Basic Principles of Drug Discovery and Development

Written By Benjamin Blass
Basic Principles of Drug Discovery and Development
  • Publsiher : Elsevier
  • Release : 24 April 2015
  • ISBN : 012411525X
  • Pages : 580 pages
  • Rating : /5 from reviews
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Download or read book entitled Basic Principles of Drug Discovery and Development by author: Benjamin Blass which was release on 24 April 2015 and published by Elsevier with total page 580 pages . This book available in PDF, EPUB and Kindle Format. Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, providing comprehensive explanations of enabling technologies such as high throughput screening, structure based drug design, molecular modeling, pharmaceutical profiling, and translational medicine, all areas that have become critical steps in the successful development of marketable therapeutics. The text introduces the fundamental principles of drug discovery and development, also discussing important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles in pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. It is designed to enable new scientists to rapidly understand the key fundamentals of drug discovery, including pharmacokinetics, toxicology, and intellectual property." Provides a clear explanation of how the pharmaceutical industry works Explains the complete drug discovery process, from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual propertyIdeal for anyone interested in learning about the drug discovery process and those contemplating careers in the industry Explains the transition process from academia or other industries

Basic Principles of Drug Discovery and Development

Basic Principles of Drug Discovery and Development
  • Author : Benjamin Blass
  • Publisher : Elsevier
  • Release Date : 2015-04-24
  • Total pages : 580
  • ISBN : 012411525X
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Summary : Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, providing comprehensive explanations of enabling technologies such as high throughput screening, structure based drug design, molecular modeling, pharmaceutical profiling, and translational medicine, all areas that have become critical steps in ...

Drug Discovery and Development

Drug Discovery and Development
  • Author : H. P. Rang,Daniel Vasella
  • Publisher : Churchill Livingstone
  • Release Date : 2006
  • Total pages : 346
  • ISBN : 012411525X
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Summary : 'Drug Discovery and Development' describes the huge complexities involved in bringing a drug to market and how new molecular understanding and techniques can make the process more targeted and successful....

Chemical Biology

Chemical Biology
  • Author : Natanya Civjan
  • Publisher : John Wiley & Sons
  • Release Date : 2012-08-07
  • Total pages : 524
  • ISBN : 012411525X
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Summary : An authoritative look at the application of chemical biology in drug discovery and development Based on the award-winning Wiley Encyclopedia of Chemical Biology published in 2008, this book explores the role of chemical biology in drug discovery and development. The first part of the book reviews key principles and techniques used ...

Introduction to Biological and Small Molecule Drug Research and Development

Introduction to Biological and Small Molecule Drug Research and Development
  • Author : C. Robin Ganellin,Roy Jefferis,Stanley M. Roberts
  • Publisher : Academic Press
  • Release Date : 2013-05-07
  • Total pages : 472
  • ISBN : 012411525X
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Summary : Introduction to Biological and Small Molecule Drug Research and Development provides, for the first time, an introduction to the science behind successful pharmaceutical research and development programs. The book explains basic principles, then compares and contrasts approaches to both biopharmaceuticals (proteins) and small molecule drugs, presenting an overview of the ...

Principles of Anticancer Drug Development

Principles of Anticancer Drug Development
  • Author : Elizabeth Garrett-Mayer
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-12-29
  • Total pages : 674
  • ISBN : 012411525X
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Summary : A practical guide to the design, conduction, analysis and reporting of clinical trials with anticancer drugs....

Plant Bioactives and Drug Discovery

Plant Bioactives and Drug Discovery
  • Author : Valdir Cechinel-Filho
  • Publisher : John Wiley & Sons
  • Release Date : 2012-05-22
  • Total pages : 565
  • ISBN : 012411525X
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Summary : An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform ...

Principles of Cancer Treatment and Anticancer Drug Development

Principles of Cancer Treatment and Anticancer Drug Development
  • Author : Wolfgang Link
  • Publisher : Springer Nature
  • Release Date : 2019-09-10
  • Total pages : 145
  • ISBN : 012411525X
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Summary : This book explains how current medicines against cancer work and how we find new ones. It provides an easy-to-understand overview of current options to treat patients with cancer, which includes Surgery, Radiation therapy, Chemotherapy, Targeted therapy and Immunotherapy. The efficiency of all these treatments is limited by the capacity of ...

Cancer Drug Design and Discovery

Cancer Drug Design and Discovery
  • Author : Stephen Neidle
  • Publisher : Academic Press
  • Release Date : 2013-09-30
  • Total pages : 640
  • ISBN : 012411525X
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Summary : Cancer Drug Design and Discovery, Second Edition is an important reference on the underlying principles for the design and subsequent development of new anticancer small molecule agents. New chapters have been added to this edition on areas of particular interest and therapeutic promise, including cancer genomics and personalized medicine, DNA-targeted ...

General and Molecular Pharmacology

General and Molecular Pharmacology
  • Author : Francesco Clementi,Guido Fumagalli
  • Publisher : John Wiley & Sons
  • Release Date : 2015-07-01
  • Total pages : 784
  • ISBN : 012411525X
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Summary : With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the fundamental basis for proper clinical use- without neglecting clinical application, toxicology and pharmacokinetics. • Covers cell and ...

Drug Discovery and Development Drug Development

Drug Discovery and Development  Drug Development
  • Author : Mukund S. Chorghade
  • Publisher : Wiley-Interscience
  • Release Date : 2007-08-31
  • Total pages : 400
  • ISBN : 012411525X
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Summary : From first principles to real-world applications-here is the first comprehensive guide to drug discovery and development Modern drug discovery and development require the collaborative efforts of specialists in a broadarray of scientific, technical, and business disciplines-from biochemistry to molecular biology, organic chemistry to medicinal chemistry, pharmacology to marketing. Yet surprisingly, ...

Principles of Clinical Pharmacology

Principles of Clinical Pharmacology
  • Author : Arthur J. Atkinson, Jr.,Darrell R. Abernethy,Charles E. Daniels,Robert Dedrick,Sanford P. Markey
  • Publisher : Elsevier
  • Release Date : 2011-04-28
  • Total pages : 568
  • ISBN : 012411525X
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Summary : This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice ...

Drug Discovery and Development Volume 1

Drug Discovery and Development  Volume 1
  • Author : Mukund S. Chorghade
  • Publisher : John Wiley & Sons
  • Release Date : 2006-07-18
  • Total pages : 476
  • ISBN : 012411525X
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Summary : This two volume set provides a comprehensive account of the entiresequence of operations involved in discovering a drug through theactual delivery of the drug to clinicians and medicalpractitioners. Includes case studies of the discovery of erythromycin analogs(antibiotics), Tagamet, and Ultiva (remifentanil) Discusses the discovery of agents for the treatment ...

Principles of CNS Drug Development

Principles of CNS Drug Development
  • Author : John Kelly
  • Publisher : John Wiley & Sons
  • Release Date : 2009-10-27
  • Total pages : 324
  • ISBN : 012411525X
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Summary : This title acts as a primer, giving students and newcomers to the field an opportunity to learn about the breadth of the CNS drug discovery. The book outlines the core processes in drug discovery and development for CNS disorders, from evaluating drugs for desirable efficacy, safety and pharmacokinetic features in ...

Pharmacokinetics and Metabolism in Drug Design

Pharmacokinetics and Metabolism in Drug Design
  • Author : Dennis A. Smith,Charlotte Allerton,Amit S. Kalgutkar,Han van de Waterbeemd,Don K. Walker
  • Publisher : John Wiley & Sons
  • Release Date : 2012-05-14
  • Total pages : 268
  • ISBN : 012411525X
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Summary : In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have been made, with new topics such as pro-drugs, active metabolites ...

Interagency Coordination in Drug Research and Regulation

Interagency Coordination in Drug Research and Regulation
  • Author : United States. Congress. Senate. Committee on Government Operations
  • Publisher : Unknown
  • Release Date : 1963
  • Total pages : 212
  • ISBN : 012411525X
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Summary : Read online Interagency Coordination in Drug Research and Regulation written by United States. Congress. Senate. Committee on Government Operations, published by which was released on 1963. Download full Interagency Coordination in Drug Research and Regulation Books now! Available in PDF, ePub and Kindle....