Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders

Written By Adeboye Adejare
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders
  • Publsiher : Academic Press
  • Release : 20 September 2016
  • ISBN : 0128028114
  • Pages : 316 pages
  • Rating : /5 from reviews
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Download or read book entitled Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders by author: Adeboye Adejare which was release on 20 September 2016 and published by Academic Press with total page 316 pages . This book available in PDF, EPUB and Kindle Format. Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer’s Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer’s Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders. Provides a compilation of chemical considerations required in drug discovery for the treatment of neurodegenerative disorders Examines different classes of compounds currently being used in discovery and development stages Explores in vitro and in vivo models with respect to their ability to translate these models to human conditions Distills the most significant information across multiple areas of Alzheimer’s disease research to provide a single, comprehensive, and balanced resource

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders

Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders
  • Author : Adeboye Adejare
  • Publisher : Academic Press
  • Release Date : 2016-09-20
  • Total pages : 316
  • ISBN : 0128028114
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Summary : Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer’s Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer’s Disease and illustrating the paradigm necessary to ensure future research and treatment success. The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and ...

Remington

Remington
  • Author : Adeboye Adejare
  • Publisher : Academic Press
  • Release Date : 2020-11-03
  • Total pages : 1030
  • ISBN : 0128028114
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Summary : Remington: The Science and Practice of Pharmacy, Twenty Third Edition, offers a trusted, completely updated source of information for education, training, and development of pharmacists. Published for the first time with Elsevier, this edition includes coverage of biologics and biosimilars as uses of those therapeutics have increased substantially since the ...

Principles of Neurochemistry

Principles of Neurochemistry
  • Author : Bijo Mathew,Della Grace Thomas Parambi
  • Publisher : Springer Nature
  • Release Date : 2020-09-21
  • Total pages : 194
  • ISBN : 0128028114
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Summary : This book provides medical professionals and researchers with a comprehensive overview of fundamental concepts and recent advances in neurochemistry, and offers new perspectives for all those involved with research in related disciplines. As drug discovery for neurodegenerative diseases is one of the largest subspecialties in the field of medicine, the ...

Frontiers in Clinical Drug Research Dementia Volume 1

Frontiers in Clinical Drug Research   Dementia  Volume 1
  • Author : Atta-ur-Rahman
  • Publisher : Bentham Science Publishers
  • Release Date : 2020-06-02
  • Total pages : 261
  • ISBN : 0128028114
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Summary : Frontiers in Clinical Drug Research - Dementia is a book series which presents comprehensive reviews about research on Dementia, - the loss of brain function associated with Alzheimer’s disease and other related medical conditions. The disease affects the parts of the brain that deal with memory, thought, and language. ...

Neurobiology of Huntington s Disease

Neurobiology of Huntington   s Disease
  • Author : Donald C. Lo,Robert E. Hughes
  • Publisher : CRC Press
  • Release Date : 2010-07-02
  • Total pages : 338
  • ISBN : 0128028114
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Summary : In 1993, the genetic mutation responsible for Huntington’s disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse range of biochemical and genetic perturbations ...

Drug Repositioning

Drug Repositioning
  • Author : Joel Dudley,Laura Berliocchi
  • Publisher : CRC Press
  • Release Date : 2017-07-14
  • Total pages : 313
  • ISBN : 0128028114
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Summary : Nervous system diseases represent a major health concern worldwide. Although important financial and professional investment, their etiology and pathophysiology still remain mostly elusive. Moreover, the clinical need of disease-modifying therapies is still unmet. In the last decades, traditional R&D has failed in identifying new effective therapies in many medical ...

Frontiers in Clinical Drug Research CNS and Neurological Disorders

Frontiers in Clinical Drug Research   CNS and Neurological Disorders
  • Author : Atta-ur- Rahman
  • Publisher : Bentham Science Publishers
  • Release Date : 2017-12-21
  • Total pages : 290
  • ISBN : 0128028114
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Summary : Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the eBook series covers a range ...

Drug Discovery for Nervous System Diseases

Drug Discovery for Nervous System Diseases
  • Author : Franz Hefti
  • Publisher : Wiley-Liss
  • Release Date : 2005
  • Total pages : 319
  • ISBN : 0128028114
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Summary : The neurosciences have been an especially difficult field for drug discovery. Because of the huge complexity of the nervous system and poor understanding of most psychiatric and neurological diseases, most drugs currently available are the result of chance observations rather than a truly comprehensive approach. However, this situation has begun ...

Therapies for Retinal Degeneration

Therapies for Retinal Degeneration
  • Author : Enrique J de la Rosa,Thomas G Cotter
  • Publisher : Royal Society of Chemistry
  • Release Date : 2018-09-13
  • Total pages : 260
  • ISBN : 0128028114
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Summary : Sight loss and blindness is a very prevalent cause of disability. Retinal diseases leading to visual loss affect many people worldwide and the search for adequate drugs remains a challenge and an important area of interest in the drug discovery field. This book addresses approaches to the treatment of retinal ...

Neurobiology of Huntingtons Disease

Neurobiology of Huntingtons Disease
  • Author : Donald C. Lo,Robert E. Hughes
  • Publisher : CRC Press
  • Release Date : 2017-11-15
  • Total pages : 338
  • ISBN : 0128028114
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Summary : In 1993, the genetic mutation responsible for Huntington�s disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse range of biochemical and genetic perturbations ...

Modern CNS Drug Discovery

Modern CNS Drug Discovery
  • Author : Rudy Schreiber
  • Publisher : Springer
  • Release Date : 2021-07-16
  • Total pages : 283
  • ISBN : 0128028114
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Summary : This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system. It guides the reader through all essential steps, from finding an innovative idea, to the registration of ...

New Scientist

New Scientist
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2001
  • Total pages : 212
  • ISBN : 0128028114
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Summary : Read online New Scientist written by , published by which was released on 2001. Download full New Scientist Books now! Available in PDF, ePub and Kindle....

Brain Behavior and Evolution

Brain  Behavior and Evolution
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1996
  • Total pages : 212
  • ISBN : 0128028114
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Summary : Read online Brain Behavior and Evolution written by , published by which was released on 1996. Download full Brain Behavior and Evolution Books now! Available in PDF, ePub and Kindle....

Structure Based Drug Design for Diagnosis and Treatment of Neurological Diseases

Structure Based Drug Design for Diagnosis and Treatment of Neurological Diseases
  • Author : Rona R. Ramsay,Giuseppe Di Giovanni
  • Publisher : Frontiers Media SA
  • Release Date : 2017-03-24
  • Total pages : 212
  • ISBN : 0128028114
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Summary : European Cooperation in Science and Technology (COST) supports the collaboration of nationally-funded science and technology research through the creation of networks. COST is the longest-running European framework enhancing cooperation among researchers, engineers and scholars across Europe. The COST Action CM1103 “Structure-based drug design for diagnosis and treatment of neurological diseases: ...

Drug Delivery to the Brain

Drug Delivery to the Brain
  • Author : Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lange,Robert G. Thorne
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-12-03
  • Total pages : 731
  • ISBN : 0128028114
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Summary : The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/...