Epigenetics Methods

Written By Trygve Tollefsbol
Epigenetics Methods
  • Publsiher : Academic Press
  • Release : 08 July 2020
  • ISBN : 0128194154
  • Pages : 736 pages
  • Rating : /5 from reviews
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Download or read book entitled Epigenetics Methods by author: Trygve Tollefsbol which was release on 08 July 2020 and published by Academic Press with total page 736 pages . This book available in PDF, EPUB and Kindle Format. In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools researchers might employ. Epigenetics Methods offers comprehensive instruction in methods, protocols, and experimental approaches applied in field of epigenetics. Here, across thirty-five chapters, specialists offer step-by-step overviews of methods used to study various epigenetic mechanisms, as employed in basic and translational research. Leading the reader from fundamental to more advanced methods, the book begins with thorough instruction in DNA methylation techniques and gene or locus-specific methylation analyses, followed by histone modification methods, chromatin evaluation, enzyme analyses of histone methylation, and studies of non-coding RNAs as epigenetic modulators. Recently developed techniques and technologies discussed include single-cell epigenomics, epigenetic editing, computational epigenetics, systems biology epigenetic methods, and forensic epigenetic approaches. Epigenetics methods currently in-development, and their implication for future research, are also considered in-depth. In addition, as with the wider life sciences, reproducibility across experiments, labs, and subdisciplines is a growing issue for epigenetics researchers. This volume provides consensus-driven methods instruction and overviews. Tollefsbol and contributing authors survey the range of existing methods; identify best practices, common themes, and challenges; and bring unity of approach to a diverse and ever-evolving field. Includes contributions by leading international investigators involved in epigenetic research and clinical and therapeutic application Integrates technology and translation with fundamental chapters on epigenetics methods, as well as chapters on more novel and advanced epigenetics methods Written at verbal and technical levels that can be understood by scientists and students alike Includes chapters on state-of-the-art techniques such as single-cell epigenomics, use of CRISPR/Cas9 for epigenetic editing, and epigenetics methods applied to forensics

Epigenetics Methods

Epigenetics Methods
  • Author : Trygve Tollefsbol
  • Publisher : Academic Press
  • Release Date : 2020-07-08
  • Total pages : 736
  • ISBN : 0128194154
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Summary : In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools ...

Plant Epigenetics Methods and Protocols

Plant Epigenetics  Methods and Protocols
  • Author : Igor Kovalchuk
  • Publisher : Methods in Molecular Biology
  • Release Date : 2018-11-05
  • Total pages : 264
  • ISBN : 0128194154
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Summary : This volume provides a variety of protocols to analyze various epigenetic changes, including differential expression of non-coding RNAs, changes in DNA methylation, and histone modifications in plants. Chapters detail protocols with different degrees of complexity, and describe bioinformatics approaches for data processing and analysis. Written in the highly successful Methods ...

Cancer Epigenetics

Cancer Epigenetics
  • Author : Ramona G. Dumitrescu,Mukesh Verma
  • Publisher : Humana Press
  • Release Date : 2016-08-23
  • Total pages : 492
  • ISBN : 0128194154
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Summary : The epigenetic regulation plays an important role in normal development and maintenance of tissue specific genes expression in humans and the disturbance of these patterns lead to changes involved in tumor formation. More recently, epigenetic changes have been observed in early stages of tumor development and together with the genetic ...

Epigenetics Protocols

Epigenetics Protocols
  • Author : Trygve O. Tollefsbol
  • Publisher : Springer Science & Business Media
  • Release Date : 2004
  • Total pages : 302
  • ISBN : 0128194154
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Summary : Recent advances in epigenetic research as well as the development of exciting new technologies have helped greatly in unraveling the many mysteries of nontraditional genetic processes. In Epigenetics Protocols, hands-on researchers describe state-of-the-art methods for epigenetic analysis, including recent breakthrough techniques that have great potential in the rapidly expanding field ...

Plant Epigenetics and Epigenomics

Plant Epigenetics and Epigenomics
  • Author : Charles Spillane,Peter McKeown
  • Publisher : Humana
  • Release Date : 2020-02-02
  • Total pages : 272
  • ISBN : 0128194154
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Summary : This second edition volume expands on the previous edition with a look at the latest techniques in plant epigenetics and epigenomic research. Chapters in this book cover topics such as whole genome methylome analysis; analysis of DNA methylation; chromatin analysis of metabolic gene clusters in plants; plant epigenetic stress memory ...

Population Epigenetics

Population Epigenetics
  • Author : Paul Haggarty,Kristina Harrison
  • Publisher : Humana Press
  • Release Date : 2018-07-12
  • Total pages : 206
  • ISBN : 0128194154
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Summary : This detailed volume focuses on population epigenetics, which is of increasing interest to policy makers searching for explanations for complex epidemiological observations and conceptual models on which to base interventions. With a concentration on DNA methylation, the emphasis is on the most commonly studied epigenetic phenomenon that is most amenable ...

Epigenetics of Exercise and Sports

Epigenetics of Exercise and Sports
  • Author : Stuart M Raleigh
  • Publisher : Academic Press
  • Release Date : 2021-01-15
  • Total pages : 400
  • ISBN : 0128194154
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Summary : Exercise and Sports Epigenetics: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence ...

Epigenetic Reprogramming During Mouse Embryogenesis

Epigenetic Reprogramming During Mouse Embryogenesis
  • Author : Katia Ancelin,Maud Borensztein
  • Publisher : Humana
  • Release Date : 2020-10-20
  • Total pages : 318
  • ISBN : 0128194154
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Summary : This volume explores the latest techniques used to study and understand chromatin reprogramming in embryos and germ cells. Various culture systems are presented, which consist of invaluable tools to investigate many developmental processes. This book also looks at methods for direct examination of DNA, RNA, and proteins in embryos, along ...

Developmental Human Behavioral Epigenetics

Developmental Human Behavioral Epigenetics
  • Author : Livio Provenzi,Rosario Montirosso
  • Publisher : Academic Press
  • Release Date : 2020-11-20
  • Total pages : 188
  • ISBN : 0128194154
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Summary : Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics. Featuring contributions from leading scientists and international researchers, this ...

Computational Epigenetics and Diseases

Computational Epigenetics and Diseases
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-02-06
  • Total pages : 450
  • ISBN : 0128194154
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Summary : Computational Epigenetics and Diseases, written by leading scientists in this evolving field, provides a comprehensive and cutting-edge knowledge of computational epigenetics in human diseases. In particular, the major computational tools, databases, and strategies for computational epigenetics analysis, for example, DNA methylation, histone modifications, microRNA, noncoding RNA, and ceRNA, are summarized, ...

Epigenetics of the Immune System

Epigenetics of the Immune System
  • Author : Dieter Kabelitz,Jaydeep Bhat
  • Publisher : Academic Press
  • Release Date : 2020-06-04
  • Total pages : 384
  • ISBN : 0128194154
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Summary : Epigenetics of the Immune System focuses on different aspects of epigenetics and immunology, providing readers with the fundamental mechanisms relating to epigenetics and the immune system. This book provides in-depth information on immune cells as a toolbox in deciphering systematically regulated mechanisms using "omics" and computational biology approaches. In addition, ...

Epigenetics Protocols

Epigenetics Protocols
  • Author : Trygve O. Tollefsbol
  • Publisher : Humana Press
  • Release Date : 2004-07-23
  • Total pages : 304
  • ISBN : 0128194154
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Summary : The field of epigenetics has grown exponentially in the past decade, and a steady flow of exciting discoveries in this area has served to move it to the forefront of molecular biology. Although epigenetics may previously have been considered a peripheral science, recent advances have shown considerable progress in unraveling ...

Epigenetics and Gene Expression in Cancer Inflammatory and Immune Diseases

Epigenetics and Gene Expression in Cancer  Inflammatory and Immune Diseases
  • Author : Barbara Stefanska,David J. MacEwan
  • Publisher : Methods in Pharmacology and To
  • Release Date : 2018-12-28
  • Total pages : 212
  • ISBN : 0128194154
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Summary : This practical collection examines methodologies originating from the benefits of genome-wide approaches to studying epigenetics, which has opened the emerging field of epigenomics. Focusing on the areas of cancer, inflammatory and autoimmune disorders, chapters discuss three main components of the epigenome and their role in the regulation of gene expression ...

Cancer Epigenetics for Precision Medicine

Cancer Epigenetics for Precision Medicine
  • Author : Ramona G. Dumitrescu,Mukesh Verma
  • Publisher : Humana
  • Release Date : 2019-09-17
  • Total pages : 298
  • ISBN : 0128194154
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Summary : This volume discusses certain epigenetic changes recognized in early carcinogenic lesions and different tumors, as well as factors that alter the epigenome and epigenetic profile such as diet, alcohol, immunity, circadian rhythm, and more. The chapters in this book further delve into this field and cover topics such as epigenome-based ...

Twin and Family Studies of Epigenetics

Twin and Family Studies of Epigenetics
  • Author : Shuai Li,John Hopper
  • Publisher : Academic Press
  • Release Date : 2021-10-15
  • Total pages : 408
  • ISBN : 0128194154
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Summary : In recent years, epigenetic modifications have been shown to play an important role in human development and disease progression, and results from ongoing epidemiological studies are already driving advances in medicine and public health. Twin and family studies in epigenetics, by design, offer a unique ability to assess disease risk ...