Computational Systems Biology of Cancer

Written By Emmanuel Barillot
Computational Systems Biology of Cancer
  • Publsiher : CRC Press
  • Release : 25 August 2012
  • ISBN : 1439831440
  • Pages : 461 pages
  • Rating : /5 from reviews
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Download or read book entitled Computational Systems Biology of Cancer by author: Emmanuel Barillot which was release on 25 August 2012 and published by CRC Press with total page 461 pages . This book available in PDF, EPUB and Kindle Format. The future of cancer research and the development of new therapeutic strategies rely on our ability to convert biological and clinical questions into mathematical models—integrating our knowledge of tumour progression mechanisms with the tsunami of information brought by high-throughput technologies such as microarrays and next-generation sequencing. Offering promising insights on how to defeat cancer, the emerging field of systems biology captures the complexity of biological phenomena using mathematical and computational tools. Novel Approaches to Fighting Cancer Drawn from the authors’ decade-long work in the cancer computational systems biology laboratory at Institut Curie (Paris, France), Computational Systems Biology of Cancer explains how to apply computational systems biology approaches to cancer research. The authors provide proven techniques and tools for cancer bioinformatics and systems biology research. Effectively Use Algorithmic Methods and Bioinformatics Tools in Real Biological Applications Suitable for readers in both the computational and life sciences, this self-contained guide assumes very limited background in biology, mathematics, and computer science. It explores how computational systems biology can help fight cancer in three essential aspects: Categorising tumours Finding new targets Designing improved and tailored therapeutic strategies Each chapter introduces a problem, presents applicable concepts and state-of-the-art methods, describes existing tools, illustrates applications using real cases, lists publically available data and software, and includes references to further reading. Some chapters also contain exercises. Figures from the text and scripts/data for reproducing a breast cancer data analysis are available at www.cancer-systems-biology.net.

Computational Systems Biology of Cancer

Computational Systems Biology of Cancer
  • Author : Emmanuel Barillot,Laurence Calzone,Philippe Hupe,Jean-Philippe Vert,Andrei Zinovyev
  • Publisher : CRC Press
  • Release Date : 2012-08-25
  • Total pages : 461
  • ISBN : 1439831440
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Summary : The future of cancer research and the development of new therapeutic strategies rely on our ability to convert biological and clinical questions into mathematical models—integrating our knowledge of tumour progression mechanisms with the tsunami of information brought by high-throughput technologies such as microarrays and next-generation sequencing. Offering promising insights ...

Elements of Computational Systems Biology

Elements of Computational Systems Biology
  • Author : Huma M. Lodhi,Stephen H. Muggleton
  • Publisher : John Wiley & Sons
  • Release Date : 2010-03-25
  • Total pages : 400
  • ISBN : 1439831440
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Summary : Groundbreaking, long-ranging research in this emergent field that enables solutions to complex biological problems Computational systems biology is an emerging discipline that is evolving quickly due to recent advances in biology such as genome sequencing, high-throughput technologies, and the recent development of sophisticated computational methodologies. Elements of Computational Systems Biology ...

Computational Systems Biology

Computational Systems Biology
  • Author : Andres Kriete,Roland Eils
  • Publisher : Elsevier
  • Release Date : 2005-11-10
  • Total pages : 424
  • ISBN : 1439831440
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Summary : Systems Biology is concerned with the quantitative study of complex biosystems at the molecular, cellular, tissue, and systems scales. Its focus is on the function of the system as a whole, rather than on individual parts. This exciting new arena applies mathematical modeling and engineering methods to the study of ...

Computational Systems Biology Approaches in Cancer Research

Computational Systems Biology Approaches in Cancer Research
  • Author : Inna Kuperstein,Emmanuel Barillot
  • Publisher : CRC Press
  • Release Date : 2019-09-09
  • Total pages : 167
  • ISBN : 1439831440
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Summary : Praise for Computational Systems BiologyApproaches in Cancer Research: "Complex concepts are written clearly and with informative illustrations and useful links. The book is enjoyable to read yet provides sufficient depth to serve as a valuable resource for both students and faculty." — Trey Ideker, Professor of Medicine, UC Xan Diego, School ...

An Introduction to Computational Systems Biology

An Introduction to Computational Systems Biology
  • Author : Karthik Raman
  • Publisher : CRC Press
  • Release Date : 2021-05-31
  • Total pages : 358
  • ISBN : 1439831440
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Summary : "This is a very comprehensive read that provides a solid base in computational biology. The book is structured in 4 parts and 14 chapters which cover all the way from the more basic concepts to advanced material, including the state-of-the-art methodologies in synthetic and systems biology. This is a bedside book for ...

Transactions on Computational Systems Biology III

Transactions on Computational Systems Biology III
  • Author : Corrado Priami,Emanuela Merelli,Pedro Pablo Gonzalez,Andrea Omicini
  • Publisher : Springer Science & Business Media
  • Release Date : 2005-12-12
  • Total pages : 169
  • ISBN : 1439831440
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Summary : The LNCS journal Transactions on Computational Systems Biology is devoted to inter- and multidisciplinary research in the fields of computer science and life sciences and supports a paradigmatic shift in the techniques from computer and information science to cope with the new challenges arising from the systems-oriented point of view ...

Computational Systems Biology

Computational Systems Biology
  • Author : Paola Lecca,Angela Re,Adaoha Elizabeth Ihekwaba,Ivan Mura,Thanh-Phuong Nguyen
  • Publisher : Woodhead Publishing
  • Release Date : 2016-07-29
  • Total pages : 180
  • ISBN : 1439831440
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Summary : Computational Systems Biology: Inference and Modelling provides an introduction to, and overview of, network analysis inference approaches which form the backbone of the model of the complex behavior of biological systems. This book addresses the challenge to integrate highly diverse quantitative approaches into a unified framework by highlighting the relationships ...

Formal Methods for Computational Systems Biology

Formal Methods for Computational Systems Biology
  • Author : Marco Bernardo,Pierpaolo Degano,Gianluigi Zavattaro
  • Publisher : Springer
  • Release Date : 2008-05-31
  • Total pages : 527
  • ISBN : 1439831440
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Summary : This book presents a set of 14 papers accompanying the lectures of leading researchers given at the 8th edition of the International School on Formal Methods for the Design of Computer, Communication and Software Systems, SFM 2008, held in Bertinoro, Italy in June 2008. SFM 2008 was devoted to formal techniques for computational systems ...

Computational Systems Biology

Computational Systems Biology
  • Author : Juergen Eilsa,Elena Herzoga,Baerbel Felder,Christian Lawerenza,Roland Eils
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-11-26
  • Total pages : 548
  • ISBN : 1439831440
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Summary : Systems biology combines experimental and computational research to facilitate understanding of complex biological processes. In this chapter we describe data repositories, data standards, modeling, and visualization tools as prerequisites for systems biology research in order to help us to better study and understand biological processes. In addition, we propose improvements ...

Computational Systems Biology

Computational Systems Biology
  • Author : Roland Eils,Andres Kriete
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-11-26
  • Total pages : 548
  • ISBN : 1439831440
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Summary : Read online Computational Systems Biology written by Roland Eils,Andres Kriete, published by Elsevier Inc. Chapters which was released on 2013-11-26. Download full Computational Systems Biology Books now! Available in PDF, ePub and Kindle....

Computational Systems Biology

Computational Systems Biology
  • Author : Reinhard Laubenbacher,Pedro Mendes
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-11-26
  • Total pages : 548
  • ISBN : 1439831440
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Summary : Mathematical and statistical network modeling is an important step toward uncovering the organizational principles and dynamic behavior of biological networks. This chapter focuses on methods to construct discrete dynamic models of gene regulatory networks from experimental data sets, also sometimes referred to as top-down modeling or reverse engineering. Time-discrete dynamical ...

Computational Systems Biology

Computational Systems Biology
  • Author : Ursula Klingmüller,Marcel Schilling,Sofia Depner,Lorenza A. D’Alessandro
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-11-26
  • Total pages : 548
  • ISBN : 1439831440
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Summary : Cellular communication is mediated by extracellular stimuli that bind cellular receptors and activate intracellular signaling pathways. Principal biochemical reactions used for signal transduction are protein or lipid phosphorylation, proteolytic cleavage, protein degradation and complex formation mediated by protein-protein interactions. Within the nucleus, signaling pathways regulate transcription factor activity and gene ...

Exam Prep for Computational Systems Biology of Cancer

Exam Prep for  Computational Systems Biology of Cancer
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2021-05-09
  • Total pages : 212
  • ISBN : 1439831440
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Summary : Read online Exam Prep for Computational Systems Biology of Cancer written by , published by which was released on . Download full Exam Prep for Computational Systems Biology of Cancer Books now! Available in PDF, ePub and Kindle....

Computational Systems Biology Of Synaptic Plasticity Modelling Of Biochemical Pathways Related To Memory Formation And Impairement

Computational Systems Biology Of Synaptic Plasticity  Modelling Of Biochemical Pathways Related To Memory Formation And Impairement
  • Author : Kulasiri Don,He Yao
  • Publisher : #N/A
  • Release Date : 2017-06-09
  • Total pages : 364
  • ISBN : 1439831440
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Summary : This book demonstrates the power of mathematical thinking in understanding the biological complexity that exists within the brain. It looks at the latest research on modelling of biochemical pathways within synapses, and provides a clear background for the study of mathematical models related to systems biology. Discussion then focusses on ...

Transactions on Computational Systems Biology XII

Transactions on Computational Systems Biology XII
  • Author : Anonim
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-02-18
  • Total pages : 263
  • ISBN : 1439831440
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Summary : LNCS 5945...