Drug Repurposing in Cancer Therapy

Written By Kenneth K.W. To
Drug Repurposing in Cancer Therapy
  • Publsiher : Academic Press
  • Release : 29 July 2020
  • ISBN : 0128199032
  • Pages : 458 pages
  • Rating : /5 from reviews
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Download or read book entitled Drug Repurposing in Cancer Therapy by author: Kenneth K.W. To which was release on 29 July 2020 and published by Academic Press with total page 458 pages . This book available in PDF, EPUB and Kindle Format. Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for new repurposing projects. Sections discuss specific topics such as in silico prediction and high throughput screening of repurposed drugs, drug repurposing for overcoming chemoresistance and eradicating cancer stem cells, and clinical investigation on combination of repurposed drug and anticancer therapy. Cancer researchers, oncologists, pharmacologists and several members of biomedical field who are interested in learning more about the use of existing drugs for different purposes in cancer therapy will find this to be a valuable resource. Presents a systematic and up-to-date collection of the research underpinning the various drug repurposing approaches for a quick, but in-depth understanding on current trends in drug repurposing research Brings better understanding of the drug repurposing process in a holistic way, combining both basic and clinical sciences Encompasses a collection of successful stories of drug repurposing for cancer therapy in different cancer types

Drug Repurposing in Cancer Therapy

Drug Repurposing in Cancer Therapy
  • Author : Kenneth K.W. To,William C.S. Cho
  • Publisher : Academic Press
  • Release Date : 2020-07-29
  • Total pages : 458
  • ISBN : 0128199032
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Summary : Drug Repurposing in Cancer Therapy: Approaches and Applications provides comprehensive and updated information from experts in basic science research and clinical practice on how existing drugs can be repurposed for cancer treatment. The book summarizes successful stories that may assist researchers in the field to better design their studies for ...

Multiple Myeloma as an Example of Drug Repurposing for Cancer Treatment

Multiple Myeloma as an Example of Drug Repurposing for Cancer Treatment
  • Author : Charlotte Driessen
  • Publisher : Unknown
  • Release Date : 2020
  • Total pages : 212
  • ISBN : 0128199032
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Summary : Read online Multiple Myeloma as an Example of Drug Repurposing for Cancer Treatment written by Charlotte Driessen, published by which was released on 2020. Download full Multiple Myeloma as an Example of Drug Repurposing for Cancer Treatment Books now! Available in PDF, ePub and Kindle....

pH Interfering Agents as Chemosensitizers in Cancer Therapy

pH Interfering Agents as Chemosensitizers in Cancer Therapy
  • Author : Claudiu Supuran,Simone Carradori
  • Publisher : Academic Press
  • Release Date : 2020-09-15
  • Total pages : 228
  • ISBN : 0128199032
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Summary : pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological applications. The book is structured with innovative outlines and a distinction between experimental and clinical results. ...

An Investigation Into Mechanisms of Action of Colchicine Zinc Acetate and Paracetemol Potential Candidates for Drug Repurposing in Head and Neck Cancer Therapy

An Investigation Into Mechanisms of Action of Colchicine  Zinc Acetate and Paracetemol   Potential Candidates for Drug Repurposing in Head and Neck Cancer Therapy
  • Author : Nadia Shakir
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 54
  • ISBN : 0128199032
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Summary : Read online An Investigation Into Mechanisms of Action of Colchicine Zinc Acetate and Paracetemol Potential Candidates for Drug Repurposing in Head and Neck Cancer Therapy written by Nadia Shakir, published by which was released on 2014. Download full An Investigation Into Mechanisms of Action of Colchicine Zinc Acetate and Paracetemol Potential ...

Drug Repurposing

Drug Repurposing
  • Author : Farid A. Badria
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-12-02
  • Total pages : 234
  • ISBN : 0128199032
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Summary : Drug repurposing or drug repositioning is a new approach to presenting new indications for common commercial and clinically approved existing drugs. For example, chloroquine, an old antimalarial drug, showed promising results for treating COVID-19, interfering with MDR in several types of cancer, and chemosensitizing human leukemic cells.This book focuses ...

Artificial Intelligence in Oncology Drug Discovery and Development

Artificial Intelligence in Oncology Drug Discovery and Development
  • Author : John Cassidy,Belle Taylor
  • Publisher : BoD – Books on Demand
  • Release Date : 2020-09-09
  • Total pages : 192
  • ISBN : 0128199032
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Summary : There exists a profound conflict at the heart of oncology drug development. The efficiency of the drug development process is falling, leading to higher costs per approved drug, at the same time personalised medicine is limiting the target market of each new medicine. Even as the global economic burden of ...

Cracking Cancer Toolkit

Cracking Cancer Toolkit
  • Author : Jeffrey Dach
  • Publisher : Unknown
  • Release Date : 2020-10
  • Total pages : 584
  • ISBN : 0128199032
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Summary : After three family members were stricken with aggressive cancer, I realized I had to get up to speed on the jargon of cancer research, and devise my own cancer toolkit of repurposed drugs and supplements if I wanted my loved ones to survive. This book is a record of that ...

Drug Repurposing in Oncology Tapping Into the Potential of Data Sharing and Partnership Initiatives

Drug Repurposing in Oncology  Tapping Into the Potential of Data Sharing and Partnership Initiatives
  • Author : Isabelle Huys
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 212
  • ISBN : 0128199032
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Summary : Drug repurposing can be broadly defined as finding new uses for existing medicines and in fact covers different development scenarios depending on the product approval status, the patent situation and the required product changes for use in the new indication. A key strategic advantage of drug repurposing over developing new ...

Drug Repurposing and Repositioning

Drug Repurposing and Repositioning
  • Author : Institute of Medicine,Board on Health Sciences Policy,Roundtable on Translating Genomic-Based Research for Health
  • Publisher : National Academies Press
  • Release Date : 2014-08-08
  • Total pages : 118
  • ISBN : 0128199032
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Summary : Drug development can be time-consuming and expensive. Recent estimates suggest that, on average, it takes 10 years and at least $1 billion to bring a drug to market. Given the time and expense of developing drugs de novo, pharmaceutical companies have become increasingly interested in finding new uses for existing drugs - ...

Repurposing Metformin for Lung Cancer Management

Repurposing Metformin for Lung Cancer Management
  • Author : Chuan-Mu Chen
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 212
  • ISBN : 0128199032
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Summary : In this article, we introduced the background knowledge of lung cancer management and considered repurposing old drugs to overcome therapy bottleneck. We chose metformin to prove both its antihyperglycemia and antitumor formation effects. Based on the metformin-related AMPK-dependent pathway, we tried to explore the AMPK-independent pathway in inhibition of lung ...

Drug Repositioning Current Advances and Future Perspectives

Drug Repositioning  Current Advances and Future Perspectives
  • Author : Yuhei Nishimura,Hideaki Hara
  • Publisher : Frontiers Media SA
  • Release Date : 2019-01-11
  • Total pages : 212
  • ISBN : 0128199032
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Summary : Drug repositioning is the process of identifying new indications for existing drugs. At present, the conventional de novo drug discovery process requires an average of about 14 years and US$2.5 billion to approve and launch a drug. Drug repositioning can reduce the time and cost of this process because it takes ...

Drug Repositioning

Drug Repositioning
  • Author : Joel Dudley,Laura Berliocchi
  • Publisher : CRC Press
  • Release Date : 2017-07-14
  • Total pages : 313
  • ISBN : 0128199032
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Summary : Nervous system diseases represent a major health concern worldwide. Although important financial and professional investment, their etiology and pathophysiology still remain mostly elusive. Moreover, the clinical need of disease-modifying therapies is still unmet. In the last decades, traditional R&D has failed in identifying new effective therapies in many medical ...

Drug Diagnostics Co Development in Oncology

Drug Diagnostics Co Development in Oncology
  • Author : Jan Trøst Jørgensen
  • Publisher : Frontiers E-books
  • Release Date : 2014-11-07
  • Total pages : 212
  • ISBN : 0128199032
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Summary : The idea of combining drugs and diagnostics in oncology is not new. When the selective estrogen receptor modulator tamoxifen was developed in the 1970’s for the treatment of breast cancer a positive correlation between receptor status and treatment outcome was found. As a result of this research, it was suggested ...

Drug Repositioning

Drug Repositioning
  • Author : Michael J. Barratt,Donald E. Frail
  • Publisher : John Wiley & Sons
  • Release Date : 2012-05-29
  • Total pages : 477
  • ISBN : 0128199032
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Summary : With Viagra the most famous example, drug repositioning has been growing in importance for pharmaceutical companies seeking to reinvigorate development pipelines. This book provides a broad overview of drug repositioning including the business reasons and unique opportunities and challenges. Its coverage also presents a number of current and emerging technologies ...

In Silico Drug Design

In Silico Drug Design
  • Author : Kunal Roy
  • Publisher : Academic Press
  • Release Date : 2019-02-12
  • Total pages : 886
  • ISBN : 0128199032
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Summary : In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. ...