Direct Nose to Brain Drug Delivery

Written By Chandrakantsing Pardeshi
Direct Nose to Brain Drug Delivery
  • Publsiher : Academic Press
  • Release : 25 June 2021
  • ISBN : 0128225238
  • Pages : 554 pages
  • Rating : /5 from reviews
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Download or read book entitled Direct Nose to Brain Drug Delivery by author: Chandrakantsing Pardeshi which was release on 25 June 2021 and published by Academic Press with total page 554 pages . This book available in PDF, EPUB and Kindle Format. Direct Nose to Brain Drug Delivery: Mechanism, Technological Advances, Applications and Regulatory Updates provides the reader with precise knowledge about the strategies and approaches for enhanced nose to brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with a focus on the technological advances in the development of the novel drug delivery devices for intranasal administration, including special emphasis on brain targeting through nose. This book explores the various quantification parameters to assess the brain targeting efficiency following intranasal administration, includes an overview on the toxicity aspects of the various materials used to develop the direct nose to brain drug delivery vehicles and of the regulatory aspects including patents and current clinical status of the potential neurotherapeutics for the effective management of neuro-ailments. Technological advances in new drug delivery systems with diverse applications in pharmaceutical, biomedical, biomaterials, and biotechnological fields are also explained. Direct Nose to Brain Drug Delivery: Mechanism, Technological Advances, Applications and Regulatory Updates is a crucial source that will assist the veteran scientists, industrial technologists, and clinical research professionals to develop new drug delivery systems, and novel drug administration devices for the treatment of neuro-ailments. Explains the targeting approaches for enhanced brain targeting following intranasal drug administration Explores the various nanocarriers developed to date for neurotherapeutic delivery via nose to brain Discusses pharmaceutical and biomedical applications after nose to brain delivery of therapeutic pharmaceuticals and biologicals

Direct Nose to Brain Drug Delivery

Direct Nose to Brain Drug Delivery
  • Author : Chandrakantsing Pardeshi,Eliana Souto
  • Publisher : Academic Press
  • Release Date : 2021-06-25
  • Total pages : 554
  • ISBN : 0128225238
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Summary : Direct Nose to Brain Drug Delivery: Mechanism, Technological Advances, Applications and Regulatory Updates provides the reader with precise knowledge about the strategies and approaches for enhanced nose to brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with ...

Direct Nose to Brain Drug Delivery

Direct Nose to Brain Drug Delivery
  • Author : Chandrakantsing Pardeshi,Eliana Souto
  • Publisher : Elsevier
  • Release Date : 2021-07-09
  • Total pages : 554
  • ISBN : 0128225238
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Summary : Direct Nose to Brain Drug Delivery: Mechanism, Technological Advances, Applications and Regulatory Updates provides the reader with precise knowledge about the strategies and approaches for enhanced nose to brain drug delivery. It highlights the development of novel nanocarrier-based drug delivery systems for targeted drug delivery to the brain microenvironments with ...

The Development and Applications of Biological Models for Evaluation of Direct Nose to brain Drug Delivery Systems

The Development and Applications of Biological Models for Evaluation of Direct Nose to brain Drug Delivery Systems
  • Author : Alpesh Mistry
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 526
  • ISBN : 0128225238
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Summary : Read online The Development and Applications of Biological Models for Evaluation of Direct Nose to brain Drug Delivery Systems written by Alpesh Mistry, published by which was released on 2009. Download full The Development and Applications of Biological Models for Evaluation of Direct Nose to brain Drug Delivery Systems Books now! ...

The Impact of Enhanced Olfactory Deposition and Retention on Direct Nose to brain Drug Delivery

The Impact of Enhanced Olfactory Deposition and Retention on Direct Nose to brain Drug Delivery
  • Author : John D. Hoekman
  • Publisher : Unknown
  • Release Date : 2010
  • Total pages : 324
  • ISBN : 0128225238
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Summary : Read online The Impact of Enhanced Olfactory Deposition and Retention on Direct Nose to brain Drug Delivery written by John D. Hoekman, published by which was released on 2010. Download full The Impact of Enhanced Olfactory Deposition and Retention on Direct Nose to brain Drug Delivery Books now! Available in PDF, ...

The Development and Application of Biological Models for Evaluation of Direct Nose to brain Drug Delivery Systems

The Development and Application of Biological Models for Evaluation of Direct Nose to brain Drug Delivery Systems
  • Author : Alpesh Mistry
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 263
  • ISBN : 0128225238
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Summary : The olfactory neuroepithelium is the only part of the central nervous system that is exposed directly to the external environment. Therefore, it is the only non-invasive drug delivery route to the brain. Surface modification of PS nanoparticles with chitosan (C-PS), polysorbate 80 (P80-PS) and polysorbate 80+FCS (P80-FCS-PS) changed the ...

Nasal Drug Delivery

Nasal Drug Delivery
  • Author : Mascha van den Berg
  • Publisher : Unknown
  • Release Date : 2005
  • Total pages : 203
  • ISBN : 0128225238
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Summary : With the growing number of patients suffering from central nervous system (CNS) diseases a suitable approach for drug targeting to the brain becomes more and more important. This is a major problem in drug delivery research, due to the tight blood-brain barrier (BBB) that prevents the influx of xenobiotic compounds ...

Numerical Simulation and Experimental Testing to Improve Olfactory Drug Delivery with Electric Field Guidance of Charged Particles

Numerical Simulation and Experimental Testing to Improve Olfactory Drug Delivery with Electric Field Guidance of Charged Particles
  • Author : Jinxiang Xi
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 212
  • ISBN : 0128225238
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Summary : Even though the direct nose-to-brain drug delivery has many clinical benefits, there are limited successes in delivering medication aerosols to the olfactory mucosa with standard inhalation devices. In this study, different delivery techniques were assessed in terms of their capacities to deliver drug aerosols to the olfactory epithelium. Specifically, the ...

Drug Delivery Systems

Drug Delivery Systems
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-10-23
  • Total pages : 792
  • ISBN : 0128225238
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Summary : Drug Delivery Systems examines the current state of the field within pharmaceutical science and concisely explains the history of drug delivery systems, including key developments. The book translates the physicochemical properties of drugs into drug delivery systems administered via various routes, such as oral, parenteral, transdermal and inhalational. Regulatory and ...

Drug Delivery to the Brain

Drug Delivery to the Brain
  • Author : Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lange,Robert G. Thorne
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-12-03
  • Total pages : 731
  • ISBN : 0128225238
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Summary : The development of new CNS drugs is notoriously difficult. Drugs must reach CNS target sites for action and these sites are protected by a number of barriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/...

Drug Transporters in the Nasal Epithelia and Their Contribution in Drug Delivery

Drug Transporters in the Nasal Epithelia and Their Contribution in Drug Delivery
  • Author : Manar I. Al-Ghabeish
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 168
  • ISBN : 0128225238
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Summary : The nasal route has primarily been used to deliver drugs for the treatment of local diseases such as nasal infections, nasal congestion and allergies. The nasal route can also be used as a non-invasive alternative route to deliver drugs systemically when a rapid onset of action and/or avoidance of ...

Theory and Applications of Nonparenteral Nanomedicines

Theory and Applications of Nonparenteral Nanomedicines
  • Author : Prashant Kesharwani,Sebastien Taurin,Khaled Greish
  • Publisher : Academic Press
  • Release Date : 2020-09-12
  • Total pages : 540
  • ISBN : 0128225238
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Summary : Theory and Applications of Nonparenteral Nanomedicines presents thoroughly analysed data and results regarding the potential of nanomedicines conceived by diverse non-parenteral routes. In the context of nanotechnology-based approaches, various routes such as oral, pulmonary, transdermal, delivery and local administration of nanomedicine have been utilized for the delivery of nanomedicine. This ...

Brain Targeted Drug Delivery Systems

Brain Targeted Drug Delivery Systems
  • Author : Huile Gao,Xiaoling Gao
  • Publisher : Academic Press
  • Release Date : 2018-09-20
  • Total pages : 499
  • ISBN : 0128225238
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Summary : Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on ...

Nanobiotechnology in Neurodegenerative Diseases

Nanobiotechnology in Neurodegenerative Diseases
  • Author : Mahendra Rai,Alka Yadav
  • Publisher : Springer Nature
  • Release Date : 2019-12-02
  • Total pages : 398
  • ISBN : 0128225238
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Summary : This book focuses on neurodegenerative diseases which have become a major threat to human health. Neurodegenerative diseases are age related disorders and have become increasingly prevalent in the elderly population in recent years. Hence, there is an urgent need to study and develop new strategies and alternative methods for the ...

Nanomaterials for Drug Delivery and Therapy

Nanomaterials for Drug Delivery and Therapy
  • Author : Alexandru Mihai Grumezescu
  • Publisher : William Andrew
  • Release Date : 2019-03-14
  • Total pages : 580
  • ISBN : 0128225238
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Summary : Nanomaterials for Drug Delivery and Therapy presents recent advances in the field of nanobiomaterials and their important applications in drug delivery, therapy and engineering. The book offers pharmaceutical perspectives, exploring the development of nanobiomaterials and their interaction with the human body. Chapters show how nanomaterials are used in treatments, including ...

Bioadhesives in Drug Delivery

Bioadhesives in Drug Delivery
  • Author : K. L. Mittal,Inderbir Singh Bakshi,Jasjit Kaur Narang
  • Publisher : John Wiley & Sons
  • Release Date : 2020-05-26
  • Total pages : 432
  • ISBN : 0128225238
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Summary : Understanding the phenomenon of bioadhesion i.e. its theories or mechanism(s) are of critical importance in developing optimum bioadhesive polymers (used in bioadhesives). Such bioadhesive polymers are the key for exhibiting the process of bioadhesion, controlled/sustained release of drugs, and drug targeting. The use of bioadhesives restricts the ...