Chromatin Signaling and Diseases

Written By Olivier Binda
Chromatin Signaling and Diseases
  • Publsiher : Academic Press
  • Release : 06 August 2016
  • ISBN : 012802609X
  • Pages : 466 pages
  • Rating : /5 from reviews
GET THIS BOOKChromatin Signaling and Diseases


Download or read book entitled Chromatin Signaling and Diseases by author: Olivier Binda which was release on 06 August 2016 and published by Academic Press with total page 466 pages . This book available in PDF, EPUB and Kindle Format. Chromatin Signaling and Diseases covers the molecular mechanisms that regulate gene expression, which govern everything from embryonic development, growth, and human pathologies associated with aging, such as cancer. This book helps researchers learn about or keep up with the quickly expanding field of chromatin signaling. After reading this book, clinicians will be more capable of explaining the mechanisms of gene expression regulation to their patients to reassure them about new drug developments that target chromatin signaling mechanisms. For example, several epigenetic drugs that act on chromatin signaling factors are in clinical trials or even approved for usage in cancer treatments, Alzheimer's, and Huntington's diseases. Other epigenetic drugs are in development to regulate various class of chromatin signaling factors. To keep up with this changing landscape, clinicians and doctors will need to stay familiar with genetic advances that translate to clinical practice, such as chromatin signaling. Although sequencing of the human genome was completed over a decade ago and its structure investigated for nearly half a century, molecular mechanisms that regulate gene expression remain largely misunderstood. An emerging concept called chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these, is reviewed in Chromatin Signaling and Diseases. Finally, the impact of gene expression defects associated with malfunctioning chromatin signaling is also explored. Explains molecular mechanisms that regulate gene expression, which governs everything from embryonic development, growth, and human pathologies associated with aging Educates clinicians and researchers about chromatin signaling, a molecular mechanism that is changing our understanding of human pathology Explores the addition and removal of chemical modifications on histones, the proteins that specifically recognize these, and the impact of gene expression defects associated with malfunctioning chromatin signaling Helps researchers learn about the quickly expanding field of chromatin signaling

Chromatin Signaling and Diseases

Chromatin Signaling and Diseases
  • Author : Olivier Binda,Martin Ernesto Fernandez-Zapico
  • Publisher : Academic Press
  • Release Date : 2016-08-06
  • Total pages : 466
  • ISBN : 012802609X
GET BOOK

Summary : Chromatin Signaling and Diseases covers the molecular mechanisms that regulate gene expression, which govern everything from embryonic development, growth, and human pathologies associated with aging, such as cancer. This book helps researchers learn about or keep up with the quickly expanding field of chromatin signaling. After reading this book, clinicians ...

Chromatin Signaling and Neurological Disorders

Chromatin Signaling and Neurological Disorders
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-05-24
  • Total pages : 378
  • ISBN : 012802609X
GET BOOK

Summary : Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, ...

Stanford Bulletin

Stanford Bulletin
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2006
  • Total pages : 212
  • ISBN : 012802609X
GET BOOK

Summary : Read online Stanford Bulletin written by , published by which was released on 2006. Download full Stanford Bulletin Books now! Available in PDF, ePub and Kindle....

Gene Regulation Epigenetics and Hormone Signaling

Gene Regulation  Epigenetics and Hormone Signaling
  • Author : Subhrangsu S. Mandal
  • Publisher : John Wiley & Sons
  • Release Date : 2017-10-23
  • Total pages : 668
  • ISBN : 012802609X
GET BOOK

Summary : The first of its kind, this reference gives a comprehensive but concise introduction to epigenetics before covering the many interactions between hormone regulation and epigenetics at all levels. The contents are very well structured with no overlaps between chapters, and each one features supplementary material for use in presentations. Throughout, ...

Signal Transduction Pathways Chromatin Structure and Gene Expression Mechanisms as Therapeutic Targets

Signal Transduction Pathways  Chromatin Structure  and Gene Expression Mechanisms as Therapeutic Targets
  • Author : Marc Diederich
  • Publisher : Unknown
  • Release Date : 2004
  • Total pages : 674
  • ISBN : 012802609X
GET BOOK

Summary : This volume describes recent findings in the field of fundamental signal transduction mechanisms, including protein kinesis as therapeutic targets as well as applied research toward angiogenesis, apoptosis, and chemopreventive agents....

Monaldi Archives for Chest Disease

Monaldi Archives for Chest Disease
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2003
  • Total pages : 212
  • ISBN : 012802609X
GET BOOK

Summary : Read online Monaldi Archives for Chest Disease written by , published by which was released on 2003. Download full Monaldi Archives for Chest Disease Books now! Available in PDF, ePub and Kindle....

Epigenetics in Cardiac Disease

Epigenetics in Cardiac Disease
  • Author : Johannes Backs,Timothy A. McKinsey
  • Publisher : Springer
  • Release Date : 2016-11-21
  • Total pages : 316
  • ISBN : 012802609X
GET BOOK

Summary : This book describes important advances in our understanding of how environmental conditions affect cardiac gene expression through epigenetic mechanisms. Further, it discusses the roles of chromatin modifications (in particular DNA methylation and histone modifications) and of chromatin regulators in the context of cardiac diseases. The book provides readers with an ...

Encyclopedia of Endocrine Diseases E Im

Encyclopedia of Endocrine Diseases  E Im
  • Author : Luciano Martini
  • Publisher : Academic Press
  • Release Date : 2004
  • Total pages : 2400
  • ISBN : 012802609X
GET BOOK

Summary : The Encyclopedia of Endocrine Diseases is an authoritative reference developed by 16 international experts who recruited the world's top scientists for contributions. This stellar reference work focuses on nearly 500 endocrine diseases addressing everything from acromeglay, diabetes, hypertension, osteoporosis, thyroid disease, Von Hippel-Lindau Disease, unexplained weight loss, to androgen related disorders. This ...

Jak Stat Signaling From Basics to Disease

Jak Stat Signaling   From Basics to Disease
  • Author : Thomas Decker,Mathias Müller
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-06-06
  • Total pages : 450
  • ISBN : 012802609X
GET BOOK

Summary : JAK tyrosine kinases and STAT transcription factors constitute a signaling pathway, which is activated by cytokines. By activating gene transcription it regulates essential biological responses to environmental cues. The Jak-Stat pathway is involved in the regulation of cell development, differentiation, proliferation and apoptosis. Improper function may contribute to hematopoietic malignancies ...

Genomic dark matter implications for understanding human disease mechanisms diagnostics and cures

Genomic    dark matter     implications for understanding human disease mechanisms  diagnostics  and cures
  • Author : Philipp Kapranov
  • Publisher : Frontiers E-books
  • Release Date : 2021-04-18
  • Total pages : 212
  • ISBN : 012802609X
GET BOOK

Summary : The vast majority of the human genome has been historically ignored from the point of view of molecular mechanisms of disease, diagnostics and potential therapeutic targets. The predominant focus of disease research has traditionally been placed on the protein-coding regions of the human genome, which account for only ~4-5% of ...

Epigenetics in Health and Disease

Epigenetics in Health and Disease
  • Author : Igor Kovalchuk,Olga Kovalchuk
  • Publisher : FT Press
  • Release Date : 2012
  • Total pages : 598
  • ISBN : 012802609X
GET BOOK

Summary : "After reviewing the field's history and context, the authors introduce and explain each key epigenetic mechanism. Next, they extensively discuss the roles these mechanisms may play in inheritance, development, health and disease, behavior, evolution, ecology, and the interactions of individual organisms with their environments"--Cover, p. [4]....

Neurodegenerative Diseases

Neurodegenerative Diseases
  • Author : Donald Brian Calne
  • Publisher : Saunders
  • Release Date : 1994
  • Total pages : 954
  • ISBN : 012802609X
GET BOOK

Summary : Here is a comprehensive book dedicated to normal neural aging and neurodegenerative disorders. The first section of the text discusses topics relevant to the basic science of neurodegenerative disease such as organic and inorganic neurotoxins, virus and neurodegeneration, lewy bodies, and neurofibrillary tangle. Dr. Calne and over 75 international experts next ...

A Molecular Biology Approach to Parkinson s Disease

A Molecular Biology Approach to Parkinson s Disease
  • Author : Peter Jenner
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 95
  • ISBN : 012802609X
GET BOOK

Summary : Read online A Molecular Biology Approach to Parkinson s Disease written by Peter Jenner, published by which was released on 2000. Download full A Molecular Biology Approach to Parkinson s Disease Books now! Available in PDF, ePub and Kindle....

The Role of WNT Signaling Pathway Defects in the Pathogenesis of Ovarian Endometrioid Adenocarcinomas

The Role of WNT Signaling Pathway Defects in the Pathogenesis of Ovarian Endometrioid Adenocarcinomas
  • Author : Neali Danielle Hendrix
  • Publisher : Unknown
  • Release Date : 2007
  • Total pages : 212
  • ISBN : 012802609X
GET BOOK

Summary : Read online The Role of WNT Signaling Pathway Defects in the Pathogenesis of Ovarian Endometrioid Adenocarcinomas written by Neali Danielle Hendrix, published by which was released on 2007. Download full The Role of WNT Signaling Pathway Defects in the Pathogenesis of Ovarian Endometrioid Adenocarcinomas Books now! Available in PDF, ePub and ...

Diseases of Children in the Subtropics and Tropics

Diseases of Children in the Subtropics and Tropics
  • Author : Hubert Carey Trowell,Derrick Brian Jelliffe
  • Publisher : Unknown
  • Release Date : 1958
  • Total pages : 919
  • ISBN : 012802609X
GET BOOK

Summary : Read online Diseases of Children in the Subtropics and Tropics written by Hubert Carey Trowell,Derrick Brian Jelliffe, published by which was released on 1958. Download full Diseases of Children in the Subtropics and Tropics Books now! Available in PDF, ePub and Kindle....