Epigenetics in Human Disease
  • Release Date : 01 June 2018
  • Publisher : Academic Press
  • Genre : Uncategorized
  • Pages : 704 pages
  • ISBN 13 : 0128122153
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Download or read book entitled Epigenetics in Human Disease by author: Trygve Tollefsbol which was release on 01 June 2018 and published by Academic Press with total page 704 pages . This book available in PDF, EPUB and Kindle Format. Epigenetics is one of the fastest growing fields in biomedical research, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. In Epigenetics in Human Disease, Second Edition, leading international researchers examine those diseases or conditions for which we have advanced knowledge of epigenetic mechanisms such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders, and cardiovascular disease. In addition to detailing the role of epigenetics in the etiology, progression, diagnosis, and prognosis of these diseases, novel epigenetic approaches to treatment are also explored. Fully revised and up-to-date, this new edition discusses topics of current interest in epigenetic research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, online epigenetic tools and data sets, early-life programming of epigenetics in age-related diseases, and epigenetics of addiction and suicide, as well as epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies. With its translational focus, Epigenetics in Human Disease, Second Edition, serves as an invaluable reference for both basic scientists and clinicians alike Includes contributions by leading international investigators involved in translational epigenetic research and therapeutic applications Integrates methods and applications with fundamental chapters on epigenetics in human disease, as well as evaluation of recent epigenetic clinical breakthroughs Side-by-side coverage of the basis of epigenetic diseases and treatment pathways This new edition has been fully revised to cover current developments in disease epigenetics, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, online epigenetic tools and data sets, early-life programming of epigenetics in age-related diseases, and epigenetics of addiction and suicide, as well as epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer's disease, respiratory diseases, and many other human maladies