From Structure to Clinical Development Allosteric Modulation of G Protein Coupled Receptors

Written By Christopher J. Langmead
From Structure to Clinical Development  Allosteric Modulation of G Protein Coupled Receptors
  • Publsiher : Academic Press
  • Release : 01 June 2020
  • ISBN : 0128201878
  • Pages : 312 pages
  • Rating : /5 from reviews
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Download or read book entitled From Structure to Clinical Development Allosteric Modulation of G Protein Coupled Receptors by author: Christopher J. Langmead which was release on 01 June 2020 and published by Academic Press with total page 312 pages . This book available in PDF, EPUB and Kindle Format. From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP‐1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure‐based discovery and development of mGlu5 NAMs, and much more.

From Structure to Clinical Development Allosteric Modulation of G Protein Coupled Receptors

From Structure to Clinical Development  Allosteric Modulation of G Protein Coupled Receptors
  • Author : Christopher J. Langmead
  • Publisher : Academic Press
  • Release Date : 2020-06
  • Total pages : 312
  • ISBN : 0128201878
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Summary : From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational ...

Multivalent Ligands

Multivalent Ligands
  • Author : Anabel Molero Milan,Universitat de Barcelona. Departament de Química Orgànica
  • Publisher : Unknown
  • Release Date : 2011
  • Total pages : 284
  • ISBN : 0128201878
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Summary : Read online Multivalent Ligands written by Anabel Molero Milan,Universitat de Barcelona. Departament de Química Orgànica, published by which was released on 2011. Download full Multivalent Ligands Books now! Available in PDF, ePub and Kindle....

GPCRs From Deorphanization to Lead Structure Identification

GPCRs  From Deorphanization to Lead Structure Identification
  • Author : H. Bourne,Richard Horuk,J. Kuhnke,H. Michel
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-05-23
  • Total pages : 269
  • ISBN : 0128201878
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Summary : This book offers an insight into the approaches taken by industry and academia to address GPCRs and depict how mature this target class-oriented research has become in the last decade. Coverage also reflects the actual trends in the fast-emerging field of GPCR research in academia and industry. It is based ...

Computational Approaches for Understanding Dynamical Systems Protein Folding and Assembly

Computational Approaches for Understanding Dynamical Systems  Protein Folding and Assembly
  • Author : David B. Teplow
  • Publisher : Academic Press
  • Release Date : 2020-03-04
  • Total pages : 300
  • ISBN : 0128201878
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Summary : Computational Approaches for Understanding Dynamical Systems: Protein Folding and Assembly, Volume 170 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, ...

  • Author : Taylor & Francis Group
  • Publisher : Garland Science
  • Release Date : 2010-12-31
  • Total pages : 212
  • ISBN : 0128201878
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Summary : Read online written by Taylor & Francis Group, published by Garland Science which was released on 2010-12-31. Download full Books now! Available in PDF, ePub and Kindle....

G protein Coupled Receptor GPCR induced Epidermal Growth Factor Receptor EGFR Transactivation

G protein Coupled Receptor  GPCR  induced Epidermal Growth Factor Receptor  EGFR  Transactivation
  • Author : Chintda Santiskulvong
  • Publisher : Unknown
  • Release Date : 2006
  • Total pages : 278
  • ISBN : 0128201878
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Summary : Read online G protein Coupled Receptor GPCR induced Epidermal Growth Factor Receptor EGFR Transactivation written by Chintda Santiskulvong, published by which was released on 2006. Download full G protein Coupled Receptor GPCR induced Epidermal Growth Factor Receptor EGFR Transactivation Books now! Available in PDF, ePub and Kindle....

Neuropeptide GPCRs in neuroendocrinology

Neuropeptide GPCRs in neuroendocrinology
  • Author : Jae Young Seong,Hubert Vaudry
  • Publisher : Frontiers E-books
  • Release Date : 2014-11-07
  • Total pages : 212
  • ISBN : 0128201878
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Summary : The human genome encompasses ˜ 860 G protein-coupled receptors (GPCRs) including 374 non-chemosensory GPCRs. Half of these latter GPCRs recognize (neuro)peptides as natural ligands. GPCRs thus play a pivotal role in neuroendocrine communication. In particular, GPCRs are involved in the neuroendocrine control of feeding behavior, reproduction, growth, hydromineral homeostasis and stress response. ...

Receptors in the Evolution and Development of the Brain

Receptors in the Evolution and Development of the Brain
  • Author : Richard E. Fine, MD
  • Publisher : Academic Press
  • Release Date : 2019-04-15
  • Total pages : 300
  • ISBN : 0128201878
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Summary : Receptors in the Evolution and Development of the Brain: Matter into Mind presents the key role of receptors and their cognate ligands in wiring the mammalian brain from an evolutionary developmental biology perspective. It examines receptor function in the evolution and development of the nervous system in the large vertebrate ...

Modelling of GPCRs

Modelling of GPCRs
  • Author : Andrea Strasser,Hans-Joachim Wittmann
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-08-13
  • Total pages : 218
  • ISBN : 0128201878
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Summary : G protein coupled receptors (GPCRs) comprise an important protein family, which is involved in signal transduction in the cell. Besides that a large number of drugs, available on market, address GPCRs. For an efficient and improved development of appropriate drugs, molecular modelling of GPCRs is – in order to understand the ...

Structure Function Analysis of G Protein Coupled Receptors

Structure Function Analysis of G Protein Coupled Receptors
  • Author : Jürgen Wess
  • Publisher : Wiley-Liss
  • Release Date : 1999-06-15
  • Total pages : 440
  • ISBN : 0128201878
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Summary : G protein-coupled receptors (GPCRs) are the largest single class of receptors in biology, often playing key roles in a remarkably large number of physiological and pathophysiological conditions. GPCRs or GPCR-dependent signalling pathways are the targets of a very large number of therapeutically useful drugs. Detailed knowledge about the molecular structure ...

The G Protein Coupled Receptors Handbook

The G Protein Coupled Receptors Handbook
  • Author : Lakshmi A. Devi
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-03-01
  • Total pages : 412
  • ISBN : 0128201878
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Summary : A comprehensive survey of the many recent advances in the field of G protein-coupled receptors (GPCR). The authors describe the current knowledge of GPCR receptor structure and function, the different mechanisms involved in the regulation of GPCR function, and the role of pharmacological chaperones in GPCR folding and maturation. They ...

Sorting of G Protein coupled Receptors After Endocytosis

Sorting of G Protein coupled Receptors After Endocytosis
  • Author : Patricia I. Tsao
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 150
  • ISBN : 0128201878
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Summary : Read online Sorting of G Protein coupled Receptors After Endocytosis written by Patricia I. Tsao, published by which was released on 2000. Download full Sorting of G Protein coupled Receptors After Endocytosis Books now! Available in PDF, ePub and Kindle....

Nutrient Responsive G Protein Coupled Receptors Mediated and Luminal Dietary Components Initiated Events in the Intestinal Epithelia

Nutrient Responsive G Protein Coupled Receptors Mediated and Luminal Dietary Components Initiated Events in the Intestinal Epithelia
  • Author : Mike Lee
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 438
  • ISBN : 0128201878
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Summary : Read online Nutrient Responsive G Protein Coupled Receptors Mediated and Luminal Dietary Components Initiated Events in the Intestinal Epithelia written by Mike Lee, published by which was released on 2009. Download full Nutrient Responsive G Protein Coupled Receptors Mediated and Luminal Dietary Components Initiated Events in the Intestinal Epithelia Books now! ...

G Protein Coupled Receptors

G Protein Coupled Receptors
  • Author : Sandra Siehler,Graeme Milligan
  • Publisher : Cambridge University Press
  • Release Date : 2010-09-30
  • Total pages : 212
  • ISBN : 0128201878
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Summary : Provides a comprehensive overview of recent discoveries and current understandings of G protein-coupled receptors (GPCRs). Recent advances include the first mammalian non-rhodopsin GPCR structures and reconstitution of purified GPCRs into membrane discs for defined studies, novel signaling features including oligomerization, and advances in understanding the complex ligand pharmacology and physiology ...

G Protein Coupled Receptors

G Protein Coupled Receptors
  • Author : Tatsuya Haga,Shigeki Takeda
  • Publisher : CRC Press
  • Release Date : 2005-08-04
  • Total pages : 336
  • ISBN : 0128201878
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Summary : This book provides a broad base of knowledge of G-protein-coupled receptors. Useful at both the university and industrial levels, this book is of particular interest to those who are developing therapeutic approaches to diseases using drugs that influence receptor activation....