Drug Biomembrane Interaction Studies

Written By Rosario Pignatello
Drug Biomembrane Interaction Studies
  • Publsiher : Elsevier
  • Release : 31 October 2013
  • ISBN : 1908818344
  • Pages : 440 pages
  • Rating : /5 from reviews
GET THIS BOOKDrug Biomembrane Interaction Studies


Download or read book entitled Drug Biomembrane Interaction Studies by author: Rosario Pignatello which was release on 31 October 2013 and published by Elsevier with total page 440 pages . This book available in PDF, EPUB and Kindle Format. The design and development of drugs and new pharmaceutical formulations require a full characterization of the chemical and physicochemical events occurring at the level of the single active ingredients or excipients, as well as their reciprocal interaction. Thermal analysis techniques are among the most widely used methods to achieve this; among them, the Differential Scanning Calorimetry (DSC) technique, in which the thermotropic behaviour of a single substance or mixtures is analyzed as a function of a controlled temperature program. DSC is an accurate and rapid thermo-analytical technique, widely used by the pharmaceutical industry and in drug research to investigate several physico-chemical phenomena, such as polymorphism, melting and crystallization, purity, and drug-excipient interaction; as well as characterizing biomolecules such as genetic material. Drug-biomembrane interaction studies is written by scientists renowned for their work in the field of DSC applications to drug development and delivery, and especially to drug-biomembrane interaction studies. The book combines insights from biochemistry and physiology with those from structural biology, nanotechnology and biothermodynamics, to obtain a complete depiction of cell membranes and their functions. Summarizes and updates the recent development in a unique handbook format Consists of a combination of scientific updates within the field Contains chapters written by some of the highest-level experts in the field of DSC

Drug Biomembrane Interaction Studies

Drug Biomembrane Interaction Studies
  • Author : Rosario Pignatello
  • Publisher : Elsevier
  • Release Date : 2013-10-31
  • Total pages : 440
  • ISBN : 1908818344
GET BOOK

Summary : The design and development of drugs and new pharmaceutical formulations require a full characterization of the chemical and physicochemical events occurring at the level of the single active ingredients or excipients, as well as their reciprocal interaction. Thermal analysis techniques are among the most widely used methods to achieve this; ...

Drug biomembrane interaction studies

Drug   biomembrane interaction studies
  • Author : A. Fortunato
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-10-31
  • Total pages : 440
  • ISBN : 1908818344
GET BOOK

Summary : In DSC, the heat flow in and out of a sample and a reference material is measured as a function of temperature as the sample is heated, cooled, or held isothermally at constant temperature. The measurement signal is the energy absorbed or released by the sample in milliwatts. DSC can ...

Drug biomembrane interaction studies

Drug   biomembrane interaction studies
  • Author : M.H. Chiu,N.S. Berezowski,E.J. Prenner
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-10-31
  • Total pages : 440
  • ISBN : 1908818344
GET BOOK

Summary : DSC is a straightforward, non-perturbing thermodynamic technique first developed in the early 1960s. The large number of parameters and the high sensitivity has made DSC one of the key calorimetric tools used for investigating thermodynamic properties of biopolymers, proteins, peptides and nucleic acids. There are numerous reviews covering the different ...

Drug biomembrane interaction studies

Drug   biomembrane interaction studies
  • Author : C. Carbone,R. Pignatello
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-10-31
  • Total pages : 440
  • ISBN : 1908818344
GET BOOK

Summary : Interest in using DSC to study the interaction between different compounds and biomembrane models has increased in the last 20years. This is confirmed by the number of published research studies concerning the feasibility of investigating the behavior of different molecules, such as local anesthetics, anticancer drugs, anti-inflammatory drugs, antioxidants, antibiotics, ...

Drug biomembrane interaction studies

Drug   biomembrane interaction studies
  • Author : R. Pignatello
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-10-31
  • Total pages : 440
  • ISBN : 1908818344
GET BOOK

Summary : DSC studies of the interaction between drugs or other biologically active compounds with biomembrane models has often been associated or integrated with other analytical methodologies. The information gained from various techniques can depict the different and complex elements that compose such interactions. This chapter will summarize some recent examples of ...

Drug biomembrane interaction studies

Drug   biomembrane interaction studies
  • Author : T. Musumeci,G. Puglisi
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-10-31
  • Total pages : 440
  • ISBN : 1908818344
GET BOOK

Summary : Antimicrobial agents are from different classes of molecules that suppress multiplication and growth of or kill microorganisms such as bacteria, fungi, or viruses. The precise mechanism of action of some antimicrobial agents is unknown but they must interact with or cross the cell membrane to have an effect. Identification of ...

Indian Science Abstracts

Indian Science Abstracts
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1994
  • Total pages : 212
  • ISBN : 1908818344
GET BOOK

Summary : Read online Indian Science Abstracts written by , published by which was released on 1994. Download full Indian Science Abstracts Books now! Available in PDF, ePub and Kindle....

Methods in Membrane Lipids

Methods in Membrane Lipids
  • Author : Alex Dopico
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-08-30
  • Total pages : 621
  • ISBN : 1908818344
GET BOOK

Summary : This book presents a compendium of methodologies for the study of membrane lipids, varying from traditional lab bench experimentation to computer simulation and theoretical models. The volume provides a comprehensive set of techniques for studying membrane lipids with a strong biophysical emphasis. It compares the various available techniques including the ...

Thermal Analysis in Research and Industry

Thermal Analysis in Research and Industry
  • Author : Indra K. Varma,A. C. Momin
  • Publisher : Unknown
  • Release Date : 1989
  • Total pages : 424
  • ISBN : 1908818344
GET BOOK

Summary : Read online Thermal Analysis in Research and Industry written by Indra K. Varma,A. C. Momin, published by which was released on 1989. Download full Thermal Analysis in Research and Industry Books now! Available in PDF, ePub and Kindle....

Progress and Trends in Applied Optical Spectroscopy

Progress and Trends in Applied Optical Spectroscopy
  • Author : Dieter Fassler
  • Publisher : B. G. Teubner Gmbh
  • Release Date : 1987
  • Total pages : 291
  • ISBN : 1908818344
GET BOOK

Summary : Read online Progress and Trends in Applied Optical Spectroscopy written by Dieter Fassler, published by B. G. Teubner Gmbh which was released on 1987. Download full Progress and Trends in Applied Optical Spectroscopy Books now! Available in PDF, ePub and Kindle....

QSAR and Molecular Modeling Studies in Heterocyclic Drugs I

QSAR and Molecular Modeling Studies in Heterocyclic Drugs I
  • Author : S.P. Gupta
  • Publisher : Springer Verlag
  • Release Date : 2006-06-22
  • Total pages : 278
  • ISBN : 1908818344
GET BOOK

Summary : Read online QSAR and Molecular Modeling Studies in Heterocyclic Drugs I written by S.P. Gupta, published by Springer Verlag which was released on 2006-06-22. Download full QSAR and Molecular Modeling Studies in Heterocyclic Drugs I Books now! Available in PDF, ePub and Kindle....

CA Reviews Index CARI

CA Reviews Index  CARI
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1982
  • Total pages : 212
  • ISBN : 1908818344
GET BOOK

Summary : Read online CA Reviews Index CARI written by , published by which was released on 1982. Download full CA Reviews Index CARI Books now! Available in PDF, ePub and Kindle....

Membrane Mechanisms of Drugs of Abuse

Membrane Mechanisms of Drugs of Abuse
  • Author : Charles William Sharp,Leo G. Abood
  • Publisher : Unknown
  • Release Date : 1979
  • Total pages : 272
  • ISBN : 1908818344
GET BOOK

Summary : Read online Membrane Mechanisms of Drugs of Abuse written by Charles William Sharp,Leo G. Abood, published by which was released on 1979. Download full Membrane Mechanisms of Drugs of Abuse Books now! Available in PDF, ePub and Kindle....

The Annual Guides to Graduate Study

The Annual Guides to Graduate Study
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1974
  • Total pages : 212
  • ISBN : 1908818344
GET BOOK

Summary : Read online The Annual Guides to Graduate Study written by , published by which was released on 1974. Download full The Annual Guides to Graduate Study Books now! Available in PDF, ePub and Kindle....

Survey of Drug Research in Immunologic Disease

Survey of Drug Research in Immunologic Disease
  • Author : Vassil St Georgiev
  • Publisher : Unknown
  • Release Date : 1983
  • Total pages : 542
  • ISBN : 1908818344
GET BOOK

Summary : Read online Survey of Drug Research in Immunologic Disease written by Vassil St Georgiev, published by which was released on 1983. Download full Survey of Drug Research in Immunologic Disease Books now! Available in PDF, ePub and Kindle....