Handbook of Microdialysis

Written By Anonim
Handbook of Microdialysis
  • Publsiher : Elsevier
  • Release : 02 February 2007
  • ISBN : 0080469663
  • Pages : 712 pages
  • Rating : /5 from reviews
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Download or read book entitled Handbook of Microdialysis by author: Anonim which was release on 02 February 2007 and published by Elsevier with total page 712 pages . This book available in PDF, EPUB and Kindle Format. Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to behavior, hormonal and transmitter changes in the nervous system. The book provides a detailed comprehensive overview of the technology and its applications, including application in pathology, drug development, and the application in the clinic. The authors are all well known researchers in Neuroscience and experts in the use of Microdialysis. Organized into two parts of seven sections, the Handbook of Microdialysis critically examines recent developments in the field through a variety of chapters written by an internationally acclaimed group of authors. It is the first comprehensive handbook covering the technology of Microdialysis and its applications in Neuroscience. * Presents microdialysis methods and interpretation including the technical aspects of microdialysis as a sampling technique followed by the analytical chemical methods * Discusses the role of microdialysis in pharmacology, drug development and models of CNS pathology * Includes clinical applications of microdialysis

Handbook of Microdialysis

Handbook of Microdialysis
  • Author : Anonim
  • Publisher : Elsevier
  • Release Date : 2007-02-02
  • Total pages : 712
  • ISBN : 0080469663
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Summary : Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to ...

Microdialysis in the Neurosciences

Microdialysis in the Neurosciences
  • Author : Terry E. Robinson,J. B. Justice
  • Publisher : Elsevier Science Limited
  • Release Date : 1991
  • Total pages : 450
  • ISBN : 0080469663
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Summary : Until very recently most experimental studies on brain chemistry were conducted with postmortem tissue. However, because of shortcomings with postmortem methods and also the desire to directly relate neurochemistry to behavior, there has been a rapid growth of interest towards in vivo neurochemical methods. The recent availability of small diameter ...

Handbook of Non Invasive Methods and the Skin Second Edition

Handbook of Non Invasive Methods and the Skin  Second Edition
  • Author : Jorgen Serup,Gregor B. E. Jemec,Gary L. Grove
  • Publisher : CRC Press
  • Release Date : 2006-02-23
  • Total pages : 1056
  • ISBN : 0080469663
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Summary : Firmly established as the leading international reference in this field, Non-Invasive Methods and the Skin broke new ground with its comprehensive coverage of methods used in both clinical and experimental dermatology. Completely revised and updated, containing more than twice as much information, the Second Edition continues the tradition. The authors' ...

Handbook of Neurochemistry and Molecular Neurobiology

Handbook of Neurochemistry and Molecular Neurobiology
  • Author : Glen Baker,Susan Dunn,Abel Lajtha,Andrew Holt
  • Publisher : Springer Science & Business Media
  • Release Date : 2007
  • Total pages : 485
  • ISBN : 0080469663
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Summary : The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors ...

Microdialysis in Drug Development

Microdialysis in Drug Development
  • Author : Markus M Ller
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-09-11
  • Total pages : 340
  • ISBN : 0080469663
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Summary : In vivo target site concentrations are probably the most important determinant of drug effects. Traditionally, linking drug concentrations to drug effects has been accomplished by modelling blood-derived data, mostly because a direct quantification of tissue concentrations has been beyond technical reach. Today, a direct measurement of target site concentrations is ...

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
  • Author : Michelle A. Rudek,Cindy H. Chau,William D. Figg,Howard L. McLeod
  • Publisher : Springer Science & Business Media
  • Release Date : 2014-01-10
  • Total pages : 836
  • ISBN : 0080469663
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Summary : There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and ...

Handbook of Anxiety and Fear

Handbook of Anxiety and Fear
  • Author : D. Caroline Blanchard,Guy Griebel,David J Nutt
  • Publisher : Elsevier
  • Release Date : 2011-09-02
  • Total pages : 450
  • ISBN : 0080469663
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Summary : This Handbook brings together and integrates comprehensively the core approaches to fear and anxiety. Its four sections: Animal models; neural systems; pharmacology; and clinical approaches, provide a range of perspectives that interact to produce new light on these important and sometimes dysfunctional emotions. Fear and anxiety are analyzed as patterns ...

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
  • Author : William D. Figg,Howard L. McLeod
  • Publisher : Springer Science & Business Media
  • Release Date : 2004-03-26
  • Total pages : 623
  • ISBN : 0080469663
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Summary : Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification of cancer-specific targets to phase III clinical trials. These expert authors provide their best guidance on a wide variety of issues, including clinical ...

Handbook of the Behavioral Neurobiology of Serotonin

Handbook of the Behavioral Neurobiology of Serotonin
  • Author : Christian P. Muller,Barry Jacobs
  • Publisher : Academic Press
  • Release Date : 2009-12-30
  • Total pages : 836
  • ISBN : 0080469663
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Summary : Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic ...

Handbook of Capillary Electrophoresis Second Edition

Handbook of Capillary Electrophoresis  Second Edition
  • Author : James P. Landers
  • Publisher : CRC Press
  • Release Date : 1996-12-23
  • Total pages : 894
  • ISBN : 0080469663
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Summary : Because new information was discovered at an incredible rate since the publication of the successful first edition of this Handbook, this fully updated second edition covers all areas of interest in the field of capillary electrophoresis (CE). A relatively new technology, CE is a principle method for studying the physicochemical ...

Handbook of Solid Phase Microextraction

Handbook of Solid Phase Microextraction
  • Author : Janusz Pawliszyn
  • Publisher : Elsevier
  • Release Date : 2011-11-29
  • Total pages : 496
  • ISBN : 0080469663
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Summary : The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic and drug analysis. This ...

Handbook of Neurosurgery

Handbook of Neurosurgery
  • Author : Mark S. Greenberg
  • Publisher : Thieme
  • Release Date : 2010-02-01
  • Total pages : 1352
  • ISBN : 0080469663
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Summary : A must-have...[a] low-cost, highly portable, and extremely useful reference volume, which will undoubtedly enjoy continued longevity into the foreseeable future.--Journal of NeurosurgeryA vital resource...For rapid access to the diagnosis and management of all neurosurgical things, there is no substitute.--The Journal of TRAUMA Injury, Infection, and Critical ...

Handbook of Neuroendocrinology

Handbook of Neuroendocrinology
  • Author : George Fink,Donald W. Pfaff,Jon E. Levine
  • Publisher : Academic Press
  • Release Date : 2012
  • Total pages : 871
  • ISBN : 0080469663
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Summary : Neuroendocrinology underpins fundamental physiological, molecular, biological, and genetic principles such as the regulation of gene transcription and translation. This handbook highlights the experimental and technical foundations of each area's major concepts and principles....

Biomedical Photonics Handbook

Biomedical Photonics Handbook
  • Author : Tuan Vo-Dinh
  • Publisher : CRC Press
  • Release Date : 2003-03-26
  • Total pages : 1872
  • ISBN : 0080469663
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Summary : A wide variety of biomedical photonic technologies have been developed recently for clinical monitoring of early disease states; molecular diagnostics and imaging of physiological parameters; molecular and genetic biomarkers; and detection of the presence of pathological organisms or biochemical species of clinical importance. However, available information on this rapidly growing ...

Compendium Of In Vivo Monitoring In Real time Molecular Neuroscience Volume 2 Microdialysis And Sensing Of Neural Tissues

Compendium Of In Vivo Monitoring In Real time Molecular Neuroscience   Volume 2  Microdialysis And Sensing Of Neural Tissues
  • Author : George S Wilson,Adrian C Michael
  • Publisher : World Scientific
  • Release Date : 2017-06-28
  • Total pages : 424
  • ISBN : 0080469663
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Summary : Volume 1 of this series focused mainly on small molecules which are intrinsically electroactive. Volume 2 continues to provide current approaches to real time measurements of essential species in the central nervous system. It describes microdialysis, a sampling technique, which facilitates the removal of small volumes of solution containing the analyte(s) ...