AGO Driven Non Coding RNAs

Written By Bibekanand Mallick
AGO Driven Non Coding RNAs
  • Publsiher : Academic Press
  • Release : 20 January 2019
  • ISBN : 0128156708
  • Pages : 387 pages
  • Rating : /5 from reviews
GET THIS BOOKAGO Driven Non Coding RNAs


Download or read book entitled AGO Driven Non Coding RNAs by author: Bibekanand Mallick which was release on 20 January 2019 and published by Academic Press with total page 387 pages . This book available in PDF, EPUB and Kindle Format. The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily confined to transfer RNAs and, ribosomal RNAs, which act as the messengers of the protein synthesis and allow translation of genetic information encoded by DNA into proteins. In recent years, the integration of high-throughput genomic technologies with molecular biology and omics sciences have revolutionized the fields of ncRNA research by identifying the hidden treasures of several new types of ncRNAs encoded in the genomes of several organisms and decrypting their versatile roles in gene expression and epigenetics. Among these, two small endogenous ncRNAs, namely microRNAs (miRNAs) and piwi-interacting RNAs (piRNAs) that drive argonaute (AGO) family of proteins namely Ago and Piwi respectively and silence the expression of genes have geared up molecular and disease biology research in recent years. Both miRNAs and piRNAs are expressed in higher eukaryotes, including human and act as cellular rheostats by regulating the expression of significant fraction of genes encoded in the genomes. The aberrant expressions of these small ncRNAs within the cells cause various abnormalities and diseases including cancer. Manipulating their aberrant expression or function can serve as potential novel diagnostic/prognostic biomarkers and bring in new therapeutic strategies for multiple human diseases. This can be further translated from bench-side to clinic for improving human health. This book captures the essence of the pioneering work of some of the world’s leading researchers showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs and piRNAs highlighting their potential towards the diagnosis and therapeutics of various diseases. The book is geared towards scientists, students, and will particularly appeal to active investigators in RNA biology, molecular biology, cancer research as well as clinicians and will provide them a comprehensive view of recent discoveries and research progresses to utilize miRNAs, piRNAs and their interacting proteins, Ago and Piwi for diagnosis, prognosis and therapeutics of diseases. Provides a unified cutting-edge resource for both miRNAs and piRNAs, two promising AGO-clade small ncRNAs, their functions and potential applications Showcase high-throughput technologies and other approaches for discovery of these small ncRNAs and their targets Unveils the diverse molecular mechanisms by which miRNAs and piRNAs regulate gene expression in animal cells Showcase recent discoveries on involvement of Argonaute and Piwi proteins in different biological processes and diseases as well as their possible use in diagnosis Report breakthroughs in the use of small ncRNAs for diagnosis and personalized therapy

AGO Driven Non Coding RNAs

AGO Driven Non Coding RNAs
  • Author : Bibekanand Mallick
  • Publisher : Academic Press
  • Release Date : 2019-01-20
  • Total pages : 387
  • ISBN : 0128156708
GET BOOK

Summary : The ‘RNA world’ hypothesis that proposed RNA molecules as the first form of genetic material was put forwarded in the late 1980s but got impetus only recently when high-throughput sequencing technologies began unearthing new types of non-coding RNA (ncRNA) transcripts in higher eukaryotes. Till then, research on ncRNAs were primarily ...

Essentials of Cancer Genomic Computational Approaches and Precision Medicine

 Essentials of Cancer Genomic  Computational Approaches and Precision Medicine
  • Author : Nosheen Masood,Saima Shakil Malik
  • Publisher : Springer Nature
  • Release Date : 2020-03-20
  • Total pages : 499
  • ISBN : 0128156708
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Summary : This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent ...

Non coding RNAs and Cancer

Non coding RNAs and Cancer
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  • Publisher : Springer Science & Business Media
  • Release Date : 2013-10-28
  • Total pages : 284
  • ISBN : 0128156708
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Summary : The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and its implications in cancer are emerging as well, suggesting a broader than anticipated involvement of ...

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Regulation by non coding RNAs Volume 1
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  • Publisher : MDPI
  • Release Date : 2018-10-09
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Summary : Printed Edition of the Special Issue Published in IJMS...

Genome Research

Genome Research
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 212
  • ISBN : 0128156708
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Summary : Read online Genome Research written by , published by which was released on 2009. Download full Genome Research Books now! Available in PDF, ePub and Kindle....

Regulatory RNAs in the Nervous System 2nd Edition

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  • Publisher : Frontiers Media SA
  • Release Date : 2018-11-13
  • Total pages : 346
  • ISBN : 0128156708
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Summary : Until about a decade ago, the non-coding part of the genome was considered without function. RNA sequencing studies have shown, however, that a considerable part of the non-coding genome is transcribed and that these non-coding RNAs (nc-RNAs) can regulate gene expression. Almost on weekly basis, new findings reveal the regulatory ...

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  • Author : Flavia Bazzoni,Daniela Bosisio
  • Publisher : Frontiers Media SA
  • Release Date : 2020-12-11
  • Total pages : 212
  • ISBN : 0128156708
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Summary : Read online Regulation of Soluble Immune Mediators by Non Coding RNAs written by Flavia Bazzoni,Daniela Bosisio, published by Frontiers Media SA which was released on 2020-12-11. Download full Regulation of Soluble Immune Mediators by Non Coding RNAs Books now! Available in PDF, ePub and Kindle....

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  • Publisher : Wiley-Interscience
  • Release Date : 2007
  • Total pages : 289
  • ISBN : 0128156708
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Summary : To understand the brain and its devastating diseases, we need to reveal the mechanisms that produce it and the ways in which it can constantly change throughout a lifetime. This book features a timely and insightful discussion between developmental neurobiologists and clinicians who deal with disorders of the nervous system. ...

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  • Publisher : Wiley-Blackwell
  • Release Date : 2008-04-14
  • Total pages : 238
  • ISBN : 0128156708
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Summary : Leading researchers in the life sciences and engineers involved in research of transport phenomena in biological systems have contributed chapters that identify, analyze, and modify the control and regulation mechanisms of transport phenomena in biological systems, with particular emphasis on the cardiac system. Included in the contributions to this volume ...

Regulatory RNAs in the Nervous System

Regulatory RNAs in the Nervous System
  • Author : Tommaso Pizzorusso,Alessandro Cellerino, Laure Bally-Cuif
  • Publisher : Frontiers Media SA
  • Release Date : 2015-05-08
  • Total pages : 344
  • ISBN : 0128156708
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Summary : Until about a decade ago, the non-coding part of the genome was considered without function. RNA sequencing studies have shown, however, that a considerable part of the non-coding genome is transcribed and that these non-coding RNAs (nc-RNAs) can regulate gene expression. Almost on weekly basis, new findings reveal the regulatory ...

Transactions

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  • Author : Biochemical Society (Great Britain)
  • Publisher : Unknown
  • Release Date : 2008
  • Total pages : 212
  • ISBN : 0128156708
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Summary : Read online Transactions written by Biochemical Society (Great Britain), published by which was released on 2008. Download full Transactions Books now! Available in PDF, ePub and Kindle....

Philosophical Transactions of the Royal Society of London

Philosophical Transactions of the Royal Society of London
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2009
  • Total pages : 212
  • ISBN : 0128156708
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Summary : Read online Philosophical Transactions of the Royal Society of London written by , published by which was released on 2009. Download full Philosophical Transactions of the Royal Society of London Books now! Available in PDF, ePub and Kindle....

Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America
  • Author : National Academy of Sciences (U.S.)
  • Publisher : Unknown
  • Release Date : 2002
  • Total pages : 212
  • ISBN : 0128156708
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Summary : Read online Proceedings of the National Academy of Sciences of the United States of America written by National Academy of Sciences (U.S.), published by which was released on 2002. Download full Proceedings of the National Academy of Sciences of the United States of America Books now! Available in PDF, ePub ...

Nature

Nature
  • Author : Sir Norman Lockyer
  • Publisher : Unknown
  • Release Date : 1869
  • Total pages : 212
  • ISBN : 0128156708
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Summary : Read online Nature written by Sir Norman Lockyer, published by which was released on 1869. Download full Nature Books now! Available in PDF, ePub and Kindle....

New Technology Japan

New Technology Japan
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1996
  • Total pages : 212
  • ISBN : 0128156708
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Summary : Read online New Technology Japan written by , published by which was released on 1996. Download full New Technology Japan Books now! Available in PDF, ePub and Kindle....