A Comprehensive Guide to Toxicology in Preclinical Drug Development

Written By Ali S. Faqi
A Comprehensive Guide to Toxicology in Preclinical Drug Development
  • Publsiher : Academic Press
  • Release : 16 November 2012
  • ISBN : 0123878152
  • Pages : 885 pages
  • Rating : /5 from reviews
GET THIS BOOKA Comprehensive Guide to Toxicology in Preclinical Drug Development


Download or read book entitled A Comprehensive Guide to Toxicology in Preclinical Drug Development by author: Ali S. Faqi which was release on 16 November 2012 and published by Academic Press with total page 885 pages . This book available in PDF, EPUB and Kindle Format. A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. Chapters written by world-renowned contributors who are experts in their fields Includes the latest research in preclinical drug testing and international guidelines Covers preclinical toxicology in small molecules and biologics in one single source

A Comprehensive Guide to Toxicology in Preclinical Drug Development

A Comprehensive Guide to Toxicology in Preclinical Drug Development
  • Author : Ali S. Faqi
  • Publisher : Academic Press
  • Release Date : 2012-11-16
  • Total pages : 885
  • ISBN : 0123878152
GET BOOK

Summary : A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide ...

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

A Comprehensive Guide to Toxicology in Nonclinical Drug Development
  • Author : Ali S. Faqi
  • Publisher : Academic Press
  • Release Date : 2016-11-03
  • Total pages : 986
  • ISBN : 0123878152
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Summary : A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem ...

Preclinical Development Handbook

Preclinical Development Handbook
  • Author : Shayne Cox Gad
  • Publisher : John Wiley & Sons
  • Release Date : 2008-03-21
  • Total pages : 1080
  • ISBN : 0123878152
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Summary : A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use ...

Genomic Biomarkers for Pharmaceutical Development

Genomic Biomarkers for Pharmaceutical Development
  • Author : Yihong Yao,Bahija Jallal,Koustubh Ranade
  • Publisher : Academic Press
  • Release Date : 2013-07-16
  • Total pages : 208
  • ISBN : 0123878152
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Summary : Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing ...

Accelerated Path to Cures

Accelerated Path to Cures
  • Author : Josep Bassaganya-Riera
  • Publisher : Springer
  • Release Date : 2018-04-25
  • Total pages : 82
  • ISBN : 0123878152
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Summary : Accelerated Path to Cures provides a transformative perspective on the power of combining advanced computational technologies, modeling, bioinformatics and machine learning approaches with nonclinical and clinical experimentation to accelerate drug development. This book discusses the application of advanced modeling technologies, from target identification and validation to nonclinical studies in animals ...

Flavonoid Pharmacokinetics

Flavonoid Pharmacokinetics
  • Author : Neal M. Davies,Jaime A. Yáñez
  • Publisher : John Wiley & Sons
  • Release Date : 2012-11-05
  • Total pages : 352
  • ISBN : 0123878152
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Summary : SETS FORTH A FRAMEWORK FOR THE ANALYSIS AND STUDY OF FLAVONOIDS More and more dietary supplements contain flavonoids. These products are typically viewed as food rather than drug products by regulatory agencies and therefore not subjected to rigorous clinical trials before they are marketed to the general public. As a ...

Preclinical Safety Evaluation of Biopharmaceuticals

Preclinical Safety Evaluation of Biopharmaceuticals
  • Author : Joy A. Cavagnaro
  • Publisher : John Wiley & Sons
  • Release Date : 2013-03-07
  • Total pages : 1064
  • ISBN : 0123878152
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Summary : "The goal is to provide a comprehensive reference book for thepreclinicaldiscovery and development scientist whoseresponsibilities span target identification, lead candidateselection, pharmacokinetics, pharmacology, and toxicology, and forregulatory scientists whose responsibilities include the evaluationof novel therapies." —From the Afterword by Anthony D. Dayan Proper preclinical safety evaluation can improve the predictivevalue, lessen ...

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
  • Author : Michelle A. Rudek,Cindy H. Chau,William D. Figg,Howard L. McLeod
  • Publisher : Springer Science & Business Media
  • Release Date : 2014-01-10
  • Total pages : 836
  • ISBN : 0123878152
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Summary : There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and ...

ADME Enabling Technologies in Drug Design and Development

ADME Enabling Technologies in Drug Design and Development
  • Author : Donglu Zhang,Sekhar Surapaneni
  • Publisher : John Wiley & Sons
  • Release Date : 2012-04-13
  • Total pages : 800
  • ISBN : 0123878152
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Summary : A comprehensive guide to cutting-edge tools in ADME research The last decade has seen tremendous progress in the developmentof analytical techniques such as mass spectrometry and molecularbiology tools, resulting in important advances in drug discovery,particularly in the area of absorption, distribution, metabolism,and excretion (ADME). ADME-Enabling Technologies in Drug ...

Development and Approval of Combination Products

Development and Approval of Combination Products
  • Author : Evan B. Siegel
  • Publisher : John Wiley & Sons
  • Release Date : 2008-06-09
  • Total pages : 216
  • ISBN : 0123878152
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Summary : A step-by-step, integrated approach for successful, FDA-approved combination drug products Using a proven integrated approach to combination drug development, this book guides you step by step through all the preclinical, clinical, and manufacturing stages. Written from an FDA regulatory perspective, the book not only enables you to bring a successful ...

Oligonucleotide Based Drugs and Therapeutics

Oligonucleotide Based Drugs and Therapeutics
  • Author : Nicolay Ferrari,Rosanne Seguin
  • Publisher : John Wiley & Sons
  • Release Date : 2018-07-31
  • Total pages : 576
  • ISBN : 0123878152
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Summary : A comprehensive review of contemporary antisense oligonucleotides drugs and therapeutic principles, methods, applications, and research Oligonucleotide-based drugs, in particular antisense oligonucleotides, are part of a growing number of pharmaceutical and biotech programs progressing to treat a wide range of indications including cancer, cardiovascular, neurodegenerative, neuromuscular, and respiratory diseases, as well ...

Cancer Research

Cancer Research
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2000-11
  • Total pages : 212
  • ISBN : 0123878152
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Summary : Read online Cancer Research written by , published by which was released on 2000-11. Download full Cancer Research Books now! Available in PDF, ePub and Kindle....

Pharmacology of Ocular Therapeutics

Pharmacology of Ocular Therapeutics
  • Author : Thirumurthy Velpandian
  • Publisher : Springer
  • Release Date : 2016-02-29
  • Total pages : 535
  • ISBN : 0123878152
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Summary : This book comprises an integrated review of ocular therapeutics across all relevant fields. It addresses the real-world requirements of ophthalmologists, pharmacists and optometrists, as observed through working alongside these practitioners for two decades. Knowledge surrounding agents used in ophthalmic practice has, historically, been scattered. The book facilitates understanding of ocular ...

Pharmaceutical Salts

Pharmaceutical Salts
  • Author : P. Heinrich Stahl,Camille G. Wermuth
  • Publisher : John Wiley & Sons
  • Release Date : 2002-08-23
  • Total pages : 374
  • ISBN : 0123878152
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Summary : A team of 17 authors from academia and pharmaceutical industry, in their contributions to this book, present the necessary theoretical foundations as well as detailed practical experience in the choice of pharmaceutically active salts....

Plunkett s Biotech Genetics Industry Almanac

Plunkett s Biotech   Genetics Industry Almanac
  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2006
  • Total pages : 212
  • ISBN : 0123878152
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Summary : The only complete guide to the technologies and companies in the biotech and genetics industry....