Drug Delivery to the Brain

Written By Margareta Hammarlund-Udenaes
Drug Delivery to the Brain
  • Publsiher : Springer Science & Business Media
  • Release : 03 December 2013
  • ISBN : 1461491053
  • Pages : 731 pages
  • Rating : /5 from reviews
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Download or read book entitled Drug Delivery to the Brain by author: Margareta Hammarlund-Udenaes which was release on 03 December 2013 and published by Springer Science & Business Media with total page 731 pages . This book available in PDF, EPUB and Kindle Format. The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma conditions add further complexity because CNS barriers, drug distribution and pharmacokinetics are dynamic and often changed by disease/trauma. Knowledge of all these factors and their interplay in different conditions is of utmost importance for proper CNS drug development and disease treatment. In recent years much information has become available for a better understanding of the many factors important for CNS drug delivery and how they interact to affect drug action. This book describes small and large drug delivery to the brain with an emphasis on the physiology of the BBB and the principles and concepts for drug delivery across the BBB and distribution within the brain. It contains methods descriptions for studying drug delivery, routes and approaches of administering drugs into the brain, the influence of disease, and drug industry perspectives. Therewith, it contributes to an in-depth understanding of the interplay between brain (patho)-physiology and drug characteristics. Furthermore, the content is designed to be both cutting-edge and educational, so that the book can be used in high-level training of academic and industry scientists with full references to original publications. ​

Nanomedicines for Brain Drug Delivery

Nanomedicines for Brain Drug Delivery
  • Author : Javier O. Morales,Pieter J. Gaillard
  • Publisher : Humana
  • Release Date : 2020-11-20
  • Total pages : 280
  • ISBN : 1461491053
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Summary : This volume explores the latest research in central nervous system (CNS) targeted nanocarriers, methods for their synthesis, and its characterization process. Chapters in this book cover topics such as polymeric nanoparticles and liposomes; self-assembled peptide-based scaffolds for lesions of the nervous system; use of peptides as CNS drugs and as ...

Drug Delivery to the Brain

Drug Delivery to the Brain
  • Author : Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lange,Robert G. Thorne
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-12-03
  • Total pages : 731
  • ISBN : 1461491053
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Summary : The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/...

Peptide Drug Delivery to the Brain

Peptide Drug Delivery to the Brain
  • Author : William M. Pardridge
  • Publisher : Raven Press (ID)
  • Release Date : 1991
  • Total pages : 357
  • ISBN : 1461491053
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Summary : Discusses new and established strategies for delivering peptides and antibodies through the blood-brain barrier. It reviews concepts on blood-brain barrier transport biology, assesses the utility and limitations of traditional brain drug delivery methods and describes new drug delivery techniques....

Drug Delivery to the Brain

Drug Delivery to the Brain
  • Author : Margareta Hammarlund-Udenaes,Elizabeth de Lange,Robert G. Thorne
  • Publisher : Springer
  • Release Date : 2013-12-17
  • Total pages : 731
  • ISBN : 1461491053
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Summary : The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/...

Direct Nose to Brain Drug Delivery

Direct Nose to Brain Drug Delivery
  • Author : Chandrakantsing Pardeshi,Eliana Souto
  • Publisher : Academic Press
  • Release Date : 2021-06-25
  • Total pages : 554
  • ISBN : 1461491053
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Summary : Direct Nose to Brain Drug Delivery: Mechanism, Technological Advances, Applications and Regulatory Updates provides the reader with precise knowledge about the strategies and approaches for enhanced nose to brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with ...

Nanoparticles for Brain Drug Delivery

Nanoparticles for Brain Drug Delivery
  • Author : Carla Vitorino,Andreia Jorge,Alberto A.C.C. Pais
  • Publisher : CRC Press
  • Release Date : 2021-03-16
  • Total pages : 504
  • ISBN : 1461491053
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Summary : In an era wherein nanotechnology has sparked a huge research interest, brain drug delivery is not an exception. Aiming at fighting several central nervous system (CNS) conditions, tailored nanoparticles open new avenues to address several challenges in the fields of drug delivery and brain targeting. This book gathers contributions from ...

Nanocarriers for Brain Targeting

Nanocarriers for Brain Targeting
  • Author : Raj K. Keservani,Anil K. Sharma,Rajesh K. Kesharwani
  • Publisher : CRC Press
  • Release Date : 2019-08-27
  • Total pages : 512
  • ISBN : 1461491053
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Summary : This new volume, Nanocarriers for Brain Targeting: Principles and Applications, covers recent research on brain physiology and the development of drug delivery systems. It explores a diverse variety of strategies that can be employed to achieve drug targeting to the brain. The nanocarriers that are discussed include nanoparticles, vesicular carriers, ...

Peptide Drug Delivery to the Brain

Peptide Drug Delivery to the Brain
  • Author : William M. Pardridge
  • Publisher : Unknown
  • Release Date : 1991-01-01
  • Total pages : 367
  • ISBN : 1461491053
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Summary : Read online Peptide Drug Delivery to the Brain written by William M. Pardridge, published by which was released on 1991-01-01. Download full Peptide Drug Delivery to the Brain Books now! Available in PDF, ePub and Kindle....

Blood Brain Barrier

Blood Brain Barrier
  • Author : David Kobiler,Shlomo Lustig,Shlomo Shapira
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Total pages : 434
  • ISBN : 1461491053
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Summary : The vasculature of the central nervous system (eNS) is characterized by the existence of the blood-brain barrier (BBB), which can be regarded as both an anatomical and physiological phenomenon. The BBB is formed by a complex cellular system of endothelial cells, astroglia, pericytes, perivascular macrophages and a basal membrane, although ...

Nanotechnology Methods for Neurological Diseases and Brain Tumors

Nanotechnology Methods for Neurological Diseases and Brain Tumors
  • Author : Yasemin Gürsoy Özdemir,Sibel Bozdag Pehlivan,Emine Sekerdag
  • Publisher : Academic Press
  • Release Date : 2017-07-14
  • Total pages : 378
  • ISBN : 1461491053
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Summary : Nanotechnology Methods for Neurological Diseases and Brain Tumors: Drug Delivery across the Blood-Brain Barrier compiles the latest (and future potential) treatment strategies for brain tumors and neurological diseases, in particular Alzheimer’s, Parkinson’s and stroke, those that bypass the blood/brain barrier. The current understanding of brain drug delivery ...

Nanotechnology Based Targeted Drug Delivery Systems for Brain Tumors

Nanotechnology Based Targeted Drug Delivery Systems for Brain Tumors
  • Author : Prashant Kesharwani,Umesh Gupta
  • Publisher : Academic Press
  • Release Date : 2018-04-20
  • Total pages : 478
  • ISBN : 1461491053
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Summary : Nanotechnology-Based Targeted Drug Delivery Systems for Brain Tumors addresses brain anatomy and tumors and the progress and challenges in delivering drugs across the blood brain barrier. Several chapters are devoted to the latest technologies and advances in nanotechnology, along with practical solutions on how to design more effective nanocarriers for ...

Direct Nose to Brain Drug Delivery

Direct Nose to Brain Drug Delivery
  • Author : Chandrakantsing Pardeshi,Eliana Souto
  • Publisher : Elsevier
  • Release Date : 2021-07-09
  • Total pages : 554
  • ISBN : 1461491053
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Summary : Direct Nose to Brain Drug Delivery: Mechanism, Technological Advances, Applications and Regulatory Updates provides the reader with precise knowledge about the strategies and approaches for enhanced nose to brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with ...

Special Issue Targeted Drug Delivery to the Brain

Special Issue  Targeted Drug Delivery to the Brain
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 212
  • ISBN : 1461491053
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Summary : Read online Special Issue Targeted Drug Delivery to the Brain written by , published by which was released on 2000. Download full Special Issue Targeted Drug Delivery to the Brain Books now! Available in PDF, ePub and Kindle....

Drug Delivery Through the Blood Brain Barrier

Drug Delivery Through the Blood Brain Barrier
  • Author : William M. Pardridge
  • Publisher : Unknown
  • Release Date : 1995
  • Total pages : 180
  • ISBN : 1461491053
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Summary : Read online Drug Delivery Through the Blood Brain Barrier written by William M. Pardridge, published by which was released on 1995. Download full Drug Delivery Through the Blood Brain Barrier Books now! Available in PDF, ePub and Kindle....

Blood Brain Barrier in Drug Discovery

Blood Brain Barrier in Drug Discovery
  • Author : Li Di,Edward H. Kerns
  • Publisher : John Wiley & Sons
  • Release Date : 2015-02-02
  • Total pages : 600
  • ISBN : 1461491053
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Summary : Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – areas of drug discovery. • Written by world experts to provide practical solutions to increase brain penetration ...