken into consideration in developing personalized medicine. ...

Handbook of Biomarkers and Precision Medicine

Handbook of Biomarkers and Precision Medicine
  • Author : Claudio Carini,Mark Fidock,Alain van Gool
  • Publisher : CRC Press
  • Release Date : 2019-04-16
  • Total pages : 631
  • ISBN : 9780123868824
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Summary : "The field of Biomarkers and Precision Medicine in drug development is rapidly evolving and this book presents a snapshot of exciting new approaches. By presenting a wide range of biomarker applications, discussed by knowledgeable and experienced scientists, readers will develop an appreciation of the scope and breadth of biomarker knowledge ...

Handbook of Personalized Medicine

Handbook of Personalized Medicine
  • Author : Ioannis S. Vizirianakis
  • Publisher : CRC Press
  • Release Date : 2014-02-12
  • Total pages : 1560
  • ISBN : 9780123868824
GET BOOK

Summary : This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational ...

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  • Author : Shayne C. Gad
  • Publisher : Wiley-Interscience
  • Release Date : 2007-06-11
  • Total pages : 1659
  • ISBN : 9780123868824
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Summary : Describes the use of biotechnology to develop pharmaceuticals. This book gives the professional a basic tool to facilitate the development of biotech medicines by bringing together a general overview of biotechnology used in the drug development process, along with a compendium of regulations and validation methods....

The Handbook of Biomarkers

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  • Author : Kewal K. Jain
  • Publisher : Humana Press
  • Release Date : 2017-09-16
  • Total pages : 760
  • ISBN : 9780123868824
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Summary : Involved in nearly every therapeutic area, particularly cancer, biomarkers have experienced tremendous advances since the first edition of this book, both in the discovery of biomarkers and in their applications. To aid in this imperative research, Prof. Kewal K. Jain’s Handbook of Biomarkers, Second Edition features a full revision ...

Routledge Handbook of Genomics Health and Society

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  • Author : Sahra Gibbon,Barbara Prainsack,Stephen Hilgartner,Janelle Lamoreaux
  • Publisher : Routledge
  • Release Date : 2018-04-17
  • Total pages : 316
  • ISBN : 9780123868824
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Summary : The Handbook provides an essential resource at the interface of Genomics, Health and Society, and forms a crucial research tool for both new students and established scholars across biomedicine and social sciences. Building from and extending the first Routledge Handbook of Genetics and Society, the book offers a comprehensive introduction ...

Preclinical Development Handbook

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  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release Date : 2008-03-21
  • Total pages : 1080
  • ISBN : 9780123868824
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Summary : A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use ...

Routledge Handbook of Medical Law and Ethics

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  • Author : Yann Joly,Bartha Maria Knoppers
  • Publisher : Routledge
  • Release Date : 2014-09-19
  • Total pages : 480
  • ISBN : 9780123868824
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Summary : This book explores the scope, application and role of medical law, regulatory norms and ethics, and addresses key challenges introduced by contemporary advances in biomedical research and healthcare. While mindful of national developments, the handbook supports a global perspective in its approach to medical law. Contributors include leading scholars in ...

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  • Author : Peter Selby
  • Publisher : EBN Health, an imprint of Evidence-based Networks Ltd
  • Release Date : 2016-11-07
  • Total pages : 256
  • ISBN : 9780123868824
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Summary : Winner of the BMA Oncology Book of the Year Award. This practical learning and reference handbook provides an overview of the latest progress in the developing field of precision oncology, plus a ground breaking collection of case studies ("Problems") showing precision oncology in practice. The book includes a clear, readable ...

Biomarkers in Drug Development

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  • Author : Michael R. Bleavins,Claudio Carini,Mallé Jurima-Romet,Ramin Rahbari
  • Publisher : John Wiley & Sons
  • Release Date : 2011-09-20
  • Total pages : 784
  • ISBN : 9780123868824
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Summary : Discover how biomarkers can boost the success rate of drugdevelopment efforts As pharmaceutical companies struggle to improve the success rateand cost-effectiveness of the drug development process, biomarkershave emerged as a valuable tool. This book synthesizes and reviewsthe latest efforts to identify, develop, and integrate biomarkersas a key strategy in translational ...

Handbook of Basic Pharmacokinetics Including Clinical Applications

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  • Author : Wolfgang A. Ritschel,Gregory L. Kearns,American Pharmaceutical Association
  • Publisher : Amer Pharmacists Assn
  • Release Date : 2004
  • Total pages : 432
  • ISBN : 9780123868824
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Summary : A user-friendly handbook on the principles and techniques involved in the various applications of pharmacokinetics. Provides a concise reference for clinicians who need quick information on the pharmacokinetic characteristics of specific drugs. Thoroughly updated and revised, this book features pharmacokinetic data profiles on more than 600 drugs....

Genetics For Dummies

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  • Author : Tara Rodden Robinson,Lisa Spock
  • Publisher : John Wiley & Sons
  • Release Date : 2020-01-02
  • Total pages : 400
  • ISBN : 9780123868824
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Summary : Your no-nonsense guide to genetics With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify ...