Annotating New Genes

Written By Shizuka Uchida
Annotating New Genes
  • Publsiher : Elsevier
  • Release : 06 August 2012
  • ISBN : 1908818123
  • Pages : 196 pages
  • Rating : /5 from reviews
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Download or read book entitled Annotating New Genes by author: Shizuka Uchida which was release on 06 August 2012 and published by Elsevier with total page 196 pages . This book available in PDF, EPUB and Kindle Format. In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to the analysis of evolutionary-conserved, heart-enriched genes with unknown functions, offering a step-by-step description of the procedure from screening to validation. The book begins by offering an introduction to the databases and software available, before moving on to cover programming guidelines, including a specific case study on the use of C-It for in silico screening. The second half of the book offers a step-by-step guide to experimental validation concepts and procedures, as well as an overview of additional potential applications of this approach in the field of stem cells and tissue regeneration, before a concluding chapter summarises the concepts and theories presented. Focuses not only on screening but also on biological validations Provides details of databases and software (web interface) products for biologists with minimal computation skills Offers a step-by-step outline of the procedure involved

Annotating New Genes

Annotating New Genes
  • Author : Shizuka Uchida
  • Publisher : Elsevier
  • Release Date : 2012-08-06
  • Total pages : 196
  • ISBN : 1908818123
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Summary : In recent years, a number of academic and commercial software packages and databases have been developed for the analysis and screening of biological data; however, the usability of these data is compromised by so-called novel genes to which no biological function is assigned. Annotating new genes outlines an approach to ...

Development of New Tools and Pipelines for Plant Bioinformatics Applications

Development of New Tools and Pipelines for Plant Bioinformatics Applications
  • Author : Omar M. Darwish
  • Publisher : Unknown
  • Release Date : 2014
  • Total pages : 140
  • ISBN : 1908818123
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Summary : Blueberry is an economically and nutritionally important small fruit crop, native to North America. As with many crops, extreme low temperature can affect blueberry crop yield negatively and cause major losses to growers. For this reason, blueberry breeding programs have focused on developing improved cultivars with broader climatic adaptation. To ...

IMG ER

IMG ER
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 212
  • ISBN : 1908818123
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Summary : A rapidly increasing number of microbial genomes are sequenced by organizations worldwide and are eventually included into various public genome data resources. The quality of the annotations depends largely on the original dataset providers, with erroneous or incomplete annotations often carried over into the public resources and difficult to correct. ...

An Integrated Approach to Enhancing Functional Annotation of Sequences for Data Analysis of a Transcriptome

An Integrated Approach to Enhancing Functional Annotation of Sequences for Data Analysis of a Transcriptome
  • Author : Matthew Morritt Hindle
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 212
  • ISBN : 1908818123
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Summary : Given the ever increasing quantity of sequence data, functional annotation of new gene sequences persists as being a significant challenge for bioinformatics. This is a particular problem for transcriptomics studies in crop plants where large genomes and evolutionarily distant model organisms, means that identifying the function of a given gene ...

Modern Genome Annotation

Modern Genome Annotation
  • Author : D. Frishman,Alfonso Valencia
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-10-02
  • Total pages : 490
  • ISBN : 1908818123
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Summary : An accurate description of current scientific developments in the field of bioinformatics and computational implementation is presented by research of the BioSapiens Network of Excellence. Bioinformatics is essential for annotating the structure and function of genes, proteins and the analysis of complete genomes and to molecular biology and biochemistry. Included ...

Genome Research

Genome Research
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 1908818123
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Summary : Read online Genome Research written by , published by which was released on 2008. Download full Genome Research Books now! Available in PDF, ePub and Kindle....

Database Annotation in Molecular Biology

Database Annotation in Molecular Biology
  • Author : Arthur M. Lesk
  • Publisher : John Wiley & Sons
  • Release Date : 2005-09-01
  • Total pages : 266
  • ISBN : 1908818123
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Summary : Two factors dominate current molecular biology: the amount of raw data is increasing very rapidly and successful applications in biomedical research require carefully curated and annotated databases. The quality of the experimental data -- especially nucleic acid sequences -- is satisfactory; however, annotations depend on features inferred from the data ...

Gene Annotation and Disease Gene Prediction from an Integrated Functional Linkage Gene Network

Gene Annotation and Disease Gene Prediction from an Integrated Functional Linkage Gene Network
  • Author : Bolan Linghu
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 290
  • ISBN : 1908818123
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Summary : Abstract: In the postgenomic era, it remains a challenging task to understand the cellular functions of genes and how the dysfunction of a gene relates to a disease. Since genes work cooperatively for particular cellular tasks, a functional linkage network (FLN) can be used for function-related studies. In this network, ...

Reannotation and Extended Community Resources for the Genome of the Non seed Plant Physcomitrella Patens Provide Insights Into the Evolution of Plant Gene Structures and Functions

Reannotation and Extended Community Resources for the Genome of the Non seed Plant Physcomitrella Patens Provide Insights Into the Evolution of Plant Gene Structures and Functions
  • Author : Andreas D. Zimmer,Daniel Lang,Karol Buchta,Stefan A. Rensing,Ralf Reski
  • Publisher : Unknown
  • Release Date : 2013
  • Total pages : 212
  • ISBN : 1908818123
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Summary : Read online Reannotation and Extended Community Resources for the Genome of the Non seed Plant Physcomitrella Patens Provide Insights Into the Evolution of Plant Gene Structures and Functions written by Andreas D. Zimmer,Daniel Lang,Karol Buchta,Stefan A. Rensing,Ralf Reski, published by which was released on 2013. Download full ...

Automatic Annotation of Multigene Families the Case of Peroxidases

Automatic Annotation of Multigene Families  the Case of Peroxidases
  • Author : Nizar Fawal
  • Publisher : Unknown
  • Release Date : 2013
  • Total pages : 155
  • ISBN : 1908818123
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Summary : Gene families are groups of homologous genes with a common ancestor that are likely to have highly similar sequences and functions. In our team, we are mainly interested in one of these families, the peroxidase superfamily. Peroxidases are universal enzymes present in all organisms where they typically catalyze the reduction ...

Transcription of Human specific Duplicate Genes

Transcription of Human specific Duplicate Genes
  • Author : Max L. Dougherty
  • Publisher : Unknown
  • Release Date : 2018
  • Total pages : 162
  • ISBN : 1908818123
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Summary : In this work, I set out to characterize new genes contained specifically within the human genome but absent from any other, including our closest evolutionary cousins. Our interest in these genes is twofold: First, gene duplication is a fundamental process by which evolutionary innovations at the organismal level arise; and ...

Algal Functional Annotation Tool

Algal Functional Annotation Tool
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2012
  • Total pages : 212
  • ISBN : 1908818123
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Summary : Abstract BACKGROUND: Progress in genome sequencing is proceeding at an exponential pace, and several new algal genomes are becoming available every year. One of the challenges facing the community is the association of protein sequences encoded in the genomes with biological function. While most genome assembly projects generate annotations for ...

Genesmith

Genesmith
  • Author : Ravi Dandekar
  • Publisher : Unknown
  • Release Date : 2016
  • Total pages : 212
  • ISBN : 1908818123
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Summary : Modern gene prediction, otherwise known as ab initio gene annotation, has yet to progress to a level of accuracy where it can replace the more costly process of manual curation through laboratory experiments. Gene annotation software utilizes machine learning approaches to model genes using Hidden Markov Models (HMMs) in order ...

Genome Annotation and Finding Repetitive DNA Elements

Genome Annotation and Finding Repetitive DNA Elements
  • Author : Renu Rawat
  • Publisher : Unknown
  • Release Date : 2014-06-03
  • Total pages : 44
  • ISBN : 1908818123
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Summary : Bachelor Thesis from the year 2014 in the subject Computer Science - Bioinformatics, grade: 8.26, Lovely Professional University, course: b.tech honors biotechnology, language: English, abstract: As the number of genomes sequenced is increasing at high rate, there is a need of gene prediction method which is quick, reliable, inexpensive. In such ...

Comparative Annotation Toolkit CAT Simultaneous Clade and Personal Genome Annotation

Comparative Annotation Toolkit  CAT    Simultaneous Clade and Personal Genome Annotation
  • Author : Ian Fiddes
  • Publisher : Unknown
  • Release Date : 2017
  • Total pages : 214
  • ISBN : 1908818123
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Summary : The recent introductions of low-cost, long-read and read-cloud sequencing technologies coupled with intense efforts to develop efficient algorithms have made affordable, high-quality de-novo sequence assembly a realistic proposition. The result is an explosion of new, ultra contiguous genome assemblies. To compare these genomes we need robust methods for genome annotation. ...