Eukaryotic Transcription Factors
  • Release Date : 28 July 2010
  • Publisher : Academic Press
  • Genre : Science
  • Pages : 488 pages
  • ISBN 13 : 0080561039
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Download or read book entitled Eukaryotic Transcription Factors by author: David Latchman which was release on 28 July 2010 and published by Academic Press with total page 488 pages . This book available in PDF, EPUB and Kindle Format. Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. Potential of transcription factors as therapeutic targets in human disease Importance of histone modifications Use of genome-based sequence analysis and high-throughput methods Applications of the chromatin immunoprecipitation (ChIP) assay Transcriptional elongation Regulation by post-translational modifications Regulatory networks and bioinformatics

Transcription Factors

Transcription Factors

Author : Manfred Gossen,Jörg Kaufmann,Steven J. Triezenberg
Publisher : Springer Science & Business Media
Genre : Science
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