Basics of Chimeric Antigen Receptor CAR Immunotherapy

Written By Mumtaz Y. Balkhi
Basics of Chimeric Antigen Receptor  CAR  Immunotherapy
  • Publsiher : Academic Press
  • Release : 31 July 2019
  • ISBN : 0128197471
  • Pages : 92 pages
  • Rating : /5 from reviews
GET THIS BOOKBasics of Chimeric Antigen Receptor CAR Immunotherapy


Download or read book entitled Basics of Chimeric Antigen Receptor CAR Immunotherapy by author: Mumtaz Y. Balkhi which was release on 31 July 2019 and published by Academic Press with total page 92 pages . This book available in PDF, EPUB and Kindle Format. Basics of Chimeric Antigen Receptor (CAR) Immunotherapy presents the latest on how T cell adoptive immunotherapy has progressed in its ultimate goal of curing metastatic malignant cancers. Recent clinical data obtained with checkpoint receptor blockade inhibitors and chimeric antigen receptor (CAR) therapy has been especially promising, thus generating renewed hope that we may be on the verge of finally curing cancer. Over the years, huge progress has been made in controlling several stage IV metastasized cancers through the clinical application of checkpoint receptor inhibitory drugs and CAR-Therapy that has seen unprecedented interest in the immunotherapy field. Presents the first book to provide a basic understanding of chimeric antigen receptor (CARs) design, production and clinical application protocols Provides unique authority as the editor has worked directly with CARs Discusses the challenges encountered in actual clinical trials and how these challenges can be overcome Includes a full chapter on various challenges researchers should expect to encounter in the CAR-therapy field

Basics of Chimeric Antigen Receptor CAR Immunotherapy

Basics of Chimeric Antigen Receptor  CAR  Immunotherapy
  • Author : Mumtaz Y. Balkhi
  • Publisher : Academic Press
  • Release Date : 2019-07-31
  • Total pages : 92
  • ISBN : 0128197471
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Summary : Basics of Chimeric Antigen Receptor (CAR) Immunotherapy presents the latest on how T cell adoptive immunotherapy has progressed in its ultimate goal of curing metastatic malignant cancers. Recent clinical data obtained with checkpoint receptor blockade inhibitors and chimeric antigen receptor (CAR) therapy has been especially promising, thus generating renewed hope ...

Part I Understanding Cancer Immunotherapy A brief Review Part II What is Chimeric Antigen Receptor CAR T Cell Therapy An Emerging Cancer Treatment Modality

Part I  Understanding Cancer Immunotherapy  A brief Review  Part II     What is Chimeric Antigen Receptor  CAR  T  Cell Therapy     An Emerging Cancer Treatment Modality
  • Author : Dr. Hakim Saboowala
  • Publisher : Dr.Hakim Saboowala
  • Release Date : 2020-05-12
  • Total pages : 212
  • ISBN : 0128197471
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Summary : Part I- Understanding Cancer Immunotherapy: A brief Review. Immunotherapy, also called biologic therapy, is a type of cancer treatment that boosts the body's natural defenses to fight cancer. It uses substances made by the body or in a laboratory to improve or restore immune system function. Immunotherapy may work by: ...

Chimeric Antigen Receptor CAR T cell Immunotherapy for MUC1 positive Breast Cancer

Chimeric Antigen Receptor  CAR  T cell Immunotherapy for MUC1 positive Breast Cancer
  • Author : Artemis Gavriil
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 212
  • ISBN : 0128197471
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Summary : Read online Chimeric Antigen Receptor CAR T cell Immunotherapy for MUC1 positive Breast Cancer written by Artemis Gavriil, published by which was released on 2018. Download full Chimeric Antigen Receptor CAR T cell Immunotherapy for MUC1 positive Breast Cancer Books now! Available in PDF, ePub and Kindle....

Chimeric Antigen Receptor T Cell Therapies for Cancer E Book

Chimeric Antigen Receptor T Cell Therapies for Cancer E Book
  • Author : Daniel W. Lee,Nirali N. Shah
  • Publisher : Elsevier Health Sciences
  • Release Date : 2019-11-30
  • Total pages : 244
  • ISBN : 0128197471
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Summary : From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive view of CAR modified T-cells in a concise and practical format. Providing authoritative guidance on the implementation and management of CAR T-cell therapy from Drs. Daniel W. Lee and Nirali ...

Defining Optimal T Cell Characteristics for Pediatric Chimeric Antigen Receptor CAR T Cell Trials

Defining Optimal T Cell Characteristics for Pediatric Chimeric Antigen Receptor  CAR  T Cell Trials
  • Author : Julie M. Rivers
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 23
  • ISBN : 0128197471
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Summary : Background: Engineered chimeric antigen receptor (CAR) T cells have emerged as a powerful, highly personalized immunotherapy in pediatric cancer. Early phase clinical trials using CAR T cells targeting CD19 have resulted in complete response (CR) rates as high as 93% in children with relapsed and refractory acute lymphoblastic leukemia (ALL). Despite ...

The Basics of Cancer Immunotherapy

The Basics of Cancer Immunotherapy
  • Author : Haidong Dong,Svetomir N. Markovic
  • Publisher : Springer
  • Release Date : 2018-01-05
  • Total pages : 160
  • ISBN : 0128197471
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Summary : This book provides patients and their physicians (especially “non-oncologist” health care providers) with a clear and concise introduction to cancer immunotherapy, which, unlike traditional forms of cancer therapy, acts by boosting the patient’s own immune system to fight cancer. The unique features of cancer immunotherapy make its management, monitoring ...

Fast Facts CAR T Cell Therapy

Fast Facts  CAR T Cell Therapy
  • Author : R.J. Buka,A.J. Kansagra
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2021-01-26
  • Total pages : 72
  • ISBN : 0128197471
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Summary : Chimeric antigen receptor (CAR) T cells are genetically engineered immune cells that can seek out and destroy cancer cells. The results from their use in cancer immunotherapy have been very promising, but treatment is often associated with frequent, serious short-term toxicities. 'Fast Facts: CAR-T Therapy' explains what CAR T cells ...

CAR T Cell Therapies for Non Hematopoietic Malignancies Taking Off The Training Wheels

CAR T Cell Therapies for Non Hematopoietic Malignancies  Taking Off The Training Wheels
  • Author : Avery Dexter Posey, Jr.,John - Maher,Marcela V. Maus
  • Publisher : Frontiers Media SA
  • Release Date : 2020-04-24
  • Total pages : 212
  • ISBN : 0128197471
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Summary : Chimeric antigen receptor (CAR) T cell therapies for leukemia (e.g. tisagenlecleucel) and lymphoma (e.g. axicabtagene ciloleucel) have recently received regulatory approval in the United States. Phase I/II trials have demonstrated complete remission of refractory or relapsed tumors in 50% - 94% patients. However, the clinical successes of engineered T ...

Verzeichnis der Adressen unserer im Milit rdienst stehenden Mitbr der der th ringischen Franziskanerprovinz

Verzeichnis der Adressen unserer im Milit  rdienst stehenden Mitbr  der  der th  ringischen Franziskanerprovinz
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1917
  • Total pages : 46
  • ISBN : 0128197471
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Summary : Read online Verzeichnis der Adressen unserer im Milit rdienst stehenden Mitbr der der th ringischen Franziskanerprovinz written by , published by which was released on 1917. Download full Verzeichnis der Adressen unserer im Milit rdienst stehenden Mitbr der der th ringischen Franziskanerprovinz Books now! Available in PDF, ePub and Kindle....

Immunotherapy Using Chimeric Antigen Receptor Macrophage

Immunotherapy Using Chimeric Antigen Receptor Macrophage
  • Author : Peng Fei Huang
  • Publisher : Unknown
  • Release Date : 2019
  • Total pages : 44
  • ISBN : 0128197471
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Summary : Chimeric antigen receptor (CAR) T cell immunotherapy has become one of the most prominent and leading cancer therapies due to its remarkable success in targeting hematological malignancies. Unfortunately, CAR-T cell immunotherapy has not had the same amount of success in solid tumors due to the challenging tumor's immunosuppressive microenvironment. Therefore, ...

Targeting the Disialoganglioside GD2 with Chimeric Antigen Receptor T Cells for Immunotherapy in Diffuse Midline Gliomas and Exploration of Neuron opc Synaptic Connectivity in the Context of Adaptive Myelination

Targeting the Disialoganglioside GD2 with Chimeric Antigen Receptor T Cells for Immunotherapy in Diffuse Midline Gliomas and Exploration of Neuron opc Synaptic Connectivity in the Context of Adaptive Myelination
  • Author : Christopher Mount
  • Publisher : Unknown
  • Release Date : 2020
  • Total pages : 212
  • ISBN : 0128197471
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Summary : Histone 3 K27M mutated diffuse midline glioma (H3K27M DMG) is a universally fatal pediatric brain tumor. Despite improved understanding of the molecular origins of this disease, translations to improvement in clinical outcomes have yet to materialize. To date, there has been little target exploration for immunotherapy applications in ...

Fast Facts CAR T Cell Therapy

Fast Facts  CAR T Cell Therapy
  • Author : Richard J. Buka,Ankit J. Kansagra
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2021-02-28
  • Total pages : 72
  • ISBN : 0128197471
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Summary : Chimeric antigen receptor (CAR) T cells are genetically engineered immune cells that can seek out and destroy cancer cells. The results from their use in cancer immunotherapy have been very promising, but treatment is often associated with frequent, serious short-term toxicities. 'Fast Facts: CAR-T Therapy' explains what CAR T cells ...

Genome Engineering to Expand Applications of Human T cell Immunotherapy

Genome Engineering to Expand Applications of Human T cell Immunotherapy
  • Author : Alexandra E. Grier
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 102
  • ISBN : 0128197471
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Summary : Adoptive T-cell therapy, particularly chimeric antigen receptor (CAR) therapy, is a revolutionary and quickly-evolving means of treating cancer patients who can no longer be helped by standard therapies. In multiple clinical trials, including our own at Seattle Children’s Hospital, CD19 CAR therapy for B-cell leukemia and lymphoma has achieved ...

Current Immunotherapeutic Strategies in Cancer

Current Immunotherapeutic Strategies in Cancer
  • Author : Matthias Theobald
  • Publisher : Springer Nature
  • Release Date : 2019-08-31
  • Total pages : 187
  • ISBN : 0128197471
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Summary : This book offers a comprehensive review of recent advances in cancer immunotherapy, and explores the value and limitations of the most effective current therapeutic strategies and emerging treatment modalities. It discusses in detail the successes achieved using monoclonal antibodies (mAbs), including developments with regard to conjugated mAbs and also bispecific ...

Williams Hematology 10th Edition

Williams Hematology  10th Edition
  • Author : Kenneth Kaushansky,Marshall A. Lichtman,Josef T. Prchal,Marcel M. Levi,Linda J. Burns
  • Publisher : McGraw Hill Professional
  • Release Date : 2021-01-14
  • Total pages : 2528
  • ISBN : 0128197471
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Summary : The landmark text that has guided generations of hematologists and related practitioners―updated with the latest research findings and improved format and presentation Long revered for its comprehensiveness and extraordinary depth of detail, Williams Hematology provides essential coverage of the origins, pathophysiological mechanisms, and management of benign and malignant disorders ...