Fibroblast Growth Factors Biology And Clinical Application Fgf Biology And Therapeutics

Written By Simons Michael
Fibroblast Growth Factors  Biology And Clinical Application   Fgf Biology And Therapeutics
  • Publsiher : World Scientific
  • Release : 27 December 2016
  • ISBN : 981314338X
  • Pages : 284 pages
  • Rating : /5 from reviews
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Download or read book entitled Fibroblast Growth Factors Biology And Clinical Application Fgf Biology And Therapeutics by author: Simons Michael which was release on 27 December 2016 and published by World Scientific with total page 284 pages . This book available in PDF, EPUB and Kindle Format. The fibroblast growth factor (FGF) family of ligands and the corresponding family of FGF receptor tyrosine kinases comprise one of the most versatile and diverse growth factor signaling families in vertebrates, found virtually in every tissue and cell type where they regulate metabolic and physiologic function, maintain tissue homeostasis, and mediate injury response, tissue repair, and regeneration. As a result, FGFs play critical roles in a wide variety of normal biological and abnormalities in FGF signaling can lead to a variety of disease states from developmental malformations, to atherosclerosis, pulmonary hypertension and cancer among many others. A thorough understanding of this system is necessary for critical insights into both normal and disease biology and is essential to development of rationale therapeutic strategies aimed at treatment of FGF-dependent diseases states. Recent years have seen advances in our understanding of FGFs role in endothelial and, more general, vascular biology, the subject of this book. In particular, FGFs have been implicated in the maintenance of vascular homeostasis and control of blood vessel permeability while aberrant FGF signaling has been shown to be central to the development of pulmonary hypertension, and endothelial-to-mesenchymal transition, a process implicated in the development of atherosclerosis. Finally, FGFs ability to stimulate blood vessel growth has been explored in therapeutic angiogenesis approaches. With this in mind, the present monograph is structured to provide comprehensive information to a reader interested in FGFs in general and vascular biology in particular. To this end, we explore everything from the structure and signaling of FGFs and their receptors (Chapters 1, 2 and 3) to their role in the regulation of vascular homeostasis (Chapter 4) and cardiovascular diseases (Chapters 5 and 6). We then address new developments in FGF therapeutics (chapter 7) and explore FGF biology in the epithelium (Chapter 8) thereby providing a complete analysis of this growth factor family biology in two closely related but distinctly different environments — endothelium and epithelium. Finally, we examine FGF biology in eye disease and in cancer. It is our hope that this comprehensive treatment of FGF vascular biology and its application will provide the reader with the accurate and timely summary of this rapidly moving field.

Fibroblast Growth Factors Biology And Clinical Application Fgf Biology And Therapeutics

Fibroblast Growth Factors  Biology And Clinical Application   Fgf Biology And Therapeutics
  • Author : Simons Michael
  • Publisher : World Scientific
  • Release Date : 2016-12-27
  • Total pages : 284
  • ISBN : 981314338X
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Summary : The fibroblast growth factor (FGF) family of ligands and the corresponding family of FGF receptor tyrosine kinases comprise one of the most versatile and diverse growth factor signaling families in vertebrates, found virtually in every tissue and cell type where they regulate metabolic and physiologic function, maintain tissue homeostasis, and ...

Fibroblast Growth Factors

Fibroblast Growth Factors
  • Author : Xiaokun Li
  • Publisher : Academic Press
  • Release Date : 2018-06-20
  • Total pages : 576
  • ISBN : 981314338X
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Summary : Fibroblast Growth Factors presents research and results from the leading global research group on FGF, providing up-to-date and comprehensive coverage of the field. The book describes the history, basic research and growth engineering technology involved with FGFs, while also introducing detailed research methods. It comprises eight chapters that detail successes ...

Fibroblast Growth Factor 23

Fibroblast Growth Factor 23
  • Author : Christian Faul,Kenneth White,Orlando Gutierrez
  • Publisher : Elsevier
  • Release Date : 2021-04-06
  • Total pages : 376
  • ISBN : 981314338X
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Summary : Fibroblast Growth Factor 23 describes how FGF23 was initially identified as a bone-derived factor targeting the kidney. As such, sections in this comprehensive book cover exciting research that shows that different FGF23 effects require distinct signaling receptors and mediators that differ among target tissues, cover FGF23 initially identified as a bone-derived ...

Production and Regulation of Acidic and Basic Fibroblast Growth Factors in the Mammary Gland

Production and Regulation of Acidic and Basic Fibroblast Growth Factors in the Mammary Gland
  • Author : Shibani Chakravorti
  • Publisher : Unknown
  • Release Date : 1995
  • Total pages : 430
  • ISBN : 981314338X
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Summary : Read online Production and Regulation of Acidic and Basic Fibroblast Growth Factors in the Mammary Gland written by Shibani Chakravorti, published by which was released on 1995. Download full Production and Regulation of Acidic and Basic Fibroblast Growth Factors in the Mammary Gland Books now! Available in PDF, ePub and Kindle....

Growth Factors and Alzheimer s Disease

Growth Factors and Alzheimer   s Disease
  • Author : Franz Hefti,Philippe Brachet,Bruno Will
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-08
  • Total pages : 244
  • ISBN : 981314338X
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Summary : The study of the relationships between neurotrophic factors (NGF, FGF, amyloid) and neurodegenerative disorders (especially Alzheimer's disease) is of major importance not only for understanding the pathogenesis of the latter, but also for the pharmacological approach to this disease. Information on the subject stemming from the symposium in Strasbourg in ...

Role Fibroblast Growth Factors Bronchi

Role Fibroblast Growth Factors Bronchi
  • Author : WIDYSATUTI
  • Publisher : Unknown
  • Release Date : 2012-06-05
  • Total pages : 212
  • ISBN : 981314338X
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Summary : Read online Role Fibroblast Growth Factors Bronchi written by WIDYSATUTI, published by which was released on 2012-06-05. Download full Role Fibroblast Growth Factors Bronchi Books now! Available in PDF, ePub and Kindle....

Growth Factors

Growth Factors
  • Author : C. Bondy,D. LeRoith
  • Publisher : Elsevier
  • Release Date : 1996-06-25
  • Total pages : 575
  • ISBN : 981314338X
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Summary : This series provides a variety of different discussions on topics within the field of growth factors and cytokines in health and disease....

Roles of Fibroblast Growth Factors FGF During Mammalian Liver Development

Roles of Fibroblast Growth Factors  FGF  During Mammalian Liver Development
  • Author : Joonil Jung
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 412
  • ISBN : 981314338X
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Summary : Read online Roles of Fibroblast Growth Factors FGF During Mammalian Liver Development written by Joonil Jung, published by which was released on 2000. Download full Roles of Fibroblast Growth Factors FGF During Mammalian Liver Development Books now! Available in PDF, ePub and Kindle....

Handbook of Growth Factors

Handbook of Growth Factors
  • Author : Enrique Pimentel
  • Publisher : CRC Press
  • Release Date : 1994-06-02
  • Total pages : 384
  • ISBN : 981314338X
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Summary : Volume II of Handbook of Growth Factors presents a stimulating discussion of the best-characterized polypeptide growth factors, including insulin, insulin-like growth factors, epidermal growth factor, fibroblast growth factors, neurotrophic growth factors, and transforming growth factors. The structure and function of each growth factor is discussed, as well as its receptor ...

Role and Putative Therapeutic Implications of Fibroblast Growth Factor 2 FGF 2 dependent Interplay of Neurotrophic Factors and Signaling Cascades in Amyotrophic Lateral Sclerosis

Role and Putative Therapeutic Implications of Fibroblast Growth Factor 2  FGF 2  dependent Interplay of Neurotrophic Factors and Signaling Cascades in Amyotrophic Lateral Sclerosis
  • Author : Ekaterini Sofia Kefalakes
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 981314338X
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Summary : Read online Role and Putative Therapeutic Implications of Fibroblast Growth Factor 2 FGF 2 dependent Interplay of Neurotrophic Factors and Signaling Cascades in Amyotrophic Lateral Sclerosis written by Ekaterini Sofia Kefalakes, published by which was released on 2018. Download full Role and Putative Therapeutic Implications of Fibroblast Growth Factor 2 FGF 2 dependent Interplay of ...

Defining the Role of Fibroblast Growth Factor Signaling in Vertebrate Limb Development

Defining the Role of Fibroblast Growth Factor Signaling in Vertebrate Limb Development
  • Author : Jamie M. Verheyden
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 135
  • ISBN : 981314338X
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Summary : Read online Defining the Role of Fibroblast Growth Factor Signaling in Vertebrate Limb Development written by Jamie M. Verheyden, published by which was released on 2008. Download full Defining the Role of Fibroblast Growth Factor Signaling in Vertebrate Limb Development Books now! Available in PDF, ePub and Kindle....

Neuronal Growth Factors

Neuronal Growth Factors
  • Author : Mark Bothwell
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-06-29
  • Total pages : 173
  • ISBN : 981314338X
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Summary : A host of environmental factors regulate the embryonic development of neurons. In adults, the survival of neurons, the regeneration of damaged axons, and plastic changes in axonal arborization are also controlled by a complex array of environmental cues. An important category of regulatory influences involves target-derived hormone-like peptides act ing ...

Growth Factors and Wound Healing

Growth Factors and Wound Healing
  • Author : Thomas R. Ziegler,Glenn F. Pierce,David N. Herndon
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 366
  • ISBN : 981314338X
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Summary : The aim of this symposium was to provide basic and clinical investigators with the latest information on the biology of wound healing and tissue repair. Written and edited by eminent experts in the field, the papers cover the general concepts of wound healing; the role of nutrients; endogenous growth factors; ...

Growth Factors

Growth Factors
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1991
  • Total pages : 212
  • ISBN : 981314338X
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Summary : Read online Growth Factors written by , published by which was released on 1991. Download full Growth Factors Books now! Available in PDF, ePub and Kindle....

Growth Factors and Epilepsy

Growth Factors and Epilepsy
  • Author : Helen E. Scharfman
  • Publisher : Nova Publishers
  • Release Date : 2005
  • Total pages : 237
  • ISBN : 981314338X
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Summary : The discovery that a variety of growth factors modulate excitability in the adult brain, and that the expression of growth factors and their receptors are often modulated by seizure activity, has opened an exciting new chapter in epilepsy research. Recent findings shed new light on these and other ways growth ...