Gene Therapy of Cancer

Written By Edmund C. Lattime
Gene Therapy of Cancer
  • Publsiher : Academic Press
  • Release : 28 August 2013
  • ISBN : 0123946328
  • Pages : 554 pages
  • Rating : /5 from reviews
GET THIS BOOKGene Therapy of Cancer


Download or read book entitled Gene Therapy of Cancer by author: Edmund C. Lattime which was release on 28 August 2013 and published by Academic Press with total page 554 pages . This book available in PDF, EPUB and Kindle Format. Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to the design and testing of new therapeutic approaches. The Third Edition of Gene Therapy of Cancer provides crucial updates on the basic and applied sciences of gene therapy. It offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells. Researchers at all levels of development, from basic laboratory investigators to clinical practitioners, will find this book to be instructive. Cancer gene therapy, like cancer therapy in general, is evolving rapidly, testing new concepts, targets and pathways, evoking new technologies, and passing new regulatory hurdles. Its essence, however, has not changed: the hope and challenges of returning altered genes to normal, using targeted gene expression to alter the function of both tumor and microenvironment, and in some cases normal cells, and delivering functionally important genes to specific cell types to increase sensitivity to killing or to protect normal cells from cancer therapies. In some instances, gene therapy for cancer forms a continuum from gene repair through the use of molecularly modified cells; the use of viral and non-viral vector based gene delivery to both tumor and tumor microenvironment; the use of viral and gene based vaccines; and development of new gene-based therapeutics. The unique mechanistically chosen vector platforms are at the heart of this technology because they allow for direct and selective cell death and transient to sustained delivery of vaccine molecules or molecules that affect the microenvironment, vasculature, or the immune response. Explains the underlying cancer biology necessary for understanding proposed therapeutic approaches Presents in-depth description of targeting systems and treatment strategies Covers the breadth of gene therapy approaches including immunotherapeutic, drug resistance,oncolytic viruses, as well as regulatory perspectives from both the NCI and FDA

Gene Therapy of Cancer

Gene Therapy of Cancer
  • Author : Edmund C. Lattime,Stanton L. Gerson
  • Publisher : Academic Press
  • Release Date : 2013-08-28
  • Total pages : 554
  • ISBN : 0123946328
GET BOOK

Summary : Gene therapy as a treatment for cancer is at a critical point in its evolution. Exciting new developments in gene targeting and vector technology, coupled with results from the first generation of preclinical and clinical studies have led to the design and testing of new therapeutic approaches. The Third Edition ...

Gene Therapy of Cancer

Gene Therapy of Cancer
  • Author : Wolfgang Walther,Ulrike Stein
  • Publisher : Springer Science & Business Media
  • Release Date : 2000
  • Total pages : 645
  • ISBN : 0123946328
GET BOOK

Summary : In Gene Therapy of Cancer: Methods and Protocols, Wolfgang Walther and Ulrike Stein survey the rapidly evolving field cancer gene therapy and provide a broad array of leading-edge protocols for the delivery of therapeutic genes into tumors. Described in step-by-step fashion and enriched with each author's own practical tips, these ...

Gene Therapy of Cancer

Gene Therapy of Cancer
  • Author : Peter Walden,Uwe Trefzer,Wolfram Sterry,Farzin Farzaneh
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 568
  • ISBN : 0123946328
GET BOOK

Summary : The book provides a comprehensive overview of the current state, and the new concepts for the future directions of modern cancer therapy. Bringing together all the relevant aspects from basic and applied science, and the clinical experiences of this new direction in medicine, it is an up-to-date summary of the ...

Gene Therapy in Cancer

Gene Therapy in Cancer
  • Author : Grace W. Redberry
  • Publisher : Nova Publishers
  • Release Date : 2005
  • Total pages : 228
  • ISBN : 0123946328
GET BOOK

Summary : Genes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins. Although genes get a lot of attention, it's the proteins that perform most life functions and even make up the majority ...

Gene Based Therapies for Cancer

Gene Based Therapies for Cancer
  • Author : Jack A. Roth
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-07-28
  • Total pages : 278
  • ISBN : 0123946328
GET BOOK

Summary : Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety ...

Cancer Gene Therapy

Cancer Gene Therapy
  • Author : David T. Curiel,Joanne T. Douglas
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-03
  • Total pages : 490
  • ISBN : 0123946328
GET BOOK

Summary : A complete introduction and guide to the latest developments in cancer gene therapy-from bench to bedside. The authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize ...

Gene Therapy for Cancer

Gene Therapy for Cancer
  • Author : Kelly K. Hunt,Stephan A. Vorburger,Stephen G. Swisher
  • Publisher : Humana Press
  • Release Date : 2007-02-02
  • Total pages : 469
  • ISBN : 0123946328
GET BOOK

Summary : The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment ...

Gene Therapy and Cancer Research Focus

Gene Therapy and Cancer Research Focus
  • Author : Rebecca N. Campbell
  • Publisher : Nova Publishers
  • Release Date : 2008
  • Total pages : 335
  • ISBN : 0123946328
GET BOOK

Summary : Genes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins. Although genes get a lot of attention, it's the proteins that perform most life functions and even make up the majority ...

Gene Therapy of Cancer

Gene Therapy of Cancer
  • Author : Wolfgang Walther,Ulrike Stein
  • Publisher : Humana Press
  • Release Date : 2000-02-17
  • Total pages : 645
  • ISBN : 0123946328
GET BOOK

Summary : Since the discovery of the molecular structure of genes and the unveiling of the molecular basis of numerous human diseases, scientists have been fas- nated with the possibility of treating certain diseases by transducing foreign DNA into the affected cells. Initially, it was proposed that the foreign DNA could either ...

Cancer Gene Therapy by Viral and Non viral Vectors

Cancer Gene Therapy by Viral and Non viral Vectors
  • Author : Malcolm Brenner,Mien-Chie Hung
  • Publisher : John Wiley & Sons
  • Release Date : 2014-02-25
  • Total pages : 176
  • ISBN : 0123946328
GET BOOK

Summary : Provides expert, state-of-the-art insight into the currentprogress of viral and non-viral gene therapy Translational medicine has opened the gateway to the era ofpersonalized or precision medicine. No longer a one-size-fits-allapproach, the treatment of cancer is now based on an understandingof underlying biologic mechanisms and is increasingly beingtailored to the molecular ...

Gene Therapy of Cancer

Gene Therapy of Cancer
  • Author : Stanton L. Gerson,Edmund C. Lattime
  • Publisher : Elsevier
  • Release Date : 2002-04-04
  • Total pages : 534
  • ISBN : 0123946328
GET BOOK

Summary : The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer. The clinical chapters are improved to include new areas of ...

Gene Therapy for Cancer

Gene Therapy for Cancer
  • Author : Kelly K. Hunt,Stephan A. Vorburger,Stephen G. Swisher
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-10-26
  • Total pages : 469
  • ISBN : 0123946328
GET BOOK

Summary : The three sections of this volume present currently available cancer gene therapy techniques. Part I describes the various aspects of gene delivery. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment ...

New Gene Therapy and Cancer Research

New Gene Therapy and Cancer Research
  • Author : Wilma B. Gustafsson
  • Publisher : Nova Publishers
  • Release Date : 2008
  • Total pages : 314
  • ISBN : 0123946328
GET BOOK

Summary : Genes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins. Although genes get a lot of attention, it's the proteins that perform most life functions and even make up the majority ...

Cancer Gene Therapy

Cancer Gene Therapy
  • Author : David T. Curiel,Joanne T. Douglas
  • Publisher : Humana Press
  • Release Date : 2004-09-03
  • Total pages : 490
  • ISBN : 0123946328
GET BOOK

Summary : A complete introduction and guide to the latest developments in cancer gene therapy-from bench to bedside. The authors comprehensively review the anticancer genes and gene delivery methods currently available for cancer gene therapy, including the transfer of genetic material into the cancer cells, stimulation of the immune system to recognize ...

Gene Therapy in the Treatment of Cancer

Gene Therapy in the Treatment of Cancer
  • Author : Brian E. Huber,Ian Magrath
  • Publisher : Cambridge University Press
  • Release Date : 2007-02
  • Total pages : 232
  • ISBN : 0123946328
GET BOOK

Summary : Reviews progress and considers future developments in the fast-evolving field of gene therapy in oncology....