Genome Editing

Written By Kursad Turksen
Genome Editing
  • Publsiher : Springer
  • Release : 09 August 2016
  • ISBN : 3319341480
  • Pages : 166 pages
  • Rating : /5 from reviews
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Download or read book entitled Genome Editing by author: Kursad Turksen which was release on 09 August 2016 and published by Springer with total page 166 pages . This book available in PDF, EPUB and Kindle Format. This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of reporter stem cells; the text contextualizes these methods in treatment of cardiovascular disease, diabetes mellitus, retinitis pigmentosa, and others. The final chapters round out the book with a discussion of controversies and future directions. Genome Editing is an essential, of-the-moment contribution to this rapidly growing field. Drawing from a wealth of international perspectives, it presents novel techniques and applications for the engineering of the human genome. This book is essential reading for all clinicians and researchers in stem cells, regenerative medicine, genomics, biochemical and biomedical engineering- especially those interested in learning more about genome editing and applying it in a targeted, specific way.

Genome Editing

Genome Editing
  • Author : Kursad Turksen
  • Publisher : Springer
  • Release Date : 2016-08-09
  • Total pages : 166
  • ISBN : 3319341480
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Summary : This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of ...

Genome Editing

Genome Editing
  • Author : Kiran Musunuru
  • Publisher : Academic Press
  • Release Date : 2021-03-05
  • Total pages : 230
  • ISBN : 3319341480
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Summary : Genome Editing: A Practical Guide to Research and Clinical Applications is geared towards investigators interested in learning how to use CRISPR-Cas9-based technologies, with a focus on cardiovascular research and clinical applications. Covering a range of topics from the basics of genome editing to design considerations, to assessments and applications, ...

Establishment of the Human Cardiac Models Using Gene Editing and Reprogramming in Human Pluripotent Stem Cells to Understand the Putative Functions of the G protein Coupled Receptor Kinase 5 Polymorphism GRK5 L41

Establishment of the Human Cardiac Models Using Gene Editing and Reprogramming in Human Pluripotent Stem Cells to Understand the Putative Functions of the G protein Coupled Receptor Kinase 5 Polymorphism  GRK5 L41
  • Author : Minh Duc Hoang
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 212
  • ISBN : 3319341480
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Summary : Read online Establishment of the Human Cardiac Models Using Gene Editing and Reprogramming in Human Pluripotent Stem Cells to Understand the Putative Functions of the G protein Coupled Receptor Kinase 5 Polymorphism GRK5 L41 written by Minh Duc Hoang, published by which was released on 2017. Download full Establishment of the Human ...

The Future of Pharmaceutical Product Development and Research

The Future of Pharmaceutical Product Development and Research
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2020-09-02
  • Total pages : 976
  • ISBN : 3319341480
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Summary : The Future of Pharmaceutical Product Development and Research examines the latest developments in the pharmaceutical sciences, also highlighting key developments, research and future opportunities. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of the product development phase ...

Genome Editing and Engineering

Genome Editing and Engineering
  • Author : Krishnarao Appasani
  • Publisher : Cambridge University Press
  • Release Date : 2018-07-31
  • Total pages : 586
  • ISBN : 3319341480
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Summary : A complete guide to endonuclease-based genomic engineering, from basic science to application in disease biology and clinical treatment....

Congestive Heart Failure and Cardiac Transplantation

Congestive Heart Failure and Cardiac Transplantation
  • Author : Daniel J. Garry,Robert F. Wilson,Zeev Vlodaver
  • Publisher : Springer
  • Release Date : 2017-06-01
  • Total pages : 572
  • ISBN : 3319341480
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Summary : This book is a comprehensive overview of heart failure and cardiac transplantation and integrates scientific and clinical information about the physiology, pathophysiology, diagnosis, and treatment of this disorder. Organized into five parts, it reviews the history and basic mechanisms of heart failure; etiology of heart failure; heart failure disease progression; ...

Molecular Basis of Cardiovascular Disease

Molecular Basis of Cardiovascular Disease
  • Author : Kenneth R. Chien,Eugene Braunwald
  • Publisher : Unknown
  • Release Date : 1999
  • Total pages : 637
  • ISBN : 3319341480
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Summary : Covering the molecular basis of heart disease, this text evaluates topics such as genetic mapping approaches in inherited cardiovascular disorders, and driving mechanisms in the transition from cardiac hypertrophy to heart failure....

Genome Engineering via CRISPR Cas9 System

Genome Engineering via CRISPR Cas9 System
  • Author : Vijai Singh,Pawan K. Dhar
  • Publisher : Academic Press
  • Release Date : 2020-02-18
  • Total pages : 384
  • ISBN : 3319341480
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Summary : Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can ...

Translational Cardiometabolic Genomic Medicine

Translational Cardiometabolic Genomic Medicine
  • Author : Annabelle Rodriguez-Oquendo
  • Publisher : Academic Press
  • Release Date : 2015-09-07
  • Total pages : 352
  • ISBN : 3319341480
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Summary : Translational Cardiometabolic Genomic Medicine, edited by Dr. Annabelle Rodriguez-Oquendo, is an important resource to postgraduate (medical, dental and graduate) students, postdoctoral fellows, basic scientists, and physician scientists seeking to understand and expand their knowledge base in the field of genomic medicine as it is applied to cardiometabolic diseases. This handbook ...

Cardiovascular Engineering A Protective Approach

Cardiovascular Engineering  A Protective Approach
  • Author : Shu Liu
  • Publisher : McGraw Hill Professional
  • Release Date : 2020-06-12
  • Total pages : 496
  • ISBN : 3319341480
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Summary : Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. Cardiovascular engineering principles and practices with a focus on disease prevention Aimed at advanced students taking cardiovascular, regenerative, and tissue engineering courses, Cardiovascular ...

A Handbook of Mouse Models of Cardiovascular Disease

A Handbook of Mouse Models of Cardiovascular Disease
  • Author : Qinbo Xu
  • Publisher : John Wiley & Sons Incorporated
  • Release Date : 2006
  • Total pages : 387
  • ISBN : 3319341480
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Summary : The availability of well-defined genetic strains and the ability to create transgenic and knockout mice makes mouse models extremely valuable biomedical tools. Their suitability as an experimental system for cardiovascular research depends on the individual investigator’s ability to manipulate the mice surgically. Many mouse models require microsurgical techniques, which ...

Genetic Engineering News

Genetic Engineering News
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 212
  • ISBN : 3319341480
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Summary : Read online Genetic Engineering News written by , published by which was released on 2000. Download full Genetic Engineering News Books now! Available in PDF, ePub and Kindle....

Textbook of Gene Therapy

Textbook of Gene Therapy
  • Author : Kewal K. Jain
  • Publisher : Seattle ; Toronto : Hogrefe & Huber
  • Release Date : 1998
  • Total pages : 434
  • ISBN : 3319341480
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Summary : During the past eight years following initial gene therapy experiments, more than 200 clinical protocols have been submitted worldwide and more than 2000 patients have been treated. Although a lot remains to be accomplished before gene therapy becomes a standard medical practice, enough information has accumulated to justify a textbook on the ...

Cardiovascular and Pulmonary Physical Therapy Third Edition

Cardiovascular and Pulmonary Physical Therapy  Third Edition
  • Author : William DeTurk,Lawerence Cahalin
  • Publisher : McGraw Hill Professional
  • Release Date : 2018-01-12
  • Total pages : 800
  • ISBN : 3319341480
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Summary : A comprehensive, up-to-date textbook spanning the entire scope of cardiovascular and pulmonary practice A Doody’s Core Title for 2019! Cardiovascular and Pulmonary Physical Therapy, Third Edition reflects the broadest possible spectrum of cardiovascular and pulmonary practice and draws upon the expertise of a carefully selected team of world-renowned contributors. This ...

Establishment of a PRKAG2 Cardiac Syndrome Disease Model and Mechanism Study Using Human Induced Pluripotent Stem Cells

Establishment of a PRKAG2 Cardiac Syndrome Disease Model and Mechanism Study Using Human Induced Pluripotent Stem Cells
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 3319341480
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Summary : Abstract: PRKAG2 cardiac syndrome is a distinct form of human cardiomyopathy characterized by cardiac hypertrophy, ventricular pre-excitation and progressive cardiac conduction disorder. However, it remains unclear how mutations in the PRKAG2 gene give rise to such a complicated disease. To investigate the underlying molecular mechanisms, we generated disease-specific hiPSC-derived cardiomyocytes ...