Brain Lipids in Synaptic Function and Neurological Disease

Written By Jacques Fantini
Brain Lipids in Synaptic Function and Neurological Disease
  • Publsiher : Academic Press
  • Release : 12 May 2015
  • ISBN : 0128004924
  • Pages : 398 pages
  • Rating : /5 from reviews
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Download or read book entitled Brain Lipids in Synaptic Function and Neurological Disease by author: Jacques Fantini which was release on 12 May 2015 and published by Academic Press with total page 398 pages . This book available in PDF, EPUB and Kindle Format. Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer’s, Creutzfeldt-Jakob’s and Parkinson’s. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders. Written to provide a "hands-on" approach for readers Biochemical structures explained with molecular models, and molecular mechanisms explained with simple drawings Step-by-step guide to memorize and draw lipid structures Each chapter features a content summary, up-to-date references for additional study, and a key experiment with an explanation of the technique

Brain Lipids in Synaptic Function and Neurological Disease

Brain Lipids in Synaptic Function and Neurological Disease
  • Author : Jacques Fantini,Nouara Yahi
  • Publisher : Academic Press
  • Release Date : 2015-05-12
  • Total pages : 398
  • ISBN : 0128004924
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Summary : Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, ...

Beneficial Effects of Fish Oil on Human Brain

Beneficial Effects of Fish Oil on Human Brain
  • Author : Akhlaq A. Farooqui
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-07-14
  • Total pages : 396
  • ISBN : 0128004924
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Summary : It is becoming increasingly evident that the deficiency of n-3 fatty acids in diet is not only associated with cardiovascular diseases, but also involved in stroke, epilepsy and other neurological and neurodegenerative diseases, such as Alzheimer disease, Parkinson disease, and peroxisomal diseases. In his newest book, Beneficial Effects of Fish ...

Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases

Neurochemical Aspects of Neurotraumatic and Neurodegenerative Diseases
  • Author : Akhlaq A. Farooqui
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-09-02
  • Total pages : 401
  • ISBN : 0128004924
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Summary : Collectively, neurodegenerative diseases are characterized by chronic and progressive loss of neurons in discrete areas of the brain, producing debilitating symptoms such as dementia, loss of memory, loss of sensory or motor capability, decreased overall quality of life eventually leading to premature death. Two types of cell death are known ...

Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases

Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases
  • Author : Tahira Farooqui,Akhlaq A. Farooqui
  • Publisher : Academic Press
  • Release Date : 2017-10-24
  • Total pages : 484
  • ISBN : 0128004924
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Summary : Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain, along with its beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (...

Pharmacological Modification of Excitatory Hippocampal Ca1 Synapses in Pathological Models of Neuroinflammation and Alzheimer s Disease

Pharmacological Modification of Excitatory Hippocampal Ca1 Synapses in Pathological Models of Neuroinflammation and Alzheimer s Disease
  • Author : Keng-Yu Chang
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 212
  • ISBN : 0128004924
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Summary : "An integral component of synaptic transmission is the capacity of synapses to adjust their structural and functional properties in response to the activities of other neurons in a process called synaptic plasticity. Changes in excitatory synapses can occur on dendritic spines, postsynaptic sites of the majority of excitatory synapses in ...

Curcumin for Neurological and Psychiatric Disorders

Curcumin for Neurological and Psychiatric Disorders
  • Author : Tahira Farooqui,Akhlaq A. Farooqui
  • Publisher : Academic Press
  • Release Date : 2019-03-16
  • Total pages : 544
  • ISBN : 0128004924
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Summary : Curcumin for Neurological and Psychiatric Disorders: Neurochemical and Pharmacological Properties focuses on the different molecular mechanisms underlying curcumin-mediated beneficial effects in neurological diseases. The book's editors discuss the neurochemical and pharmacological properties of curcumin, followed by the effect of curcumin in neurotraumatic diseases, neurodegenerative diseases, and neuropsychiatric diseases. The book ...

Lipid Mediators and Their Metabolism in the Brain

Lipid Mediators and Their Metabolism in the Brain
  • Author : Akhlaq A. Farooqui
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-08-12
  • Total pages : 327
  • ISBN : 0128004924
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Summary : Lipid Mediators and Their Metabolism in the Brain presents readers with cutting edge and comprehensive information not only on the synthesis and degradation of glycerophospholipid-, sphingolipid-, and cholesterol-derived lipid mediators, but also their involvement in neurological disorders. It is hoped that this monograph will be useful not only to postgraduate ...

Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders

Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders
  • Author : Akhlaq A. Farooqui
  • Publisher : Academic Press
  • Release Date : 2020-03-20
  • Total pages : 498
  • ISBN : 0128004924
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Summary : Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders provides an overview on the risk factors for insulin resistance in visceral and neurological disorders. The book focuses on molecular mechanisms and signal transduction processes associated with the links. The comprehensive information in this monograph will not only help ...

Hot Topics in Neural Membrane Lipidology

Hot Topics in Neural Membrane Lipidology
  • Author : Akhlaq A. Farooqui
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-04-05
  • Total pages : 408
  • ISBN : 0128004924
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Summary : Glycerophospholipid and sphingolipid-derived lipid mediators facilitate the transfer of messages not only from one cell to another but also from one subcellular organelle to another. These molecules are not only components of neural membranes but also storage depots for lipid mediators. Information on the generation and involvement of lipid mediators ...

Molecular Aspects of Neurodegeneration Neuroprotection and Regeneration in Neurological Disorders

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  • Author : Akhlaq A. Farooqui
  • Publisher : Academic Press
  • Release Date : 2020-09-07
  • Total pages : 400
  • ISBN : 0128004924
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Summary : Molecular Aspects of Neurodegeneration, Neuroprotection, and Regeneration in Neurological Disorders presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of neurological disorders. The book covers information on signal transduction processes associated with neurochemistry of neurological disorders, including neurodegenerative, neurotraumatic, and neuropsychiatric disorders. The book also ...

Gut Microbiota in Neurologic and Visceral Diseases

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  • Author : Tahira Farooqui,Akhlaq A. Farooqui
  • Publisher : Academic Press
  • Release Date : 2021-03-24
  • Total pages : 386
  • ISBN : 0128004924
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Summary : Gut Microbiota in Neurologic and Visceral Diseases presents readers with comprehensive information on the involvement of microbiota in the pathogenesis of neurological disorders. Chapters cover the effect of microbiota on the development of visceral (obesity, type 2 diabetes, heart disease) and neurological disorders (Alzheimer’s disease, Parkinson’s, depression, anxiety, and ...

Sterol Regulation of Ion Channels

Sterol Regulation of Ion Channels
  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2017-08-29
  • Total pages : 306
  • ISBN : 0128004924
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Summary : Sterol Regulation of Ion Channels, Volume 80, the latest in the Current Topics in Membranes series provides outstanding content to the scientific community on relevant topics that relate to the broad field of membranes. Topics of note in this new release include Membrane structure and general mechanisms of sterol regulation of ...

Trace Amines and Neurological Disorders

Trace Amines and Neurological Disorders
  • Author : Tahira Farooqui,Akhlaq A. Farooqui
  • Publisher : Academic Press
  • Release Date : 2016-07-12
  • Total pages : 432
  • ISBN : 0128004924
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Summary : Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors explores trace amines which, under normal conditions, are present in the mammalian brain and peripheral nervous tissues at very low (nanomolar) concentrations. However, in a diverse array of human pathologies ranging from substance abuse, depression, attention deficit hyperactivity disorder, eating ...

Molecular Organization of Membranes Where Biology Meets Biophysics

Molecular Organization of Membranes  Where Biology Meets Biophysics
  • Author : Marek Cebecauer,David Holowka
  • Publisher : Frontiers Media SA
  • Release Date : 2018-02-07
  • Total pages : 212
  • ISBN : 0128004924
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Summary : Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed of lipids and proteins influencing each other. Local membrane composition and properties define its molecular organisation and, in this way, ...

Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases

Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases
  • Author : Tahira Farooqui,Akhlaq A. Farooqui
  • Publisher : Academic Press
  • Release Date : 2017-10-24
  • Total pages : 474
  • ISBN : 0128004924
GET BOOK

Summary : Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain, along with its beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (...