An Innovative Approach to Understanding and Treating Cancer

Written By Tomas Koltai
An Innovative Approach to Understanding and Treating Cancer
  • Publsiher : Academic Press
  • Release : 15 February 2020
  • ISBN : 9780128190593
  • Pages : 320 pages
  • Rating : /5 from reviews
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Download or read book entitled An Innovative Approach to Understanding and Treating Cancer by author: Tomas Koltai which was release on 15 February 2020 and published by Academic Press with total page 320 pages . This book available in PDF, EPUB and Kindle Format. The New pH-Centric Paradigm In Cancer Research: From Etiopathogenesis To New Therapeutic Avenues describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient, when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognised as one of the most selective and differential hallmarks of all cancer cells and tissues, being the opposite of the condition found in normal tissues and a potential target in order to achieve either a stable disease or even regression with no toxicity. The book discusses topics such as lactic acid and its transport system in the pH paradigm; mechanisms to decrease extra cellular pH and increase intracellular pH; NHE-1 activity in cancer; carbonic anhydrases; vacuolar ATPase proton pump; and the sodium-bicarbonate cotransporter system. Additionally, it discusses complementary pharmacological interventions and cellular acidification and extracellular alkalinisation as a new and integral approach to cancer treatment. Analyzes thoroughly the mechanisms that lead to the inversion of pH gradient in cancer tissues Summarizes almost 100 years of research on pH inversion in cancer in one single source, discussing the most relevant and updated researches in the field Proposes new efficient treatments against cancer using pH inversion mechanisms, either with new drugs like proton transport inhibitors and proton pump inhibitors (PTIs and PPIs) as well as with repurposed drugs

An Innovative Approach to Understanding and Treating Cancer

An Innovative Approach to Understanding and Treating Cancer
  • Author : Tomas Koltai,Stephan J Reshkin,Salvador Harguindey
  • Publisher : Academic Press
  • Release Date : 2020-02-15
  • Total pages : 320
  • ISBN : 9780128190593
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Summary : The New pH-Centric Paradigm In Cancer Research: From Etiopathogenesis To New Therapeutic Avenues describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient, when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognised ...

An Innovative Approach to Understanding and Treating Cancer Targeting pH

An Innovative Approach to Understanding and Treating Cancer  Targeting pH
  • Author : Tomas Koltai,Stephan J. Reshkin,Salvador Harguindey
  • Publisher : Academic Press
  • Release Date : 2020-01-16
  • Total pages : 574
  • ISBN : 9780128190593
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Summary : An Innovative Approach to Studying and Treating Cancer: Targeting pH describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognized as one of ...

Prostate Cancer Metabolism

Prostate Cancer Metabolism
  • Author : Tomas Koltai,Stephan J. Reshkin,Fatima Baltazar,Larry Fliegel
  • Publisher : Academic Press
  • Release Date : 2021-07-01
  • Total pages : 416
  • ISBN : 9780128190593
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Summary : Prostate Cancer Metabolism: From Biochemistry to Therapeutics shows the peculiarities of prostate cancer metabolism, emphasizing the targetable aspects – that have not been considered in conventional treatment protocols. The book specifically addresses treatment of the castration-resistant stage of prostate cancer proposing many repurposed drugs and nutraceuticals to complement, not replace, standard ...

Prostate Cancer Metabolism

Prostate Cancer Metabolism
  • Author : Tomas Koltai,Stephan J. Reshkin,Fatima Baltazar,Larry Fliegel
  • Publisher : Elsevier
  • Release Date : 2021-07-15
  • Total pages : 200
  • ISBN : 9780128190593
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Summary : Prostate Cancer Metabolism: From Biochemistry to Therapeutics shows the peculiarities of prostate cancer metabolism, emphasizing the targetable aspects - that have not been considered in conventional treatment protocols. The book specifically addresses treatment of the castration-resistant stage of prostate cancer proposing many repurposed drugs and nutraceuticals to complement, not replace, ...

Nanotechnology

Nanotechnology
  • Author : Bhaskar Mazumder,Subhabrata Ray,Paulami Pal,Yashwant Pathak
  • Publisher : CRC Press
  • Release Date : 2019-03-18
  • Total pages : 455
  • ISBN : 9780128190593
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Summary : Today we find the applications of nanotechnology in all spheres of life. Nanotechnology: Therapeutic, Nutraceutical and Cosmetic Advances discusses recent advances in the field, particularly with therapeutics, nutraceuticals and cosmetic sciences. Therapeutics is an area which has perhaps benefitted the most, although nanoscience and technology have quietly entered the realms ...

Fighting Cancer

Fighting Cancer
  • Author : Robert Gorter, M.D., Ph.D.,Erik Peper, Ph.D.
  • Publisher : North Atlantic Books
  • Release Date : 2011-05-31
  • Total pages : 384
  • ISBN : 9780128190593
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Summary : Fighting Cancer describes the Gorter Model, an integrative, nontoxic approach to cancer treatment that mobilizes the immune system. It was developed by Robert Gorter, MD, PhD, who in 1976 recovered from Stage IV testicular cancer by using nontoxic treatment and no chemotherapy or radiation. Based on self-experience, extensive research, and decades ...

Cancer Research Program Annual Report to the California State Legislature

Cancer Research Program Annual Report to the California State Legislature
  • Author : Cancer Research Program (Calif.)
  • Publisher : Unknown
  • Release Date : 2000
  • Total pages : 212
  • ISBN : 9780128190593
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Summary : Read online Cancer Research Program Annual Report to the California State Legislature written by Cancer Research Program (Calif.), published by which was released on 2000. Download full Cancer Research Program Annual Report to the California State Legislature Books now! Available in PDF, ePub and Kindle....

Wiley Encyclopedia of Chemical Biology Volume 3

Wiley Encyclopedia of Chemical Biology  Volume 3
  • Author : Tadhg P. Begley
  • Publisher : Wiley
  • Release Date : 2009-02-03
  • Total pages : 828
  • ISBN : 9780128190593
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Summary : The first major reference at the interface of chemistry, biology, and medicine Chemical biology is a rapidly developing field that uses the principles, tools, and language of chemistry to answer important questions in the life sciences. It has enabled researchers to gather critical information about the molecular biology of the ...

pH Interfering Agents as Chemosensitizers in Cancer Therapy

pH Interfering Agents as Chemosensitizers in Cancer Therapy
  • Author : Claudiu Supuran,Simone Carradori
  • Publisher : Academic Press
  • Release Date : 2020-09-15
  • Total pages : 228
  • ISBN : 9780128190593
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Summary : pH Interfering Agents as Chemosensitizers In Cancer Therapy, Volume Thirteen, provides a detailed overview of the chemosensitizers for the treatment of cancer spanning from biochemical and structural features to pharmacology and drug-design, including technological applications. The book is structured with innovative outlines and a distinction between experimental and clinical results. ...

Advanced Drug Delivery Systems in the Management of Cancer

Advanced Drug Delivery Systems in the Management of Cancer
  • Author : Kamal Dua,Meenu Mehta,Terezinha de Jesus Andreoli Pinto,Lisa G. Pont,Kylie A. Williams,Michael Rathbone
  • Publisher : Elsevier
  • Release Date : 2021-06-24
  • Total pages : 572
  • ISBN : 9780128190593
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Summary : Advanced Drug Delivery Systems in the Management of Cancer discusses recent developments in nanomedicine and nano-based drug delivery systems used in the treatment of cancers affecting the blood, lungs, brain, and kidneys. The research presented in this book includes international collaborations in the area of novel drug delivery for the ...

Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy

Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy
  • Author : Andrea Bonetti,Roberto Leone,Franco Muggia,Stephen B. Howell
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-01-09
  • Total pages : 398
  • ISBN : 9780128190593
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Summary : Cisplatin, the first member of the family of platinum-containing chemotherapeutic agents, was discovered by Barnett Rosenberg in 1965 and approved by the FDA for marketing in 1978. After 30 years of use in the clinic, cisplatin remains a central element of many treatment regimens. Cisplatin is still an irreplaceable component of a regimen ...

Novel Gene Therapy Approaches

Novel Gene Therapy Approaches
  • Author : Ming Wei,David Good
  • Publisher : BoD – Books on Demand
  • Release Date : 2013-02-13
  • Total pages : 406
  • ISBN : 9780128190593
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Summary : Gene therapy has the potential to be a tailor-made therapeutic with increased specificity and decreased side effects that can offer a "cure" for many disorders. The aim of this book is to provide up-to-date reviews of the rapidly growing field of gene therapy. Chapters cover a large range of topics ...

Cancer Treatment

Cancer Treatment
  • Author : Letícia Rangel
  • Publisher : BoD – Books on Demand
  • Release Date : 2013-05-09
  • Total pages : 630
  • ISBN : 9780128190593
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Summary : Cancer Treatment: Conventional and Innovative Approaches is an attempt to integrate into a book volume the various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field. The volume is presented in six sections: i) Section 1: Cancer treatment: Conventional and innovative pharmacological approaches; ...

Severe Combined Immunodeficiency New Insights for the Healthcare Professional 2011 Edition

Severe Combined Immunodeficiency  New Insights for the Healthcare Professional  2011 Edition
  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-01-09
  • Total pages : 29
  • ISBN : 9780128190593
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Summary : Severe Combined Immunodeficiency: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Severe Combined Immunodeficiency in a compact format. The editors have built Severe Combined Immunodeficiency: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ ...

Therapeutic Targeting of Cancer Stem Like Cells CSC The Current State of the Art

Therapeutic Targeting of Cancer Stem Like Cells  CSC      The Current State of the Art
  • Author : Cyril Corbet,Alexandre Prieur
  • Publisher : Frontiers Media SA
  • Release Date : 2020-04-03
  • Total pages : 212
  • ISBN : 9780128190593
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Summary : Read online Therapeutic Targeting of Cancer Stem Like Cells CSC The Current State of the Art written by Cyril Corbet,Alexandre Prieur, published by Frontiers Media SA which was released on 2020-04-03. Download full Therapeutic Targeting of Cancer Stem Like Cells CSC The Current State of the Art Books ...